Journal of Endocrinological Investigation

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Male sexual disturbances in liver diseases: What do we know?
Journal of Endocrinological Investigation - Tập 33 - Trang 501-505 - 2014
M. Durazzo, A. Premoli, C. Di Bisceglie, S. Bo, E. Ghigo, C. Manieri
The alterations of sexual function known as the erectile dysfunction are quite frequent among patients affected by liver diseases and they tend to increase in advanced liver failure. This process is directly linked to cirrhosis or its treatments, such as liver transplantation, or to certain drugs (e.g. beta-blockers). Independent of cirrhosis, other factors may cause sexual problems in these patie...... hiện toàn bộ
Hormonal regulation of glucose transporters in muscle cells in culture
Journal of Endocrinological Investigation - Tập 16 - Trang 147-162 - 2014
R. Sargeant, Y. Mitsumoto, V. Sarabia, G. Shillabeer, A. Klip
EP1572: A novel peptido-mimetic GH secretagogue with potent and selective GH-releasing activity in man
Journal of Endocrinological Investigation - Tập 25 - Trang RC26-RC28 - 2014
F. Broglio, F. Boutignon, A. Benso, C. Gottero, F. Prodam, E. Arvat, C. Ghè, F. Catapano, A. Torsello, V. Locatelli, G. Muccioli, D. Boeglin, V. Guerlavais, J. A. Fehrentz, J. Martinez, E. Ghigo, R. Deghenghi
EP1572 (JMV1843 [Aib-DTrp-DgTrp-CHO]) is a new peptido-mimetic GH secretagogue (GHS) showing binding potency to the GHS-receptor in animal and human tissues similar to that of ghrelin and peptidyl GHS. EP1572 induces marked GH increase after sc administration in neonatal rats. Preliminary data in 2 normal young men show that: 1) acute iv EP1572 administration (1.0 μg/kg) induces strong and selecti...... hiện toàn bộ
DNA hypermethylation of PTPN22 gene promoter in children and adolescents with Hashimoto thyroiditis
Journal of Endocrinological Investigation - Tập 44 - Trang 2131-2138 - 2020
I. Kyrgios, S. Giza, A. Fragou, G. Tzimagiorgis, A. Galli-Tsinopoulou
Protein tyrosine phosphatase non-receptor type 22 (PTPN22) is an inhibitor of T-cell activation, regulating intracellular signal transduction and thereby being implicated in the pathogenesis of autoimmune thyroid disease (AITD). The exact molecular mechanisms have not been fully elucidated. The aim of the present study was to quantitate DNA methylation within the PTPN22 gene promoter in children a...... hiện toàn bộ
Role of autoimmune and familial factors in goiter prevalence. Studies performed in a moderately endemic area
Journal of Endocrinological Investigation - Tập 9 - Trang 161-164 - 2014
Gianfranco F. Fenzi, C. Giani, P. Ceccarelli, L. Bartalena, E. Macchia, F. Aghini-Lombardi, P. Vitti, R. Lari, C. Ceccarelli, L. Baschieri, A. Pinchera
The goitrogenic role of autoimmune phenomena in endemic goiter is still uncertain. Scanty and discrepant results have been reported in different areas of the world. This prompted us to evaluate the prevalence of circulating thyroid antibodies in an area of North-Western Tuscany during a survey for endemic goiter. The survey was carried out according to the P.A.H.O. criteria in a stable community. ...... hiện toàn bộ
The treatment of hyperinsulinemic hypoglycaemia in adults: an update
Journal of Endocrinological Investigation - Tập 40 - Trang 9-20 - 2016
M. V. Davi′, A. Pia, V. Guarnotta, G. Pizza, A. Colao, A. Faggiano
Treatment of hyperinsulinemic hypoglycaemia (HH) is challenging due to the rarity of this condition and the difficulty of differential diagnosis. The aim of this article is to give an overview of the recent literature on the management of adult HH. A search for reviews, original articles, original case reports between 1995 and 2016 in PubMed using the following keywords: hyperinsulinemic hypoglyca...... hiện toàn bộ
Lack of dissociation of prolactin responses to thyrotropin releasing hormone and metoclopramide in chronic alcoholic men
Journal of Endocrinological Investigation - Tập 5 - Trang 281-286 - 2014
D. H. Van Thiel, J. S. Gavaler, A. Sanghvi
Prolactin, growth hormone and thyroid stimulating hormone responses to thyrotropin releasing hormone (TRH) and metoclopramide were determined in 12 alcoholic men with biopsy proven liver disease and were compared to those of 8 age matched normal controls. All subjects were challenged with TRH (400 μg) and metoclopramide (10 mg) given as an intravenous bolus each on a separate day. Alcoholics had i...... hiện toàn bộ
Bromocriptine acute effect on insulin, glucagon and growth hormone levels in acromegalic patients
Journal of Endocrinological Investigation - Tập 3 Số 2 - Trang 149-153 - 1980
Domenico Fedele, Maurizio Molinari, Alessandra Meneghel, Anna Valerio, Michele Muggeo, Antonio Tiengo
Rapid suppression of bone resorption and parathyroid hormone secretion by acute oral administration of calcium in healthy adult men
Journal of Endocrinological Investigation - Tập 26 - Trang 353-358 - 2014
Sergio Ortolani, A. Scotti, R. Cherubini
Acute effects of oral calcium supplementation have been studied mainly in preand post-menopausal women, whereas very few data concerning men are available. We investigated the effects of 1.2 g of oral calcium administered for 4 days in 18 healthy young men. The day before the first calcium dosing (day −1) and the day of the last calcium dosing (day 4) total and ionized serum calcium and intact PTH...... hiện toàn bộ
Cushing’s syndrome in medullary thyroid carcinoma
Journal of Endocrinological Investigation - - 1995
Agnès Mure, Christine Gicquel, N Abdelmoumene, Florence Tenenbaum, C Francese, Jean-Paul Travagli, P Gardet, Martin Schlumberger
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