Journal of Biomedical Science
Công bố khoa học tiêu biểu
* Dữ liệu chỉ mang tính chất tham khảo
Sắp xếp:
LncRNA DQ786243 affects Treg related CREB and Foxp3 expression in Crohn’s disease
Journal of Biomedical Science - Tập 20 - Trang 1-7 - 2013
Long non-coding RNAs (lncRNAs) have different functions in cells. They work as signals, decoys, guides, and scaffolds. Altered lncRNA levels can affect the expression of gene products. There are seldom studies on the role of lncRNAs in inflammatory bowel disease (IBD). Quantitative RT-PCR showed that DQ786243 was significantly overexpressed in clinical active CD patients compared with clinical ina...... hiện toàn bộ
Co-administration of dextromethorphan with methamphetamine attenuates methamphetamine-induced rewarding and behavioral sensitization
Journal of Biomedical Science - Tập 13 Số 5 - Trang 695-702 - 2006
Circulating microRNA signatures in mice exposed to lipoteichoic acid
Journal of Biomedical Science - Tập 20 - Trang 1-10 - 2013
Previously, we had identified a specific whole blood–derived microRNAs (miRNAs) signature in mice following in vivo injection of lipopolysaccharide (LPS) originated from Gram-negative bacteria. This study was designed to profile the circulating miRNAs expression in mice exposed to lipoteichoic acid (LTA) which is a major component of the wall of Gram-positive bacteria. C57BL/6 mice received intrap...... hiện toàn bộ
Acute tolerance to ethanol inhibition of NMDA-induced responses in rat rostral ventrolateral medulla neurons
Journal of Biomedical Science - Tập 11 - Trang 482-492 - 2004
The present study was performed to examine the effects of acute ethanol exposure on N-methyl-D-aspartate (NMDA)-induced responses and the development of acute tolerance in rat rostral ventrolateral medulla (RVLM) in vivo and in vitro. Repeated microinjections of NMDA (0.14 nmol) into the RVLM every 30 min caused reproducible increases in mean arterial pressure in urethane-anesthetized rats weighin...... hiện toàn bộ
An integrated method for cancer classification and rule extraction from microarray data
Journal of Biomedical Science - Tập 16 - Trang 1-10 - 2009
Different microarray techniques recently have been successfully used to investigate useful information for cancer diagnosis at the gene expression level due to their ability to measure thousands of gene expression levels in a massively parallel way. One important issue is to improve classification performance of microarray data. However, it would be ideal that influential genes and even interpreta...... hiện toàn bộ
Krüppel-like factor 10 modulates stem cell phenotypes of pancreatic adenocarcinoma by transcriptionally regulating notch receptors
Journal of Biomedical Science - Tập 30 - Trang 1-19 - 2023
Pancreatic adenocarcinoma (PDAC) is well known for its rapid distant metastasis and local destructive behavior. Loss of Krüppel-like factor 10 (KLF10) contributes to distant migration of PDAC. The role of KLF10 in modulating tumorigenesis and stem cell phenotypes of PDAC is unclear. Additional depletion of KLF10 in KC (LSL: KrasG12D; Pdx1-Cre) mice, a spontaneous murine PDAC model, was established...... hiện toàn bộ
Effects of transplanted bone marrow mesenchymal stem cells on the irradiated intestine of mice
Journal of Biomedical Science - Tập 15 - Trang 585-594 - 2008
We investigated the potency of exogenous bone marrow mesenchymal stem cells (MSCs) to engraft into irradiated intestine, as well as these cells’ effects on radiation-induced enteric injury. MSCs from β-Gal-transgenic mice were transplanted into C57BL/6J recipient mice that received abdominal irradiation (13 Gy). At different time points, recipient intestines were examined for the engraftment of do...... hiện toàn bộ
ZNF322A-mediated protein phosphorylation induces autophagosome formation through modulation of IRS1-AKT glucose uptake and HSP-elicited UPR in lung cancerAbstract
Background
ZNF322A is an oncogenic transcription factor that belongs to the Cys2His2-type zinc-finger protein family. Accumulating evidence suggests that ZNF322A may contribute to the tumorigenesis of lung cancer, however, the ZNF322A-mediated downstream signaling pathways remain unknown.... hiện toàn bộ
Journal of Biomedical Science - Tập 27 Số 1 - 2020
Tổng số: 1,777
- 1
- 2
- 3
- 4
- 5
- 6
- 10