Journal of Biological Rhythms
SCOPUS (1985-2023)SCIE-ISI
1552-4531
0748-7304
Mỹ
Cơ quản chủ quản: SAGE Publications Inc.
Lĩnh vực:
PhysiologyPhysiology (medical)
Các bài báo tiêu biểu
Life between Clocks: Daily Temporal Patterns of Human Chronotypes Human behavior shows large interindividual variation in temporal organization. Extreme “larks” wake up when extreme “owls” fall asleep. These chronotypes are attributed to differences in the circadian clock, and in animals, the genetic basis of similar phenotypic differences is well established. To better understand the genetic basis of temporal organization in humans, the authors develop... ...
Tập 18 Số 1 - Trang 80-90 - 2003
Salivary Melatonin as a Circadian Phase Marker: Validation and Comparison to Plasma Melatonin There are many situations in which it would be useful to know the phase state of the biological clock. It is recognized that measurement of melatonin levels can provide this information, but traditionally blood has been used for the analysis, and there are many problems in extending the measurements into the home or field situations. The aim of this study was to develop and validate a sal... ...
Tập 12 Số 5 - Trang 457-466 - 1997
EEG Power Density during Nap Sleep: Reflection of an Hourglass Measuring the Duration of Prior Wakefulness The relation between the duration of prior wakefulness and EEG power density during sleep in humans was assessed by means of a study of naps. The duration of prior wakefulness was varied from 2 to 20 hr by scheduling naps at 1000 hr, 1200 hr, 1400 hr, 1600 hr, 1800 hr, 2000 hr, and 0400 hr. In contrast to sleep latencies, which exhibited a minimum in the afternoon, EEG power densities in ... ...
Tập 2 Số 3 - Trang 207-219 - 1987
Getting Through to Circadian Oscillators: Why Use Constant Routines? Overt 24-h rhythmicity is composed of both exogenous and endogenous components, reflecting the product of multiple (periodic) feedback loops with a core pacemaker at their center. Researchers attempting to reveal the endogenous circadian (near 24-h) component of rhythms commonly conduct their experiments under constant environmental conditions. However, even under constant environmental c... ...
Tập 17 Số 1 - Trang 4-13 - 2002
Comparisons of the Variability of Three Markers of the Human Circadian Pacemaker A circadian pacemaker within the central nervous system regulates the approximately 24-h physiologic rhythms in sleep cycles, hormone secretion, and other physiologic functions. Because the pacemaker cannot be examined directly in humans, markers of pacemaker function must be used to study the pacemaker and its response to environmental stimuli. Core body temperature (CBT), plasma cortiso... ...
Tập 17 Số 2 - Trang 181-193 - 2002
A Model for Circadian Rhythms in Drosophila Incorporating the Formation of a Complex between the PER and TIM Proteins The authors present a model for circadian oscillations of the Period (PER) and Timeless (TIM) proteins in Drosophila. The model for the circadian clock is based on multiple phosphorylation of PER and TIM and on the negative feedback exerted by a nuclear PER-TIM complex on the transcription of the perand tim genes. Periodic behavior occurs in a large domain of parameter space in the form o... ...
Tập 13 Số 1 - Trang 70-87 - 1998
Validation of Horne and Ostberg Morningness-Eveningness Questionnaire in a Middle-Aged Population of French Workers As suggested by the authors, the Horne and Ostberg morning/evening questionnaire (MEQ) has never been adapted to evaluate a nonstudent population. The purpose of this study was to validate this MEQ in a sample of middle-aged workers by modifying only the cutoffs. It was administered in 566 non-shift-workers aged 51.2 to 3.2 years who presented no sleep disorders. According to the Horne an... ...
Tập 19 Số 1 - Trang 76-86 - 2004
Serotonin and the Mammalian Circadian System: II. Phase-Shifting Rat Behavioral Rhythms with Serotonergic Agonists The suprachiasmatic nuclei (SCN) receive primary afferents from the median and dorsal raphe, but the role of these projections in circadian timekeeping is poorly understood. Studies of the SCN in vitro suggest that quipazine, a general serotonin (5-HT) receptor agonist, can produce circadian time-dependent phase advances and phase delays in circadian rhythms of neuronal activity. The pres... ...
Tập 8 Số 1 - Trang 17-31 - 1993
Stability of Melatonin and Temperature as Circadian Phase Markers and Their Relation to Sleep Times in Humans Circadian rhythms of core body temperature and melatonin are commonly used as phase markers of the circadian clock. Melatonin is a more stable marker of circadian phase when measured under constant routine conditions. However, little is known about the variability of these phase markers under less controlled conditions. Moreover, there is little consensus about the preferred method of ana... ...
Tập 20 Số 2 - Trang 178-188 - 2005
Activity Feedback to the Mammalian Circadian Pacemaker: Influence on Observed Measures of Rhythm Period Length In the mouse, activity is precisely timed by the circadian clock and is normally most intense in the early subjective night. Since vigorous activity (e.g., wheel running) is thought to induce phase shifts in rodents, the temporal placement of daily exercise/activity could be a determinant of observed circadian rhythm period. The relationship between spontaneous running-wheel activity and ... ...
Tập 6 Số 3 - Trang 185-199 - 1991