Abstract Objectives To analyse the impact of cefiderocol use on outcome in
patients admitted to the ICU for severe COVID-19 and further diagnosed with
carbapenem-resistant Acinetobacter baumannii (CR-Ab) infection. Methods
Retrospective multicentre observational study was performed at four Italian
hospitals, from January 2020 to April 2021. Adult patients admitted to ICU for
severe COVID-19 and fu... hiện toàn bộ
Christopher Longshaw, Davide Manissero, Masakatsu Tsuji, Roger Echols, Yoshinori Yamano
AbstractObjectivesMany carbapenem-resistant (CR) Gram-negative (GN) pathogens
exhibit MDR, meaning few therapeutic options are available for CR-GN infections.
Cefiderocol, a siderophore cephalosporin, has demonstrated in vitro efficacy
against CR-GN bacteria. In the SIDERO-CR-2014–2016 surveillance study, European
clinical isolates comprising carbapenem-non-susceptible (CarbNS)
Enterobacterales an... hiện toàn bộ