Iranian journal of basic medical sciences
SCOPUS (2007-2023)SCIE-ISI
2008-3866
Cơ quản chủ quản: MASHHAD UNIV MED SCIENCES , Mashhad University of Medical Sciences
Lĩnh vực:
Clinical BiochemistryImmunology and Microbiology (miscellaneous)Drug DiscoveryBiophysicsBiochemistry
Các bài báo tiêu biểu
Effects of nano-copper on maize yield and inflammatory response in mice.
Tập 22 Số 7 - Trang 781-788 - 2019
Copper (Cu) is an essential dietary supplement in animal feeds, which plays an important role in maintaining the balance of all living organisms. Copper nanoparticles (nCu) participate in catalysing activities of multiple antioxidant/defensive enzymes and exerts pro-inflammatory and pro-apoptotic effects on systemic organs and tissues. The present study explored whether nCu affects maize growth an......
#ALT #AST #Copper #Leukocytes #Maize
Stimulation of dendritic cell functional maturation by capsid protein from chikungunya virus.
Tập 23 Số 10 - Trang 1268-1274 - 2020
Chikungunya virus (ChikV) infection is characterized by persistent infection in joints and lymphoid organs. The ChikV Capsid protein plays an important role in regulating virus replication. In this study, we hypothesized that capsid protein may stimulate dendritic cell (DC) activation and maturation and trigger an inflammatory response in mice.
#Chikungunya virus #Cytokine #Dendritic cell #MAPK #NF-κB
Changes in expression of klotho affect physiological processes, diseases, and cancer.
- 2018
Klotho (KL) encodes a single-pass transmembrane protein and is predominantly expressed in the kidney, parathyroid glands, and choroid plexus. Genetic studies on the KL gene have revealed that DNA hypermethylation is one of the major risk factors for aging, diseases, and cancer. Besides, KL exerts anti-inflammatory and anti-tumor effects by regulating signaling pathways and the expression of target......
#Aging #Calcium channel #Cancer #Dendritic cells #Klotho