Iranian journal of basic medical sciences
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Stimulation of dendritic cell functional maturation by capsid protein from chikungunya virus.
Iranian journal of basic medical sciences - Tập 23 Số 10 - Trang 1268-1274 - 2020
Chikungunya virus (ChikV) infection is characterized by persistent infection in
joints and lymphoid organs. The ChikV Capsid protein plays an important role in
regulating virus replication. In this study, we hypothesized that capsid protein
may stimulate dendritic cell (DC) activation and maturation and trigger an
inflammatory response in mice.
#Chikungunya virus #Cytokine #Dendritic cell #MAPK #NF-κB
Changes in expression of klotho affect physiological processes, diseases, and cancer.
Iranian journal of basic medical sciences - - 2018
Klotho (KL) encodes a single-pass transmembrane protein and is predominantly
expressed in the kidney, parathyroid glands, and choroid plexus. Genetic studies
on the KL gene have revealed that DNA hypermethylation is one of the major risk
factors for aging, diseases, and cancer. Besides, KL exerts anti-inflammatory
and anti-tumor effects by regulating signaling pathways and the expression of
target...
#Aging #Calcium channel #Cancer #Dendritic cells #Klotho
Effects of nano-copper on maize yield and inflammatory response in mice.
Iranian journal of basic medical sciences - Tập 22 Số 7 - Trang 781-788 - 2019
Copper (Cu) is an essential dietary supplement in animal feeds, which plays an
important role in maintaining the balance of all living organisms. Copper
nanoparticles (nCu) participate in catalysing activities of multiple
antioxidant/defensive enzymes and exerts pro-inflammatory and pro-apoptotic
effects on systemic organs and tissues. The present study explored whether nCu
affects maize growth an...
#ALT #AST #Copper #Leukocytes #Maize
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