Hypoxia Regulates the Therapeutic Potential of Mesenchymal Stem Cells Through Enhanced AutophagyInternational Journal of Lower Extremity Wounds - Tập 14 Số 1 - Trang 63-72 - 2015
Jiejie Liu, Haojie Hao, Hong Huang, Chuan Tong, Dongdong Ti, Liang Dong, Deyun Chen, Yali Zhao, Huiling Liu, Weidong Han, Xiaobing Fu
Bone marrow–derived mesenchymal stem cells (BM-MSCs)have great therapeutic
potential for the repair of diabetic lower-limb ischemia because of their
proangiogenic properties. However, cells transplanted into an ischemic
environment have reduced cell survival rates and impaired angiogenic capacity in
vivo. We explored hypoxia pretreatment as a method to promote BM-MSC survival by
inducing autophagy... hiện toàn bộ
Surgical Treatment of Limb- and Life-Threatening Infections in the Feet of Patients With Diabetes and at Least One Palpable Pedal PulseInternational Journal of Lower Extremity Wounds - Tập 10 Số 4 - Trang 207-213 - 2011
Javier Aragón‐Sánchez, José Luís Lázaro‐Martínez, Cristina Hernández-Herrero, Nalini Campillo-Vilorio, Yurena Quintana-Marrero, Esther García‐Morales, Maria J. Hernández-Herrero
Outcomes of surgically treated limb- and life-threatening infections in patients
with diabetes and a well-vascularized foot based only on the palpation of foot
pulses are not well known. The authors retrospectively studied a series of 173
patients with diabetes and limb- (moderate) or life- (severe) threatening
infections with at least one palpable pedal pulse who were admitted to their
department... hiện toàn bộ
Outcomes of Three Years of Teamwork on Critical Limb Ischemia in Patients With Diabetes and Foot LesionsInternational Journal of Lower Extremity Wounds - Tập 11 Số 2 - Trang 113-119 - 2012
Alessia Scatena, P Petruzzi, Mauro Ferrari, Loredana Rizzo, Antonio Cicorelli, Raffaella Berchiolli, Chiara Goretti, Irene Bargellini, Daniele Adami, Elisabetta Iacopi, Andrea Del Corso, Roberto Cioni, Alberto Piaggesi
To evaluate the outcomes of a multidisciplinary team working on diabetic foot
(DF) patients with critical limb ischemia (CLI) in a specialized center, the
authors retrospectively traced all the patients admitted in their department in
3 consecutive years with a diagnosis of CLI. From January 2006 to December 2008,
245 consecutive DF patients with CLI according the TransAtlantic interSociety
Consen... hiện toàn bộ
Anti-inflammatory and Wound Healing Activities of Aloe vera, Honey and Milk Ointment on Second-Degree Burns in RatsInternational Journal of Lower Extremity Wounds - Tập 15 Số 3 - Trang 241-247 - 2016
Parviz Farzadinia, Niloofar Jofreh, Saeed Khatamsaz, Ali Movahed, Samad Akbarzadeh, Mostafa Mohammadi, Afshar Bargahi
The aim of the present study was morphological and morphometric investigation of
burn healing impacts of an honey, milk, and Aloe vera (HMA) ointment on
experimentally induced second-degree burns, to approve the medicinal basis of
its use in Iranian traditional medicine. A total of 21 male Albino rats weighing
200 to 300 g were divided into 3 groups of 7, including (1) control group, (2)
positive ... hiện toàn bộ
The Evidence Supporting the Use of Honey as a Wound DressingInternational Journal of Lower Extremity Wounds - Tập 5 Số 1 - Trang 40-54 - 2006
Peter C. Molan
Some clinicians are under the impression that there is little or no evidence to
support the use of honey as a wound dressing. To allow sound decisions to be
made, this seminar article has covered the various reports that have been
published on the clinical usage of honey. Positive findings on honey in wound
care have been reported from 17 randomized controlled trials involving a total
of 1965 part... hiện toàn bộ
Turmeric (Curcuma longa) Rhizome Paste and Honey Show Similar Wound Healing Potential: A Preclinical Study in RabbitsInternational Journal of Lower Extremity Wounds - Tập 4 Số 4 - Trang 205-213 - 2005
Subarna Kundu, Tuhin Kanti Biswas, Partha Das, Saurabh Kumar, Dipak De
The potential efficacy of fresh turmeric (Curcuma longa) paste to heal wounds
was tested in a preclinical study in an animal model. Turmeric paste was
comparedwith honey as a topicalmedicament against a control on experimentally
created full-thickness circular wounds in 18 rabbits (Oryctolagous cuniculus).
Wound healing was assessed on the basis of physical, histomorphological, and
histochemical p... hiện toàn bộ
Minimally Invasive Revascularization Strategies for Chronic Lower Limb IschemiaInternational Journal of Lower Extremity Wounds - Tập 5 Số 1 - Trang 35-39 - 2006
Bart E. Muhs, Paul J. Gagne, Thomas S. Maldonado, Peter Sheehan
Lower extremity wounds resulting from ischemia are increasingly becoming a
common indication for surgical revascularization. Techniques in minimally
invasive vascular surgery for the treatment of lower extremity chronic ischemia
have expanded rapidly in recent years. The current standard of care with which
all new modalities should be compared is the restoration of arterial flow via
direct arteria... hiện toàn bộ