Turmeric (Curcuma longa) Rhizome Paste and Honey Show Similar Wound Healing Potential: A Preclinical Study in Rabbits

International Journal of Lower Extremity Wounds - Tập 4 Số 4 - Trang 205-213 - 2005
Subarna Kundu1, Tuhin Kanti Biswas2, Partha Das3, Saurabh Kumar, Dipak De4
1Department of Veterinary Surgery and Radiology, West Bengal University of Animal and Fishery Sciences, Kolkata, India. [email protected]
2Department of Sharira Kriya, J. B. Roy State Ayurvedic Medical College and Hospital
3Department of Anatomy and Histology, West Bengal University of Animal and Fishery Sciences, Kolkata, India
4Department of Veterinary Surgery and Radiology, West Bengal University of Animal and Fishery Sciences

Tóm tắt

The potential efficacy of fresh turmeric (Curcuma longa) paste to heal wounds was tested in a preclinical study in an animal model. Turmeric paste was comparedwith honey as a topicalmedicament against a control on experimentally created full-thickness circular wounds in 18 rabbits (Oryctolagous cuniculus). Wound healing was assessed on the basis of physical, histomorphological, and histochemical parameters on treatment days 0, 3, 7, and 14. Only tensile strength was measured on day 14 of treatment. It was observed that the wound healing was statistically significantly faster (P < .01) in both treatment groups compared to the control group.

Từ khóa


Tài liệu tham khảo

Myers KA, 1980, Principles of pathology in surgery, 1, 58

Probst WC, Bright MR. In: Douglas HS. Wound healing: the textbook of small animal surgery. Philadelphia: W. B. Saunders; 1985. p. 28-36.

10.1590/S0074-02762001000500026

10.1515/znc-2001-1-207

Kapur A, 1997, J Phytological Research, 10, 59

10.1248/bpb.16.235

10.1177/004947558001000219

Braniki FJ, 1981, Ann R Coll Surg Engl, 63, 348

10.1111/j.1365-2672.1992.tb04993.x

10.1080/0005772X.1992.11099109

10.1177/014107689909200604

10.1080/09674845.2003.11783668

10.1097/00000637-200301000-00027

10.1046/j.1365-2672.2003.02050.x

10.3164/jcbn.13.7

Betts JA, Proceedings of the 11th conference of the European Wound Management Association

10.1111/j.1479-828X.1992.tb02861.x

10.1097/01.SAP.0000032306.44107.C1

Tripathi KD, 1995, Essentials of medical pharmacology, 2, 785

Biswas TK, 2001, Acta Pharmacol Sin, 22, 1113

Singh UB, Sulochana S. Special stain. In: Handbook of histological and histochemical techniques. 2nd ed. Hydarabad (India): Premier; 1996-1997. p. 42-43.

Mallory FB. Pathological techniques. New York: Hafner; 1961. p. 154-155.

10.1093/ajcp/21.9_ts.897

Kumar A. Experimental evaluation of honey and an indigenous agent Canisep for their wound healing potential in goats [MVSc thesis]. Ranchi, Jharkhand, India: Birsha Agricultural University, 2002.

10.1111/j.1749-6632.2002.tb02920.x

10.1111/j.1651-2227.1998.tb01473.x

Thông tin
Thông tin xuất bản

International Journal of Lower Extremity Wounds

Tập 4 Số 4

205-213

Thông tin tác giả