Platelets: bridging hemostasis, inflammation, and immunity Tập 35 Số 3 - Trang 254-261 - 2013
Craig N. Jenne, Rossana Urrutia, Paul Kubes
SummaryAlthough the function of platelets in the maintenance of hemostasis has been studied in great detail, more recent evidence has highlighted a central role for platelets in the host inflammatory and immune responses. Platelets by virtue of their large numbers and their ability to rapidly release a broad spectrum of immunomodulatory cyto...... hiện toàn bộ Selected Stro‐1‐enriched bone marrow stromal cells display a major suppressive effect on lymphocyte proliferation Tập 31 Số 1 - Trang 9-19 - 2009
Aisha Nasef, Y. Z. ZHANG, Christelle Mazurier, Sandrine Bouchet, Morad Bensidhoum, Sabine François, N C Gorin, M López, Dominique Thierry, L Fouillard, Alain Chapel
SummaryMesenchymal stem cells (MSCs) have an immunosuppressive effect and can inhibit the proliferation of alloreactive T cells in vitro and in vivo. Cotransplantation of MSCs and hematopoietic stem cells (HSCs) from HLA‐identical siblings has been shown to reduce the incidence of acute graft‐vs... hiện toàn bộ Technical issues: flow cytometry and rare event analysis Tập 35 Số 3 - Trang 344-350 - 2013
Benjamin D. Hedley, Michael Keeney
SummaryFlow cytometry has become an essential tool for identification and characterization of hematological cancers and now, due to technological improvements, allows the identification and rapid enumeration of small tumor populations that may be present after induction therapy (minimal residual disease, hiện toàn bộ
GATA1 mutation analysis and molecular landscape characterization in acute myeloid leukemia with trisomy 21 in pediatric patients Tập 43 Số 4 - Trang 713-723 - 2021
А. В. Панферова, Marina Gaskova, Eugenyi Nikitin, Pavel Baryshev, Natalia Timofeeva, Anna Kazakova, V. E. Matveev, Ekaterina Mikhailova, А. М. Попов, И. И. Калинина, Lili Hachatrian, Aleksey Maschan, Michael Maschan, Galina Novichkova, Yulia Olshanskaya
AbstractIntroductionAccurate detection of GATA1 mutation is highly significant in patients with acute myeloid leukemia (AML) and trisomy 21 as it allows optimization of clinical protocol. This study was aimed at (a) enhanced search for GATA1 mutations; and (b) characterization ...... hiện toàn bộ Proteomics analysis reveals alterations of NK cells in patients with severe aplastic anemia Tập 42 Số 3 - Trang 308-315 - 2020
Hui Liu, Tian Zhang, Yingying Chen, Chunyan Liu, Weiwei Qi, Yuanyuan Shao, Hong Yu, Tong Chen, Shaoxue Ding, Yang Li, Ting Wang, Zonghong Shao, Rong Fu
AbstractIntroductionSevere aplastic anemia (SAA) is a disease characterized by severe pancytopenia and hematopoietic failure of bone marrow. Natural killer (NK) cells are a class of large granular lymphocytes that perform killing and immunomodulatory functions. Our previous study demonstrated that NK cells played the “protective” ...... hiện toàn bộ Routine blood biomarkers for the detection of multiple myeloma using machine learning Tập 44 Số 3 - Trang 558-566 - 2022
Gaowei Fan, Ruifang Cui, Qian Zhang, Shunli Zhang, Ruipeng Guo, Yixuan Zhai, Yuhong Yue, Qingtao Wang
AbstractIntroductionPrimary laboratory tests performed in the diagnosis of multiple myeloma (MM) include bone marrow examination and free light chain assay; however, these may only be ordered after clinical suspicion of disease. In contrast, routine blood test results are readily available.... hiện toàn bộ