International Journal of Epilepsy
SCOPUS (2014-2018,2020-2021,2023-2025)
2213-6320
Ấn Độ
Cơ quản chủ quản: Reed-Elsevier (India) Private Limited
Lĩnh vực:
Neurology (clinical)
Phân tích ảnh hưởng
Các bài báo tiêu biểu
Safety and Efficacy of Perampanel as Adjunctive Therapy in Patients with Refractory Focal Epilepsy Over 12 Months: Clinical Experience in a Real-World Setting
Tập 05 Số 02 - Trang 075-079 - 2018
Abstract Background The main purpose of this study is to assess efficacy and
tolerability of perampanel (PER), a noncompetitive
α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor antagonist, as an
add-on treatment in adult patients with refractory focal-onset seizures.
Patients and Methods A prospective, open label, observational study was
conducted in patients with refractory focal-on...
A monograph on Perampanel
Tập 3 - Trang 86-90 - 2016
AbstractPerampanel is a non-competitive antagonist at the AMPA
(alpha-amino-3-hydroxy-5-methyl-4-isoxazoleproprionic acid) subtype of
ionotropic glutamate receptor. It is approved as an adjunctive therapy in focal
epilepsy with or without secondarily generalised seizures in patients aged >12
years. This in-depth review describes the structure, mechanism of action,
pharmacokinetic profile, indicati...
Neonatal seizures and epilepsies
Tập 1 - Trang 75-83 - 2014
AbstractNeonatal seizure is the most frequent clinical manifestation of central
nervous system dysfunction in the newborn. It is defined as a paroxysmal
alteration in neurologic function that include motor, behavior and/or autonomic
functions occurring in the first 28 days after birth of a term neonate or before
44 weeks of gestational age in a preterm infant. Seizures in the presence of
encephalo...
Causative factors and phenomenology of depression in EPILEPSY—A review
Tập 4 - Trang 70-78 - 2017
AbstractIt is a known fact that depression is the one of the leading causes of
years lived with disability and the fourth leading cause of disability-adjusted
life-years worldwide. Depression is often under-recognized among patients of
epilepsy due to lack of awareness of depressive symptoms. Due to improper
management of depression in epileptic patients, it can interfere with treatment
outcomes a...
Time to treatment predicts seizure outcome in a high-treatment gap epilepsy population
Tập 2 - Trang 72-77 - 2015
Abstract Objectives To investigate the relationship between time to
antiepileptic drug (AED) treatment (TTT) and seizure outcome in a high treatment
gap sub-Sahara African setting. Methods Clinical and demographic characteristics
of 72 adults with epilepsy aged 18–75 years were obtained. We estimated TTT as
the difference between the duration of epilepsy and the duration of treatment.
Indices of c...
Plasma tetranectin as a potential clinical biomarker for epilepsy and correlation with clinical and social characteristics
Tập 4 - Trang 2-5 - 2017
Abstract Background Tetranectin concentration has been identified as a biomarker
of several types of metastatic and malignant cancers. The role of tetranectin
has also be seen in some neurological disorders. We aimed to estimate the plasma
tetranectin concentration in different groups of people with epilepsy (PWE)
followed-up for a year. As a secondary objective, the clinical and social
characteri...
Hồ sơ tương tác khác biệt của gabapentin và levetiracetam với lipid dipalmitoylphosphatidylcholine Dịch bởi AI
Tập 4 - Trang 150 - 2017
Bối cảnh/Mục tiêu Độ tan trong lipid của các thuốc chống co giật ảnh hưởng trực
tiếp đến khả dụng trong hệ thần kinh trung ương. Liên quan đến điều này, các
tương tác của gabapentin và levetiracetam với lipid
dipalmitoylphosphatidylcholine phụ thuộc vào nồng độ đã được nghiên cứu một cách
so sánh trong nghiên cứu hiện tại. Phương pháp Các tác động của gabapentin và
levetiracetam theo nồng độ (1–5–...
#Gabapentin #Levetiracetam #Dipalmitoylphosphatidylcholines #Fourier transform infrared spectroscopy #Differential scanning calorimetry
Clinical, MRI and electrographic characteristics of three children with Hemiconvulsion-Hemiplegia/Hemiconvulsion-Hemiplegia-Epilepsy (HH/HHE) syndrome–A rare childhood epileptic encephalopathy
Tập 4 - Trang 79-86 - 2017
AbstractHemi convulsion-Hemiplegia-Epilepsy (HH/HHE) syndrome is a very rare
catastrophic epileptic syndrome in childhood which follows a prolonged focal
motor status epilepticus in infancy and early childhood. Here we are describing
the clinical, MRI and electrographic characteristics along with long term
outcome of three children with HH/HHE syndrome. A review of the current
literature on HH/HHE...
A first-ever dedicated comprehensive review of incidence of epilepsy in South America and Caribbean
Tập 4 - Trang 65-69 - 2017
AbstractIn order to understand true incident burden of epilepsy in South America
and Caribbean, several sources were searched in multiple languages using
keywords and combinations. The results were presented as counts, proportions,
means, and/or medians along with their 95% confidence intervals (CI). No
information was found from Caribbean and no information was available from six
South American c...
Cognitive deficits in the first 24 hours after the onset of first unprovoked generalized Tonic and clonic seizure
Tập 4 - Trang 141-143 - 2017
AbstractBackground Many people with epilepsy suffer from cognitive deficits as a
consequence of their seizure episodes. Relatively few researches have been
undertaken to assess the short term impacts of seizure on cognitive function.
This study aimed to evaluate changes in cognitive performance in adults with a
new onset generalized seizure in the first 24 h after the onset of their
attack.Methods...