International Journal of Epilepsy
SCOPUS (2014-2018,2020-2021,2023-2025)
2213-6320
Ấn Độ
Cơ quản chủ quản: Reed-Elsevier (India) Private Limited
Lĩnh vực:
Neurology (clinical)
Phân tích ảnh hưởng
Các bài báo tiêu biểu
Safety and Efficacy of Perampanel as Adjunctive Therapy in Patients with Refractory Focal Epilepsy Over 12 Months: Clinical Experience in a Real-World Setting
Tập 05 Số 02 - Trang 075-079 - 2018
Abstract Background The main purpose of this study is to assess efficacy and
tolerability of perampanel (PER), a noncompetitive
α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor antagonist, as an
add-on treatment in adult patients with refractory focal-onset seizures.
Patients and Methods A prospective, open label, observational study was
conducted in patients with refractory focal-on...
Bone health in epilepsy
Tập 4 - Trang 59-64 - 2017
AbstractEpilepsy is one of the most common neurological disorder usually
requiring life long treatment. Long term treatment with antiepileptic drugs
(AED’s) is associated with chronic side effects which includes effect on bone
healthThere is a growing volume of literature suggesting that chronic use of AED
in patients with epilepsy significantly reduces bone mineral density (BMD) with
an increased...
Cognitive deficits in the first 24 hours after the onset of first unprovoked generalized Tonic and clonic seizure
Tập 4 - Trang 141-143 - 2017
AbstractBackground Many people with epilepsy suffer from cognitive deficits as a
consequence of their seizure episodes. Relatively few researches have been
undertaken to assess the short term impacts of seizure on cognitive function.
This study aimed to evaluate changes in cognitive performance in adults with a
new onset generalized seizure in the first 24 h after the onset of their
attack.Methods...
A case of paroxysmal nocturnal dystonia responsive to cyproheptadine: Is it almost always epileptic?
Tập 2 - Trang 49-50 - 2015
AbstractNocturnal Paroxysmal Dystonia (NPD) is characterized by abnormal
dyskinetic movements occur mostly during non-REM sleep. From introducing NPD in
early 1980s, most authors have been in favour of an epileptic origin for these
sleep-related episodes. Clinical characteristics of NPD including abrupt
hypermotor behaviours, automatisms and vocalizations, abnormal EEG findings in
some patients an...
Ring chromosome 20 syndrome – A rare chromosomal cause of refractory epilepsy in children
Tập 4 - Trang 87-89 - 2017
AbstractGenetic disorders and chromosomal abnormalities have been shown to
represent 2–3% of all cases of epilepsy. Ring chromosome 20 syndrome is a rare
chromosomal abnormality and a rare cause of intractable epilepsy. Exact
prevalence of ring chromosome 20 is not known. We report a case of a 10-year old
boy who had had intractable epilepsy since 2 years of age. Birth history was
insignificant an...
Evaluation of DNA damage and mutation screening of exon 26 of SCN1A gene in patients with epilepsy
Tập 4 - Trang 125-131 - 2017
Abstract Background Epilepsy is one of the most prevalent neurological
disorders. Around 50 million people worldwide suffer from Epilepsy, 85% of them
are from the developing countries. It is a most significant as well as common
brain disorder worldwide. Sodium channel alpha 1 subunit gene (SCN1A) is most
commonly mutated the gene in different forms of epilepsy. Objective To screen
the genomic dam...
Plasma tetranectin as a potential clinical biomarker for epilepsy and correlation with clinical and social characteristics
Tập 4 - Trang 2-5 - 2017
Abstract Background Tetranectin concentration has been identified as a biomarker
of several types of metastatic and malignant cancers. The role of tetranectin
has also be seen in some neurological disorders. We aimed to estimate the plasma
tetranectin concentration in different groups of people with epilepsy (PWE)
followed-up for a year. As a secondary objective, the clinical and social
characteri...
Diffusion tensor imaging correlates of hippocampal sclerosis and anterior temporal lobe T2 signal changes in pharmacoresistant epilepsy
Tập 1 - Trang 1-7 - 2014
AbstractBackground and purpose Our goal was to determine fiber tract integrity
in hippocampal sclerosis (HS) using diffusion tensor imaging (DTI) and to
correlate white matter damage with other pathology in this disease.Methods
Twenty-six patients and eight controls were studied with DTI tractography for 8
pairs of white matter fiber tracts and 2 commissural tracts. Fractional
anisotropy (FA) of t...
Neonatal seizures and epilepsies
Tập 1 - Trang 75-83 - 2014
AbstractNeonatal seizure is the most frequent clinical manifestation of central
nervous system dysfunction in the newborn. It is defined as a paroxysmal
alteration in neurologic function that include motor, behavior and/or autonomic
functions occurring in the first 28 days after birth of a term neonate or before
44 weeks of gestational age in a preterm infant. Seizures in the presence of
encephalo...
A monograph on Perampanel
Tập 3 - Trang 86-90 - 2016
AbstractPerampanel is a non-competitive antagonist at the AMPA
(alpha-amino-3-hydroxy-5-methyl-4-isoxazoleproprionic acid) subtype of
ionotropic glutamate receptor. It is approved as an adjunctive therapy in focal
epilepsy with or without secondarily generalised seizures in patients aged >12
years. This in-depth review describes the structure, mechanism of action,
pharmacokinetic profile, indicati...