International Journal of Epilepsy
SCOPUS (2014-2018,2020-2021,2023-2025)
2213-6320
Ấn Độ
Cơ quản chủ quản: Reed-Elsevier (India) Private Limited
Lĩnh vực:
Neurology (clinical)
Phân tích ảnh hưởng
Các bài báo tiêu biểu
Safety and Efficacy of Perampanel as Adjunctive Therapy in Patients with Refractory Focal Epilepsy Over 12 Months: Clinical Experience in a Real-World Setting
Tập 05 Số 02 - Trang 075-079 - 2018
Abstract Background The main purpose of this study is to assess efficacy and
tolerability of perampanel (PER), a noncompetitive
α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor antagonist, as an
add-on treatment in adult patients with refractory focal-onset seizures.
Patients and Methods A prospective, open label, observational study was
conducted in patients with refractory focal-on...
Proprioceptive-induced seizure in diabetic non-ketotic state: A video case report
Tập 1 - Trang 36-38 - 2014
AbstractA 63-year-old diabetic gentleman with proprioceptive-induced seizures is
reported. Marked hyperglycemia due to discontinuation of anti-diabetic
medication was the precipitating cause. Distinctive clinical feature of this
case was recurrent focal motor seizures involving the left upper limb
precipitated by volitional movements of the same limb and self-aborted by
holding the affected limb w...
To evaluate the anti-kindling effect of allopregnanolone alone and its interaction with sodium valporate in pentylenetetrazole induced kindling model
Tập 3 - Trang 68-74 - 2016
Abstract Background and purpose Studies in the animal models of epilepsy have
suggested the anti-seizure effects of neuroactive steroids and its derivatives
in kainic acid and pilocarpine induced limbic seizures and status epilepticus in
mice, but no such studies have been reported in the published literature on the
role of allopregnanolone in chemical kindling model and its interaction with
sodiu...
A first-ever dedicated comprehensive review of incidence of epilepsy in South America and Caribbean
Tập 4 - Trang 65-69 - 2017
AbstractIn order to understand true incident burden of epilepsy in South America
and Caribbean, several sources were searched in multiple languages using
keywords and combinations. The results were presented as counts, proportions,
means, and/or medians along with their 95% confidence intervals (CI). No
information was found from Caribbean and no information was available from six
South American c...
Cognitive outcome in epileptic patients in a tertiary care centre in Kolkata, India
Tập 3 - Trang 64-67 - 2016
Abstract Objective The objective of the study is to assess the diverse cognitive
dysfunctions in epileptic patients. Methods Generalized tonic–clonic seizure
(GTCS) and complex partial seizure (CPS) patients and those control matched and
assessed for their IQ were undertaken for the present study. ANOVA test was used
to assess the differences between GTCS and CPS with the control. Results GTCS
and...
Bổ sung taurine vào thuốc chống co giật như một phương pháp hứa hẹn để điều trị động kinh kháng thuốc: Một nghiên cứu tiền lâm sàng Dịch bởi AI
Tập 4 - Trang 119-124 - 2017
Giới thiệuĐặc điểm kháng thuốc dẫn đến những khuyết tật nghiêm trọng, không thể
phục hồi và tử vong sớm trong khoảng 30% trường hợp động kinh mặc dù đã được
điều trị đầy đủ và hợp lý bằng các loại thuốc chống co giật (ASDs) có sẵn mà
không có nguyên nhân tiềm ẩn. Dựa trên một khối lượng lớn chứng cứ cho thấy tác
dụng chống co giật của taurine ở động vật thí nghiệm và biên độ an toàn rộng rãi
ở ngư...
Plasma tetranectin as a potential clinical biomarker for epilepsy and correlation with clinical and social characteristics
Tập 4 - Trang 2-5 - 2017
Abstract Background Tetranectin concentration has been identified as a biomarker
of several types of metastatic and malignant cancers. The role of tetranectin
has also be seen in some neurological disorders. We aimed to estimate the plasma
tetranectin concentration in different groups of people with epilepsy (PWE)
followed-up for a year. As a secondary objective, the clinical and social
characteri...
A child with global neuroregression with refractory epilepsy
Tập 1 - Trang 92-93 - 2014
AbstractHypomyelinating disorders have wide spectrum of clinical and
radiological manifestations. A 17-month-old girl presented with baseline global
developmental delay with insidious onset global neuroregression with refractory
seizures from 1 year of age. Her birth and family history were noncontributory.
Salient features on examination were central hypotonia and retinal cherry red
spot. MRI Bra...
Cognitive deficits in the first 24 hours after the onset of first unprovoked generalized Tonic and clonic seizure
Tập 4 - Trang 141-143 - 2017
AbstractBackground Many people with epilepsy suffer from cognitive deficits as a
consequence of their seizure episodes. Relatively few researches have been
undertaken to assess the short term impacts of seizure on cognitive function.
This study aimed to evaluate changes in cognitive performance in adults with a
new onset generalized seizure in the first 24 h after the onset of their
attack.Methods...
A monograph on Perampanel
Tập 3 - Trang 86-90 - 2016
AbstractPerampanel is a non-competitive antagonist at the AMPA
(alpha-amino-3-hydroxy-5-methyl-4-isoxazoleproprionic acid) subtype of
ionotropic glutamate receptor. It is approved as an adjunctive therapy in focal
epilepsy with or without secondarily generalised seizures in patients aged >12
years. This in-depth review describes the structure, mechanism of action,
pharmacokinetic profile, indicati...