The International Journal of Epidemiology is an essential requirement for anyone who needs to keep up to date with epidemiological advances and new developments throughout the world. It encourages communication among those engaged in the research, teaching, and application of epidemiology of both communicable and non-communicable disease, including research into health services and medical care. Also covered are new methods, epidemiological and statistical, for the analysis of data used by those who practise social and preventive medicine. The International Journal of Epidemiology is published six times yearly.
Esther Aspinall, Dhanya Nambiar, David Goldberg, Matthew Hickman, Alan Weir, Eva van Velzen, Norah Palmateer, Joseph Doyle, Margaret Hellard, Sharon Hutchinson
Hans‐Peter Kohler, Susan Cotts Watkins, Jere R. Behrman, Philip Anglewicz, Iliana V. Kohler, Rebecca Thornton, James Mkandawire, Hastings Honde, Augustine Hawara, Ben Chilima, Chiwoza Bandawe, Victor Mwapasa, Peter Fleming, Linda Kalilani‐Phiri
Mette Reilev, Kasper Bruun Kristensen, Anton Pottegård, Lars Christian Lund, Jesper Hallas, Martin Ernst, Christian Fynbo Christiansen, Henrik Toft Sørensen, Nanna B. Johansen, Nikolai C. Brun, Marianne Voldstedlund, Henrik Støvring, Marianne Kragh Thomsen, Steffen Christensen, Sophie Gubbels, Tyra Grove Krause, Kåre Mølbak, Reimar W. Thomsen
AbstractBackgroundPopulation-level knowledge on individuals at high risk of severe and fatal coronavirus disease 2019 (COVID-19) is urgently needed to inform targeted protection strategies in the general population.MethodsWe examined characteristics and predictors of hospitalization and death in a nationwide cohort of all Danish individuals tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from 27 February 2020 until 19 May 2020.ResultsWe identified 11 122 SARS-CoV-2 polymerase chain reaction-positive cases of whom 80% were community-managed and 20% were hospitalized. Thirty-day all-cause mortality was 5.2%. Age was strongly associated with fatal disease {odds ratio [OR] 15 [95% confidence interval (CI): 9–26] for 70–79 years, increasing to OR 90 (95% CI: 50–162) for ≥90 years, when compared with cases aged 50–59 years and adjusted for sex and number of co-morbidities}. Similarly, the number of co-morbidities was associated with fatal disease [OR 5.2 (95% CI: 3.4–8.0), for cases with at least four co-morbidities vs no co-morbidities] and 79% of fatal cases had at least two co-morbidities. Most major chronic diseases were associated with hospitalization, with ORs ranging from 1.3–1.4 (e.g. stroke, ischaemic heart disease) to 2.6–3.4 (e.g. heart failure, hospital-diagnosed kidney disease, organ transplantation) and with mortality with ORs ranging from 1.1–1.3 (e.g. ischaemic heart disease, hypertension) to 2.5–3.2 (e.g. major psychiatric disorder, organ transplantation). In the absence of co-morbidities, mortality was <5% in persons aged ≤80 years.ConclusionsIn this nationwide population-based COVID-19 study, increasing age and multimorbidity were strongly associated with hospitalization and death. In the absence of co-morbidities, the mortality was, however, <5% until the age of 80 years.
Chỉ số ảnh hưởng
Total publication
2
Total citation
171
Avg. Citation
85.5
Impact Factor
0
H-index
2
H-index (5 years)
2
i10
1
i10-index (5 years)
0
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