International Journal of Clinical and Laboratory Research

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Determination of serum levels of complement component C4b-binding protein: influence of age and inflammation
International Journal of Clinical and Laboratory Research - Tập 21 - Trang 171-175 - 1992
Santica M. Marcovina, Adele Zoppo, Silvana Viganó-D'Angelo, Giovanni Di Cola, Armando D'Angelo
C4b-binding protein (C4b-BP) is a high molecular weight plasma protein which inhibits the activity of the classical complement pathway C3 convertase. In addition to multiple binding sites for C4b, C4b-BP possesses a single binding site for vitamin K-dependent protein S, an inhibitor of blood coagulation. As protein S bound to C4b-BP has no anticoagulant activity, C4b-BP participates in the regulat...... hiện toàn bộ
The problem of infections in acute leukemias
International Journal of Clinical and Laboratory Research - Tập 6 - Trang 319-325 - 1976
Piero Serra, Camillo Brandimarte, Piero Martino, Franco Mandelli
This report is based on experience over the last 5 years in the diagnosis and treatment of infections in 200 acute leukemic patients hospitalized in the Institute of Haematology, University of Rome. The relevant clinical and laboratory findings are discussed in relation to the diagnosis of secondary infections. Most of the febrile episodes were associated with infection. The frequently rapid devel...... hiện toàn bộ
Measures of tumor proliferative activity
International Journal of Clinical and Laboratory Research - Tập 22 - Trang 196-200 - 1992
D. J. Brooks, H. S. Garewal
Tumor proliferative activity, or labeling index, is of interest for gaining insight into the biologic properties of human neoplasm and for providing clinical information that might guide patient management. There has been an abundance of literature reporting experience with standard and newer techniques of measuring tumor proliferative activity. These methods are reviewed with emphasis on technica...... hiện toàn bộ
Role of plasma-exchange in the management of patients with factor VIII inhibitors
International Journal of Clinical and Laboratory Research - Tập 13 - Trang 85-93 - 1983
Brian T. Colvin
Plasma-exchange is one of many treatments available for the prevention and management of hemorrhage in patients with factor VIII inhibitors. Details of exchange technique and the frequency of treatment are determined by the clinical situation, venous access and the availability of equipment, staff and blood products. In view of the many difficulties associated with plasma-exchange, other treatment...... hiện toàn bộ
HIV-1-infected monocytes and monocyte-derived macrophages are impaired in their ability to produce Superoxide radicals
International Journal of Clinical and Laboratory Research - Tập 27 - Trang 111-117 - 1997
A. L. Howell, D. S. Groveman, P. K. Wallace, M. W. Fanger
Monocytes and monocyte-derived macrophages play a key role in immune defense against pathogenic organisms. Superoxide anion production is a key mechanism by which phagocytes kill pathogens. We sought to determine whether human immunodeficiency virus-infected monocytes and monocyte-derived macrophages are compromised in their ability to produce the Superoxide anion following stimulation with phorbo...... hiện toàn bộ
Immunological studies of an antiviral monoclonal IgG cryoglobulin
International Journal of Clinical and Laboratory Research - Tập 10 - Trang 41-47 - 1980
Jean-Charles Renversez, Jean-Marie Seigneurin, Claire Marie Barioz
Antigen perception by T lymphocytes
International Journal of Clinical and Laboratory Research - Tập 6 Số 4 - Trang 285-299 - 1976
Miller, Jacques F. A. P.
There is considerable evidence that T cell activation to soluble antigens occurs only if this is processed by macrophages and displayed appropriately on the plasma membrane in association with products of the genes of the major histocompatibility complex. The genes responsible differ according to the antigens involved. For cytotoxicity, targets and killer T cells must share K or D region gene prod...... hiện toàn bộ
The undefined relationship between tumor antigens and histocompatibility antigens on cancer cells
International Journal of Clinical and Laboratory Research - Tập 10 - Trang 481-492 - 1980
Giorgio Parmiani, Giuseppe Fossati, Giuseppe Della Porta
The data pertaining to the possible relationship between histocompatibility antigens (HA) and tumor-specific transplantation or tumor surface antigen (TSTA or TSA) are reviewed. The HA profiles of certain experimental and human neoplasms have been found to be altered either from the quantitative (increased expression of some antigenic specificities and decreased expression or even lack of other HA...... hiện toàn bộ
Studies of protein C in thromboembolic disease
International Journal of Clinical and Laboratory Research - Tập 14 - Trang 469-473 - 1984
John H. Griffin, Annie Bezeaud, Bruce Evatt, Deane Mosher
Tổng số: 822   
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