Grass pollens are one of the most important airborne allergen sources worldwide. About 20 species from five subfamilies are considered to be the most frequent causes of grass pollen allergy, and the allergenic relationships among them closely follow their phylogenetic relationships. The allergic immune response to pollen of several grass species has been studied extensively over more than ...... hiện toàn bộ
Antibodies to polyethylene glycol (PEG) were raised in rabbits by immunization with monomethoxy polyethylene glycol modified ovalbumin (OA), bovine superoxide dismutase (SOD), and ragweed pollen extract (Rag), given in Freund’s complete adjuvant (FCA). Immunogenicity depended on the nature of the protein and the degree of modification. With modified OA, in the presence of FCA, the majority...... hiện toàn bộ
<b>Background:</b><i>Lactobacillus casei</i> is a nonpathogenic gram-positive bacterium widely used in dairy products and has been shown to enhance the cellular immunity of the host. <b>Methods:</b> To examine the inhibitory effect of <i>L. casei</i> on IgE production, splenocytes obtained from ovalbumin (OVA)-primed BALB/c mice were restimul...... hiện toàn bộ
G. Sandra Tjabringa, Dennis K. Ninaber, Jan W. Drijfhout, Klaus F. Rabe, Pieter S. Hiemstra
<i>Background:</i> Inflammatory lung diseases such as asthma and chronic obstructive pulmonary disease (COPD) are characterized by the presence of eosinophils and neutrophils. However, the mechanisms that mediate the influx of these cells are incompletely understood. Neutrophil products, including neutrophil elastase and antimicrobial peptides such as neutrophil defensins and L...... hiện toàn bộ
Didier Cataldo, Carine Munaut, Agnès Noël, Françis Frankenne, Pierre Bartsch, J.M. Foidart, Renaud Louis
<i>Background:</i> The course of asthma and chronic obstructive pulmonary disease (COPD) is associated with bronchial morphological changes. Metalloproteinases are thought to play a role in these structural changes. <i>Methods:</i> We studied the gelatinolytic activity present in the induced sputum from 20 patients with asthma, 20 with COPD and 19 healthy controls. ...... hiện toàn bộ
Eunkyung Park, Min‐Kyung Choo, Myung Joo Han, Dong‐Hyun Kim
<i>Background:</i> Ginseng (the root of <i>Panax ginseng</i> C.A. Meyer, Araliaceae) has been reported to possess various biological activities, including anti-inflammatory and antitumor actions. In this study, we investigated the antiallergic activity of ginsenosides isolated from ginseng. <i>Method:</i> We isolated ginsenosides by silica gel column chr...... hiện toàn bộ
<i>Background:</i> IgE to cross-reacting carbohydrate determinants has already been described by several authors, but their function and distribution are still a matter of debate. In previous studies we showed how the presence of IgE to bromelain could be a useful and simple marker of the presence of IgE to carbohydrate epitopes. <i>Methods:</i> A survey of 1,831 su...... hiện toàn bộ