Infectious Diseases of Poverty
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Development of antimalarial drugs and their application in China: a historical review
Infectious Diseases of Poverty - Tập 3 - Trang 1-10 - 2014
This historical review covers antimalarials developed in China, which include artemisinin, artemether, artesunate, and dihydroartemisinin, as well as other synthetic drugs such as piperaquine, pyronaridine, benflumetol (lumefantrine), and naphthoquine. The curative effects of these antimalarials in the treatment of falciparum malaria, including chloroquine-resistant strain, are especially discusse......
A qualitative exploration of Pakistan’s street children, as a consequence of the poverty-disease cycle
Infectious Diseases of Poverty - Tập 3 - Trang 1-8 - 2014
Street children are a global phenomenon, with an estimated population of around 150 million across the world. These children include those who work on the streets but retain their family contacts, and also those who practically live on the streets and have no or limited family contacts. In Pakistan, many children are forced to work on the streets due to health-related events occurring at home whic......
Control programs for strongyloidiasis in areas of high endemicity: an economic analysis of different approaches
Infectious Diseases of Poverty - Tập 10 - Trang 1-10 - 2021
Implementation of control programmes for Strongyloides stercoralis infection is among the targets of the World Health Organization Roadmap to 2030. Aim of this work was to evaluate the possible impact in terms of economic resources and health status of two different strategies of preventive chemotherapy (PC) compared to the current situation (strategy A, no PC): administration of ivermectin to sch......
Chromosome-scale genome of the human blood fluke Schistosoma mekongi and its implications for public health
Infectious Diseases of Poverty - Tập 12 - Trang 1-17 - 2023
Schistosoma mekongi is a human blood fluke causing schistosomiasis that threatens approximately 1.5 million humans in the world. Nonetheless, the limited available S. mekongi genomic resources have hindered understanding of its biology and parasite-host interactions for disease management and pathogen control. The aim of our study was to integrate multiple technologies to construct a high-quality ......
Disability progression among leprosy patients released from treatment: a survival analysis
Infectious Diseases of Poverty - Tập 9 - Trang 1-7 - 2020
Leprosy can be cured, but physical disability (PD) as a result of the infection can progress in the post-release from treatment phase. This study evaluated the likelihood of, and factors associated with, the progression of the PD grade post-release from treatment among leprosy patients treated in Cáceres-MT, Brazil in the period 2000 to 2017. A retrospective cohort study and survival analysis were......
Epidemiological characterization of imported recurrent Plasmodium vivax and Plasmodium ovale in China, 2013–2020
Infectious Diseases of Poverty - Tập 10 - Trang 1-10 - 2021
China has reached important milestones in the elimination of malaria. However, the numbers of imported recurrent cases of Plasmodium vivax and P. ovale are gradually increasing, which increases the risk of malaria re-establishment in locations where Anopheles mosquitoes exist. The aim of this study is to characterize the epidemiological profiles of imported recurrent P. vivax and P. ovale cases, q......
Developing a comprehensive response for treatment of children under 6 years of age with schistosomiasis: research and development of a pediatric formulation of praziquantel
Infectious Diseases of Poverty - Tập 6 - Trang 1-4 - 2017
Schistosomiasis is a parasitic disease caused by blood flukes. The disease is caused by an inflammatory reaction to parasite eggs retained in the liver, bladder and reproductive organs. According to 2017 World Health Organization (WHO) estimates 220 million people are potentially infected, from which probably 10% are children under 6 years of age. The regular treatment approach of a single, oral d......
Malaria epidemiology and interventions in Ethiopia from 2001 to 2016
Infectious Diseases of Poverty - Tập 7 - Trang 1-9 - 2018
Ethiopia is one of the African countries where Plasmodium falciparum and P. vivax co-exist. Monitoring and evaluation of current malaria transmission status is an important component of malaria control as it is a measure of the success of ongoing interventions and guides the planning of future control and elimination efforts. We evaluated changes in malaria control policy in Ethiopia, and reviewed......
A case of brucellosis concomitant with HIV infection in China
Infectious Diseases of Poverty - Tập 9 - Trang 1-5 - 2020
Human brucellosis is a neglected public health issue in China and reports of HIV-infected individuals complicated with brucellosis are rare. This report describes the case of an HIV-infected patient complicated with brucellosis. We want to raise awareness of clinical diagnosis of brucellosis among clinicians. Furthermore, we should be more concerned about cases with pyrexia of unknown origin, espe......
Burden of onchocerciasis-associated epilepsy: first estimates and research priorities
Infectious Diseases of Poverty - Tập 7 - Trang 1-12 - 2018
Since the 1990s, evidence has accumulated of an increased prevalence of epilepsy in onchocerciasis-endemic areas in Africa as compared to onchocerciasis-free areas. Although the causal relationship between onchocerciasis and epilepsy has yet to be proven, there is likely an association. Here we discuss the need for disease burden estimates of onchocerciasis-associated epilepsy (OAE), provide them,......
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