Indian Journal of Gynecologic Oncology
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An Unusual Missed Case of Endometrial Stromal Sarcoma
Indian Journal of Gynecologic Oncology - Tập 13 - Trang 1-3 - 2015
Endometrial stromal sarcomas are rare uterine malignant tumours of mesodermal origin. The diagnosis is usually made post-operatively. The usual presentation is abnormal vaginal bleeding, abdominal lump and mild lower abdominal pain. In this case report, we present a case of low-grade endometrial stromal sarcoma where patient was initially thought to have fibroid uterus with cystic degenerative cha......
Risk Factor Associations of Breast Cancer Among Women Attending Out-Patients Department of the Hospital: A Case vs. Control Study
Indian Journal of Gynecologic Oncology - - 2021
Evaluation of Serum s EGFR in Ovarian Tumors, its Comparison with Serum CA125, HE4 and Correlation with Histopathological Types
Indian Journal of Gynecologic Oncology - Tập 19 - Trang 1-6 - 2021
EGFR is deregulated, in several types of cancer, by three mechanisms: (1) activating gene mutations; (2) overexpression of the EGFR transmembrane form and (3) altered ligand expression. Selective EGFR inhibitors have been suggested as first-line therapy in lung cancer patients harboring EGFR mutations, tumors of the pancreas and certain histotypes of ovarian tumors. Carbohydrate antigen 125(CA125)......
siRNA and Ovarian Cancer
Indian Journal of Gynecologic Oncology - Tập 19 - Trang 1-13 - 2021
RNA interference (RNAi) is an emerging field of genetic intervention of the new millennium for incurable disease conditions where conventional treatment fails. MicroRNA (miRNA) and small interfering RNA (siRNA) are two components of such RNAi. Exogenous double-stranded siRNA targets specific mRNA and prevents anomalous gene expression producing such disease conditions. Ovarian cancer is such a dis......
Epidemiological and Survival Trends in Patients of Cancer of Uterine Cervix Treated with Definitive Concurrent Chemoradiotherapy: Observations from a North Indian Hospital-Based Cancer Registry
Indian Journal of Gynecologic Oncology - - 2019
Worldwide, cervical cancer is the fourth most common cancer in women and a significant proportion of this cancer comes from India. Identifying various prognostic factors on survival outcomes will help us in giving better care and thereby prolonging life of these patients. Objective of this study was to assess various factors and their association with outcomes in terms of overall survival (OS) and......
Identification of Key Candidate Genes in the Progression of Cervical Cancer: An in Silico Analysis
Indian Journal of Gynecologic Oncology - Tập 20 - Trang 1-8 - 2022
Cervical cancer is one of the most widespread gynaecological tumours in women, and the molecular pathogenesis and chances of recurrence of the illness are still not clear. It is critical to identify new biomarkers to detect cervical cancer sooner to minimize women’s incidence and mortality rates.
Differentially expressed genes were screened from the GSE64517 transcriptome profile. A protein–prote......
Use of Bevacizumab in Advanced Ovarian Cancer: Consensus from an Expert Panel Oncologists
Indian Journal of Gynecologic Oncology - Tập 19 - Trang 1-8 - 2021
To discuss and reach a consensus on the use of bevacizumab in women with advanced ovarian cancer in Indian settings.
An advisory board meeting comprising Indian oncologists was convened to review key literature available on the role of bevacizumab in the management of advanced ovarian cancer. Key recommendations were devised via consensus by the expert panel based on the analysis of available sci......
Diagnostic and Prognostic Significance of AgNOR Counts in Before and After Radiotherapy-Treated Cervical Carcinogenesis is Compared with Cervical Cytology and Histology
Indian Journal of Gynecologic Oncology - Tập 18 - Trang 1-7 - 2020
Nucleolar organizer region-associated proteins are argyrophilic and visualized by silver stains. There are two types of dots are present. One is the presence of single dots, and another is pleomorphic dots. Pleomorphic dots are few, increase with severity of cervical lesions and hence indicate a more severe prognosis. The present study aimed at investigating the diagnostic value of both pleomorphi......
Is Routine Nodal Dissection in Early Epithelial Ovarian Cancers Required?
Indian Journal of Gynecologic Oncology - Tập 18 - Trang 1-5 - 2020
The staging of ovarian cancer is unique because it is done surgically, wherein, along with hysterectomy and bilateral oophorectomy, pelvic and para-aortic nodes are routinely removed to find evidence of metastatic disease, which is not detected clinically. With advances in imaging modalities, it is now possible to predict, with reasonable accuracy, whether a regional lymph node is metastatic or no......
ICG-Based Sentinel Lymph Node Biopsy in Endometrioid Endometrial Carcinoma—Results of a Prospective Study from a Single Tertiary Cancer Center of India
Indian Journal of Gynecologic Oncology - Tập 19 - Trang 1-11 - 2021
Lymphadenectomy is the most accurate method of assessment of lymph node involvement in carcinoma endometrium. The benefit of lymphadenectomy in endometrial cancer is still unproven. Sentinel lymph node (SLN) evaluation is of growing importance because of less morbidity and good diagnostic accuracy. Identification rates, sensitivity, specificity, negative predictive value and positive predictive va......
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