Immunology and Cell Biology

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T‐cell migration: Kruppeled T cells move again
Immunology and Cell Biology - Tập 86 Số 4 - Trang 297-298 - 2008
Kristin A. Hogquist, Michael Weinreich, Stephen C. Jameson
Differences in antigen‐binding affinity caused by single amino acid substitution in the variable region of the heavy chain
Immunology and Cell Biology - Tập 71 Số 4 - Trang 239-247 - 1993
Jim Xiang, Zhi‐Nan Chen, Louis T. J. Delbaere, Enwu Liu
SummarySite‐directed mutagenesis has been used to examine the importance of histidine‐99 in the VH CDR3 region of a mouse/human chimeric anti‐TAG72 antibody, cB72.3‐1‐3. The expression vectors mpSV2neo‐EPl‐Vm4–10C.γ1, containing seven different mutant VH region fragments (V... hiện toàn bộ
Influence of antigens and adjuvants on the production of gamma‐interferon and antibody by ovine lymphocytes
Immunology and Cell Biology - Tập 68 Số 2 - Trang 127-136 - 1990
D.L. Emery, J.S. Rothel, P.R. Wood
SummaryThe production of gamma‐interferon (γ‐IFN) and antigen‐specific immunoglobulin isotypes was monitored in sheep given primary and secondary inocula of protein and polysaccharide antigens with or without adjuvants. In efferent lymph from prefemoral nodes draining the site of inoculation, γ‐IFN levels increased within 24 h after injection of adjuvants Quill A, ...... hiện toàn bộ
THE REDUCTION OF NITRATE, NITRATE AND HYDROXYLAMINE BY E. COLI.
Immunology and Cell Biology - Tập 24 Số 3 - Trang 159-167 - 1946
June Lascelles, J.L. Still
PLASMA CLEARANCE AND DISTRIBUTION OF 125I‐OVINE PLACENTAL LACTOGEN IN SHEEP
Immunology and Cell Biology - Tập 61 Số 3 - Trang 301-311 - 1983
Surendranath Veeram Reddy, Watkins Wb
SummaryThe plasma clearance of 125I‐ovine placental lactogen (125I‐oPL) in pregnant, non‐pregnant and foetal sheep followed a biphasic exponential curve. The initial half‐life (t1(½)) of the hormone ranged from 5·7–12·7 min. The molecular identity of 125I‐oPL in plasma samples was e...... hiện toàn bộ
Cross‐talk between pro‐inflammatory transcription factors and glucocorticoids
Immunology and Cell Biology - Tập 79 Số 4 - Trang 376-384 - 2001
Ian M. Adcock, Gaetano Caramori
Asthma is a chronic inflammatory disease of the airway that is characterized by cellular infiltration and activation. These processes are induced by overexpression of chemokines and cytokines, such as eotaxin, IL‐1β and GM‐CSF. These mediators are downstream targets for the transcription factors activator protein‐1 (AP‐1) and nuclear factor‐κB (NF‐κB), which control the expression of most ...... hiện toàn bộ
In vitro induction of CD25+ CD4+ regulatory T cells by the neuropeptide alpha‐melanocyte stimulating hormone (α‐MSH)
Immunology and Cell Biology - Tập 79 Số 4 - Trang 358-367 - 2001
AW Taylor, Kenichi Namba
Recently, we have found that the neuropeptide alpha‐melanocyte stimulating hormone (α‐MSH) not only suppresses IFN‐γ production, but also induces TGF‐β1 production by activated effector T cells. These α‐MSH‐ treated effector T cells function as regulatory T cells in that they suppress IFN‐γ production and hypersensitivity mediated by other effector T cells. Experimental autoimmune uveoreti...... hiện toàn bộ
Reactive oxygen species are essential mediators in antigen presentation by Kupffer cells
Immunology and Cell Biology - Tập 83 Số 4 - Trang 336-343 - 2005
Kosei Maemura, Qizhi Zheng, Tatehiko Wada, Michitaka Ozaki, Sonshin Takao, Takashi Aikou, Gregory B. Bulkley, Andrew S. Klein, Zhaoli Sun
Kupffer cells (KC) act as APC in the liver and play a major role in the clearance of gut‐derived antigens and pathogens entering the liver with portal venous blood. Antigen presentation by KC has been implicated in regulation of the local and systemic immune responses. In this study, modulation of KC antigen presentation by antioxidants and the role of reactive oxygen species (ROS) as esse...... hiện toàn bộ
Structure, function and regulation of the Toll/IL‐1 receptor adaptor proteins
Immunology and Cell Biology - Tập 85 Số 6 - Trang 411-419 - 2007
Tanya M Watters, Elaine F. Kenny, Luke O'neill
The Toll/IL‐1 receptor (TIR) domain plays a central role in Toll‐like receptor (TLR) signalling. All TLRs contain a cytoplasmic TIR domain, which, upon activation, acts as a scaffold to recruit adaptor proteins. The adaptor proteins MyD88, Mal, TRIF, TRAM and SARM are also characterized by the presence of a TIR domain. MyD88, Mal, TRIF and TRAM associate with the TLRs via homophilic TIR do...... hiện toàn bộ
Perturbation of gut bacteria induces a coordinated cellular immune response in the purple sea urchin larva
Immunology and Cell Biology - Tập 95 Số 7 - Trang 647-647 - 2017
Eric Chun Hei Ho, Katherine M. Buckley, Catherine S. Schrankel, Nicholas W. Schuh, Taku Hibino, Cynthia M Solek, Koeun Bae, Guizhi Wang, Jonathan P. Rast
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