The identification and treatment of women with hyperglycaemia in pregnancy: an analysis of individual participant data, systematic reviews, meta-analyses and an economic evaluationHealth Technology Assessment - Tập 20 Số 86 - Trang 1-348
Diane Farrar, Mark Simmonds, Susan Griffin, Ana Duarte, Debbie A. Lawlor, Mark Sculpher, Lesley Smith, Su Golder, Derek Tuffnell, Martin Bland, Fidelma Dunne, Donald Whitelaw, John Wright, T. Sheldon
BackgroundGestational diabetes mellitus (GDM) is associated with a higher risk of important adverse outcomes. Practice varies and the best strategy for identifying and treating GDM is unclear.AimTo estimate the clinical effectiveness and cost-effectiveness of strategies...... hiện toàn bộ
Blood glucose self-monitoring in type 2 diabetes: a randomised controlled trialHealth Technology Assessment - Tập 13 Số 15
A J Farmer, Alisha N. Wade, David French, Judit Simon, P Yudkin, Alasdair Gray, Anthea Craven, L Goyder, Rury R. Holman, David Mant, A Kinmonth, A C Burden
Whole-body MRI compared with standard pathways for staging metastatic disease in lung and colorectal cancer: the Streamline diagnostic accuracy studiesHealth Technology Assessment - Tập 23 Số 66 - Trang 1-270
Stuart A. Taylor, Susan Mallett, Anne Miles, Stephen Morris, Laura Quinn, Caroline S. Clarke, Sandy Beare, John Bridgewater, Vicky Goh, Sam M. Janes, Dow‐Mu Koh, Alison J. Morton, Neal Navani, Alfred Oliver, Anwar R. Padhani, Shonit Punwani, Andrea Rockall, Steve Halligan
Background
Whole-body magnetic resonance imaging is advocated as an alternative to standard pathways for staging cancer.
Objectives
The objectives were to compare di...... hiện toàn bộ
Preoperative intravenous iron for anaemia in elective major open abdominal surgery: the PREVENTT RCTHealth Technology Assessment - Tập 25 Số 11 - Trang 1-58
Toby Richards, Ravishankar Rao Baikady, Ben Clevenger, Anna Butcher, Sandaruwani Abeysiri, Marisa Chau, Rebecca Swinson, Timothy Collier, Matthew Dodd, Laura Van Dyck, Iain C. Macdougall, Gavin J. Murphy, John Browne, Andrew W. Bradbury, A. A. Klein
Background
Anaemia affects 30–50% of patients before they undergo major surgery. Preoperative anaemia is associated with increased need for blood transfusion, postoperative complications and worse patient outcomes after surgery. International guidelines support the use of intravenous iron to correct anaemia...... hiện toàn bộ
Pre-hospital non-invasive ventilation for acute respiratory failure: a systematic review and cost-effectiveness evaluationHealth Technology Assessment - Tập 19 Số 42 - Trang 1-102
Abdullah Pandor, Praveen Thokala, Steve Goodacre, Edith Poku, John Stevens, Shijie Ren, Anna Cantrell, Gavin D. Perkins, Matt Ward, Jerry Penn-Ashman
BackgroundNon-invasive ventilation (NIV), in the form of continuous positive airway pressure (CPAP) or bilevel inspiratory positive airway pressure (BiPAP), is used in hospital to treat patients with acute respiratory failure. Pre-hospital NIV may be more effective than in-hospital NIV but requires additional ambulance service resources.... hiện toàn bộ
Pemetrexed for the maintenance treatment of locally advanced or metastatic non-small cell lung cancerHealth Technology Assessment - Tập 14 Số Suppl 2 - Trang 33-39
J Greenhalgh, C McLeod, A Bagust, Angela Boland, Nigel Fleeman, Y Dündar, J Oyee, Rumona Dickson, Helen Davis, J Green, Edward McKenna, M Pearson
This paper presents a summary of the evidence review group (ERG) report into the clinical effectiveness and cost-effectiveness of pemetrexed for the maintenance treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC), in accordance with the licensed indication, based upon the evidence submission from the manufacturer (Eli Lilly) to the National Institute for Health a...... hiện toàn bộ
Vitamin D supplementation to prevent acute respiratory infections: individual participant data meta-analysisHealth Technology Assessment - Tập 23 Số 2 - Trang 1-44
Adrian R. Martineau, David A. Jolliffe, Lauren Greenberg, John F. Aloia, Peter Bergman, Gal Dubnov‐Raz, Susanna Esposito, Davaasambuu Ganmaa, Adit A. Ginde, Emma C Goodall, Cameron Grant, Wim Janssens, Megan E. Jensen, Conor P. Kerley, Ilkka Laaksi, Semira Manaseki‐Holland, David T. Mauger, David R. Murdoch, Rachel Ε. Neale, Judy R. Rees, Steve Simpson, Iwona Stelmach, Geeta Trilok Kumar, Mitsuyoshi Urashima, Carlos A. Camargo, Chris Griffiths, Richard Hooper
Background
Randomised controlled trials (RCTs) exploring the potential of vitamin D to prevent acute respiratory infections have yielded mixed results. Individual participant data (IPD) meta-analysis has the potential to identify factors that may explain this heterogeneity.
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