The identification and treatment of women with hyperglycaemia in pregnancy: an analysis of individual participant data, systematic reviews, meta-analyses and an economic evaluationHealth Technology Assessment - Tập 20 Số 86 - Trang 1-348
Diane Farrar, Mark Simmonds, Susan Griffin, Ana Duarte, Debbie A. Lawlor, Mark Sculpher, Lesley Smith, Su Golder, Derek Tuffnell, Martin Bland, Fidelma Dunne, Donald Whitelaw, John Wright, T. Sheldon
BackgroundGestational diabetes mellitus (GDM) is associated with a higher risk
of important adverse outcomes. Practice varies and the best strategy for
identifying and treating GDM is unclear.AimTo estimate the clinical
effectiveness and cost-effectiveness of strategies for identifying and treating
women with GDM.MethodsWe analysed individual participant data (IPD) from birth
cohorts and conducted... hiện toàn bộ
Blood glucose self-monitoring in type 2 diabetes: a randomised controlled trialHealth Technology Assessment - Tập 13 Số 15
A J Farmer, Alisha N. Wade, David French, Judit Simon, P Yudkin, Alasdair Gray, Anthea Craven, L Goyder, Rury R. Holman, David Mant, A Kinmonth, A C Burden
Whole-body MRI compared with standard pathways for staging metastatic disease in lung and colorectal cancer: the Streamline diagnostic accuracy studiesHealth Technology Assessment - Tập 23 Số 66 - Trang 1-270
Stuart A. Taylor, Susan Mallett, Anne Miles, Stephen Morris, Laura Quinn, Caroline S. Clarke, Sandy Beare, John Bridgewater, Vicky Goh, Sam M. Janes, Dow‐Mu Koh, Alison J. Morton, Neal Navani, Alfred Oliver, Anwar R. Padhani, Shonit Punwani, Andrea Rockall, Steve Halligan
Background Whole-body magnetic resonance imaging is advocated as an alternative
to standard pathways for staging cancer. Objectives The objectives were to
compare diagnostic accuracy, efficiency, patient acceptability, observer
variability and cost-effectiveness of whole-body magnetic resonance imaging and
standard pathways in staging newly diagnosed non-small-cell lung cancer
(Streamline L) and c... hiện toàn bộ
Pre-hospital non-invasive ventilation for acute respiratory failure: a systematic review and cost-effectiveness evaluationHealth Technology Assessment - Tập 19 Số 42 - Trang 1-102
Abdullah Pandor, Praveen Thokala, Steve Goodacre, Edith Poku, John Stevens, Shijie Ren, Anna Cantrell, Gavin D. Perkins, Matt Ward, Jerry Penn-Ashman
BackgroundNon-invasive ventilation (NIV), in the form of continuous positive
airway pressure (CPAP) or bilevel inspiratory positive airway pressure (BiPAP),
is used in hospital to treat patients with acute respiratory failure.
Pre-hospital NIV may be more effective than in-hospital NIV but requires
additional ambulance service resources.ObjectivesWe aimed to determine the
clinical effectiveness an... hiện toàn bộ
Pemetrexed for the maintenance treatment of locally advanced or metastatic non-small cell lung cancerHealth Technology Assessment - Tập 14 Số Suppl 2 - Trang 33-39
J Greenhalgh, C McLeod, A Bagust, Angela Boland, Nigel Fleeman, Y Dündar, J Oyee, Rumona Dickson, Helen Davis, J Green, Edward McKenna, M Pearson
This paper presents a summary of the evidence review group (ERG) report into the
clinical effectiveness and cost-effectiveness of pemetrexed for the maintenance
treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC),
in accordance with the licensed indication, based upon the evidence submission
from the manufacturer (Eli Lilly) to the National Institute for Health and
Clini... hiện toàn bộ
Vitamin D supplementation to prevent acute respiratory infections: individual participant data meta-analysisHealth Technology Assessment - Tập 23 Số 2 - Trang 1-44
Adrian R. Martineau, David A. Jolliffe, Lauren Greenberg, John F. Aloia, Peter Bergman, Gal Dubnov‐Raz, Susanna Esposito, Davaasambuu Ganmaa, Adit A. Ginde, Emma C Goodall, Cameron Grant, Wim Janssens, Megan E. Jensen, Conor P. Kerley, Ilkka Laaksi, Semira Manaseki‐Holland, David T. Mauger, David R. Murdoch, Rachel Ε. Neale, Judy R. Rees, Steve Simpson, Iwona Stelmach, Geeta Trilok Kumar, Mitsuyoshi Urashima, Carlos A. Camargo, Chris Griffiths, Richard Hooper
Background Randomised controlled trials (RCTs) exploring the potential of
vitamin D to prevent acute respiratory infections have yielded mixed results.
Individual participant data (IPD) meta-analysis has the potential to identify
factors that may explain this heterogeneity. Objectives To assess the overall
effect of vitamin D supplementation on the risk of acute respiratory infections
(ARIs) and t... hiện toàn bộ