Mohammad Tauqeer Alam, Gregory C. A. Amos, Andrew Murphy, Simon Murch, Elizabeth M. H. Wellington, Ramesh P. Arasaradnam
Abstract Background Inflammatory bowel disease (IBD), is a debilitating group of
chronic diseases including Crohn’s Disease (CD) and ulcerative colitis (UC),
which causes inflammation of the gut and affects millions of people worldwide.
At different taxonomic levels, the structure of the gut microbiota is
significantly altered in IBD patients compared to that of healthy individuals.
However, it is... hiện toàn bộ
Manja Boehm, Benjamin Hoy, Manfred Rohde, Nicole Tegtmeyer, Kristoffer T. Bæk, Omar A. Oyarzábal, Lone Brøndsted, Silja Weßler, Steffen Backert
Abstract Background Campylobacter jejuni is one of the most important bacterial
pathogens causing food-borne illness worldwide. Crossing the intestinal
epithelial barrier and host cell entry by C. jejuni is considered the primary
reason of damage to the intestinal tissue, but the molecular mechanisms as well
as major bacterial and host cell factors involved in this process are still
widely unclear... hiện toàn bộ
Andrew Cunningham, Jeffrey W. Stephens, David A. Harris
AbstractA strong and expanding evidence base supports the influence of gut
microbiota in human metabolism. Altered glucose homeostasis is associated with
altered gut microbiota, and is clearly associated with the development of type 2
diabetes mellitus (T2DM) and associated complications. Understanding the causal
association between gut microbiota and metabolic risk has the potential role of
ident... hiện toàn bộ
Alison C. Bested, Alan C. Logan, Eva Michelle Selhub
Abstract In recent years there has been a renewed interest concerning the ways
in which the gastrointestinal tract – its functional integrity and microbial
residents – might influence human mood (e.g. depression) and behavioral
disorders. Once a hotbed of scientific interest in the early 20th century, this
area lay dormant for decades, in part due to its association with the
controversial term ‘au... hiện toàn bộ
Abstract Background Personal Protective Equipment (PPE) is required to safely
work with biological agents of bacterial (i.e. Mycobacterium tuberculosis) or
viral origin (Ebola and SARS). COVID-19 pandemic especially has created
unforeseen public health challenges including a global shortage of PPE needed
for the safety of health care workers (HCWs). Although sufficient stocks of PPE
are currently ... hiện toàn bộ
Abstract Background homB encodes a Helicobacter pylori outer membrane protein.
This gene was previously associated with peptic ulcer disease (PUD) and was
shown to induce activation of interleukin-8 secretion in vitro, as well as
contributing to bacterial adherence. Its 90%-similar gene, homA, was previously
correlated with gastritis. The present study aimed to evaluate the gastric
disease associa... hiện toàn bộ