Glycoconjugate Journal

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Glycosyltransferases in SWISS-PROT
Glycoconjugate Journal - Tập 15 - Trang 507-509 - 1998
Claire O'Donovan, Nicoletta Mitaritonna
SWISS-PROT is a curated protein sequence database with a high level of annotation (such as description of the function of a protein, its domain structure, post-translational modification, variants, etc), a minimal level of redundancy and a high level of integration with other databases. An ongoing project is to maintain the glycosyltransferase family of enzymes with comprehensive annotation and do...... hiện toàn bộ
Elevated expression of L-selectin ligand in lymph node-derived human prostate cancer cells correlates with increased tumorigenicity
Glycoconjugate Journal - Tập 26 Số 1 - Trang 75-81 - 2009
Prakash Radhakrishnan, Ming‐Fong Lin, Pi-Wan Cheng
Benchmark of site- and structure-specific quantitative tissue N-glycoproteomics for discovery of potential N-glycoprotein markers: a case study of pancreatic cancer
Glycoconjugate Journal - Tập 38 - Trang 213-231 - 2021
Haoran Lu, Kaijie Xiao, Zhixin Tian
Pancreatic cancer is a highly malignant tumor of the digestive tract that is difficult to diagnose and treat. It is more common in developed countries and has become one of the main causes of death in some countries and regions. Currently, pancreatic cancer generally has a poor prognosis, partly due to the lack of symptoms in the early stages of pancreatic cancer. Therefore, most cases are diagnos...... hiện toàn bộ
Identification by mass spectrometry and immunoblotting of xenogeneic antigens in the N- and O-glycomes of porcine, bovine and equine heart tissues
Glycoconjugate Journal - Tập 37 - Trang 485-498 - 2020
Chunsheng Jin, Reeja Maria Cherian, Jining Liu, Heribert Playà-Albinyana, Cesare Galli, Niclas G. Karlsson, Michael E. Breimer, Jan Holgersson
Animal bioprosthetic heart valves (BHV) are used to replace defective valves in patients with valvular heart disease. Especially young BHV recipients may experience a structural valve deterioration caused by an immune reaction in which α-Gal and Neu5Gc are potential target antigens. The expression of these and other carbohydrate antigens in animal tissues used for production of BHV was explored. P...... hiện toàn bộ
Correlation between the sialylation of cell surface Thomsen-Friedenreich antigen and the metastatic potential of colon carcinoma cells in a mouse model
Glycoconjugate Journal - - 2001
Yoko Nemoto-Sasaki, Motoaki Mitsuki, Megumi Morimoto-Tomita, Azusa Maeda, Makoto Tsuiji, Tatsuro Irimura
The cell surface glycosylation profiles of a liver metastatic colon carcinoma variant cell line, SL4 cells previously selected from colon 38 cells in vivo for liver colonization were investigated. Flowcytometric analysis was performed with 7 plant lectins and 10 carbohydrate specific monoclonal antibodies. The results showed that peanut agglutinin (PNA), Sambucus nigra agglutinin, Ulex europeus ag...... hiện toàn bộ
S1.16N-glycan patterns and GlcNAc — Transferase I activities of three insect cell lines
Glycoconjugate Journal - Tập 10 - Trang 224-225 - 1993
V. Kubelka, F. Altmann, G. Kornfeld, V. Tretter, E. Staudacher, L. März, J. Glössl
Influence of phospholipid chain length on verotoxin/globotriaosyl ceramide binding in model membranes: comparison of a supported bilayer film and liposomes
Glycoconjugate Journal - Tập 13 - Trang 159-166 - 1996
Sara Arab, Clifford A. Lingwood
The importance of the surrounding lipid environment on the availability of glycolipid carbohydrate for ligand binding was demonstrated by studying the influence of phosphatidylcholine fatty acid chain length on binding of verotoxins (VT1 and VT2c) to their specific cell surface receptor, globotriaosylceramide (Gb3) in the presence of auxiliary lipids both in a microtitre plate surface bilayer film...... hiện toàn bộ
Preparation of antisera to recombinant, solubleN-acetylglucosaminyltransferase V and its visualizationin situ
Glycoconjugate Journal - Tập 12 - Trang 813-823 - 1995
Lin Chen, Ning Zhang, Beverly Adler, Jeffery Browne, Nevis Freigen, Michael Pierce
N-Acetylglucosaminyltransferase V (GlcNAc-T V) is a glycosyltransferase which transfersN-acetylglucosamine in β(1,6) linkage to the α(1,6)-linked mannose residue of Asn-linked oligosaccharides. This enzyme is characterized by several unusual properties: GlcNAc-T V is the largest lumenal Golgi glycosyltransferase described thus far, and its multiple mRNA transcripts range from 4.5 to about 9.5 kb;...... hiện toàn bộ
In vivo kinetics and biodistribution analysis of neoglycoproteins: effects of chemically introduced glycans on proteins
Glycoconjugate Journal - Tập 31 - Trang 273-279 - 2014
Akihiro Ogura, Almira Kurbangalieva, Katsunori Tanaka
Biodistribution and in vivo kinetics analysis of chemically prepared neoglycoproteins are reviewed. Various mono- and oligosaccharides were conjugated onto the protein surface by use of chemical methods. Their kinetic and organ-specific accumulation have extensively been studied after intravenous injection and analyzed by conventional dissection studies, as well as noninvasive methods, such as SPE...... hiện toàn bộ
Use of a novel anti-proliferative compound coated on a biopolymer to mitigate platelet-derived growth factor-induced proliferation in human aortic smooth muscle cells: comparison with sirolimus
Glycoconjugate Journal - Tập 26 - Trang 721-732 - 2008
Yong-Dan Tang, Ambarish Pandey, Antonina Kolmakova, Xin-Tong Wang, Subbu S. Venkatraman, Subroto Chatterjee, Freddy Y. C. Boey
Drug eluting stents (DES) have become a common mode of treatment for stenosis in coronary arteries. However, currently, the use of sirolimus/paclitaxel-coated DES has come under scrutiny, because of their pro-thrombotic effects leading to potential adverse outcomes in the long run. We have previously documented that d-threo-1-phenyl-2-decanoylamino-3-morholino propanol (D-PDMP); an inhibitor of gl...... hiện toàn bộ
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