Glycosyltransferases in SWISS-PROTGlycoconjugate Journal - Tập 15 - Trang 507-509 - 1998
Claire O'Donovan, Nicoletta Mitaritonna
SWISS-PROT is a curated protein sequence database with a high level of annotation (such as description of the function of a protein, its domain structure, post-translational modification, variants, etc), a minimal level of redundancy and a high level of integration with other databases. An ongoing project is to maintain the glycosyltransferase family of enzymes with comprehensive annotation and do...... hiện toàn bộ
Identification by mass spectrometry and immunoblotting of xenogeneic antigens in the N- and O-glycomes of porcine, bovine and equine heart tissuesGlycoconjugate Journal - Tập 37 - Trang 485-498 - 2020
Chunsheng Jin, Reeja Maria Cherian, Jining Liu, Heribert Playà-Albinyana, Cesare Galli, Niclas G. Karlsson, Michael E. Breimer, Jan Holgersson
Animal bioprosthetic heart valves (BHV) are used to replace defective valves in patients with valvular heart disease. Especially young BHV recipients may experience a structural valve deterioration caused by an immune reaction in which α-Gal and Neu5Gc are potential target antigens. The expression of these and other carbohydrate antigens in animal tissues used for production of BHV was explored. P...... hiện toàn bộ
Preparation of antisera to recombinant, solubleN-acetylglucosaminyltransferase V and its visualizationin situGlycoconjugate Journal - Tập 12 - Trang 813-823 - 1995
Lin Chen, Ning Zhang, Beverly Adler, Jeffery Browne, Nevis Freigen, Michael Pierce
N-Acetylglucosaminyltransferase V (GlcNAc-T V) is a glycosyltransferase which transfersN-acetylglucosamine in β(1,6) linkage to the α(1,6)-linked mannose residue of Asn-linked oligosaccharides. This enzyme is characterized by several unusual properties: GlcNAc-T V is the largest lumenal Golgi glycosyltransferase described thus far, and its multiple mRNA transcripts range from 4.5 to about 9.5 kb;...... hiện toàn bộ
In vivo kinetics and biodistribution analysis of neoglycoproteins: effects of chemically introduced glycans on proteinsGlycoconjugate Journal - Tập 31 - Trang 273-279 - 2014
Akihiro Ogura, Almira Kurbangalieva, Katsunori Tanaka
Biodistribution and in vivo kinetics analysis of chemically prepared neoglycoproteins are reviewed. Various mono- and oligosaccharides were conjugated onto the protein surface by use of chemical methods. Their kinetic and organ-specific accumulation have extensively been studied after intravenous injection and analyzed by conventional dissection studies, as well as noninvasive methods, such as SPE...... hiện toàn bộ