Glycoconjugate Journal
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Glycosyltransferases in SWISS-PROT
Glycoconjugate Journal - Tập 15 - Trang 507-509 - 1998
SWISS-PROT is a curated protein sequence database with a high level of
annotation (such as description of the function of a protein, its domain
structure, post-translational modification, variants, etc), a minimal level of
redundancy and a high level of integration with other databases. An ongoing
project is to maintain the glycosyltransferase family of enzymes with
comprehensive annotation and do...
Elevated expression of L-selectin ligand in lymph node-derived human prostate cancer cells correlates with increased tumorigenicity
Glycoconjugate Journal - Tập 26 Số 1 - Trang 75-81 - 2009
Benchmark of site- and structure-specific quantitative tissue N-glycoproteomics for discovery of potential N-glycoprotein markers: a case study of pancreatic cancer
Glycoconjugate Journal - Tập 38 - Trang 213-231 - 2021
Pancreatic cancer is a highly malignant tumor of the digestive tract that is
difficult to diagnose and treat. It is more common in developed countries and
has become one of the main causes of death in some countries and regions.
Currently, pancreatic cancer generally has a poor prognosis, partly due to the
lack of symptoms in the early stages of pancreatic cancer. Therefore, most cases
are diagnos...
Identification by mass spectrometry and immunoblotting of xenogeneic antigens in the N- and O-glycomes of porcine, bovine and equine heart tissues
Glycoconjugate Journal - Tập 37 - Trang 485-498 - 2020
Animal bioprosthetic heart valves (BHV) are used to replace defective valves in
patients with valvular heart disease. Especially young BHV recipients may
experience a structural valve deterioration caused by an immune reaction in
which α-Gal and Neu5Gc are potential target antigens. The expression of these
and other carbohydrate antigens in animal tissues used for production of BHV was
explored. P...
Correlation between the sialylation of cell surface Thomsen-Friedenreich antigen and the metastatic potential of colon carcinoma cells in a mouse model
Glycoconjugate Journal - - 2001
The cell surface glycosylation profiles of a liver metastatic colon carcinoma
variant cell line, SL4 cells previously selected from colon 38 cells in vivo for
liver colonization were investigated. Flowcytometric analysis was performed with
7 plant lectins and 10 carbohydrate specific monoclonal antibodies. The results
showed that peanut agglutinin (PNA), Sambucus nigra agglutinin, Ulex europeus
ag...
S1.16N-glycan patterns and GlcNAc — Transferase I activities of three insect cell lines
Glycoconjugate Journal - Tập 10 - Trang 224-225 - 1993
Influence of phospholipid chain length on verotoxin/globotriaosyl ceramide binding in model membranes: comparison of a supported bilayer film and liposomes
Glycoconjugate Journal - Tập 13 - Trang 159-166 - 1996
The importance of the surrounding lipid environment on the availability of
glycolipid carbohydrate for ligand binding was demonstrated by studying the
influence of phosphatidylcholine fatty acid chain length on binding of
verotoxins (VT1 and VT2c) to their specific cell surface receptor,
globotriaosylceramide (Gb3) in the presence of auxiliary lipids both in a
microtitre plate surface bilayer film...
Preparation of antisera to recombinant, solubleN-acetylglucosaminyltransferase V and its visualizationin situ
Glycoconjugate Journal - Tập 12 - Trang 813-823 - 1995
N-Acetylglucosaminyltransferase V (GlcNAc-T V) is a glycosyltransferase which
transfersN-acetylglucosamine in β(1,6) linkage to the α(1,6)-linked mannose
residue of Asn-linked oligosaccharides. This enzyme is characterized by several
unusual properties: GlcNAc-T V is the largest lumenal Golgi glycosyltransferase
described thus far, and its multiple mRNA transcripts range from 4.5 to about
9.5 kb; ...
In vivo kinetics and biodistribution analysis of neoglycoproteins: effects of chemically introduced glycans on proteins
Glycoconjugate Journal - Tập 31 - Trang 273-279 - 2014
Biodistribution and in vivo kinetics analysis of chemically prepared
neoglycoproteins are reviewed. Various mono- and oligosaccharides were
conjugated onto the protein surface by use of chemical methods. Their kinetic
and organ-specific accumulation have extensively been studied after intravenous
injection and analyzed by conventional dissection studies, as well as
noninvasive methods, such as SPE...
Use of a novel anti-proliferative compound coated on a biopolymer to mitigate platelet-derived growth factor-induced proliferation in human aortic smooth muscle cells: comparison with sirolimus
Glycoconjugate Journal - Tập 26 - Trang 721-732 - 2008
Drug eluting stents (DES) have become a common mode of treatment for stenosis in
coronary arteries. However, currently, the use of sirolimus/paclitaxel-coated
DES has come under scrutiny, because of their pro-thrombotic effects leading to
potential adverse outcomes in the long run. We have previously documented that
d-threo-1-phenyl-2-decanoylamino-3-morholino propanol (D-PDMP); an inhibitor of
gl...
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