Genetical Research
SCIE-ISI SCOPUS (1960-2024)
0016-6723
1469-5073
Anh Quốc
Cơ quản chủ quản: Cambridge University Press , HINDAWI LTD
Lĩnh vực:
GeneticsMedicine (miscellaneous)
Các bài báo tiêu biểu
A mechanism for gene conversion in fungi
Tập 5 Số 2 - Trang 282-304 - 1964
A mechanism for gene conversion is proposed which overcomes many of the
difficulties that any copy choice model encounters. It is suggested that along
with general genetic pairing of homologous genomes at meiosis, effective pairing
over short regions of the genetic material occurs at the molecular level by the
separation of the strands of the DNA double helices, followed by the annealing
of strand...
Effective population size/adult population size ratios in wildlife: a review
Tập 66 Số 2 - Trang 95-107 - 1995
SummaryThe effective population size is required to predict the rate of
inbreeding and loss of genetic variation in wildlife. Since only census
population size is normally available, it is critical to know the ratio of
effective to actual population size (Ne/N). Published estimates ofNe/N(192 from
102 species) were analysed to identify major variables affecting the ratio, and
to obtain a comprehen...
Estimators for pairwise relatedness and individual inbreeding coefficients
Tập 67 Số 2 - Trang 175-185 - 1996
SummaryMethod-of-moments estimators (MMEs) for the two-gene coefficients of
relationship and inbreeding, and for thxe four-gene Cotterman coefficients, are
described. These estimators, which use co-dominant genetic markers, are most
appropriate for estimating pairwise relatedness or individual inbreeding
coefficients, as opposed to their mean values in a group. This is because,
compared to the max...
Statistical design and the analysis of gene expression microarray data
Tập 77 Số 2 - Trang 123-128 - 2001
Gene expression microarrays are an innovative technology with enormous promise
to help geneticists explore and understand the genome. Although the potential of
this technology has been clearly demonstrated, many important and interesting
statistical questions persist. We relate certain features of microarrays to
other kinds of experimental data and argue that classical statistical techniques
are a...
Triadic IBD coefficients and applications to estimating pairwise relatedness
Tập 89 Số 3 - Trang 135-153 - 2007
SummaryKnowledge of the genetic relatedness among individuals is essential in
diverse research areas such as behavioural ecology, conservation biology,
quantitative genetics and forensics. How to estimate relatedness accurately from
genetic marker information has been explored recently by many methodological
studies. In this investigation I propose a new likelihood method that uses the
genotypes o...
Inbreeding in artificial selection programmes
Tập 2 Số 2 - Trang 189-194 - 1961
In a population under artificial selection, the effective population size may be
less than the actual number of parents selected because there will be variation
between families in the character under selection and consequently in the
probability of selection. Expressions are developed for the magnitude of the
effect, which will be greater the more intense the selection and the higher the
heritabi...
Phylogeography of Aedes (Stegomyia) aegypti (L.) and Aedes (Stegomyia) albopictus (Skuse) (Diptera: Culicidae) based on mitochondrial DNA variations
Tập 86 Số 1 - Trang 1-11 - 2005
Aedes (Stegomyia) aegypti (L.) and Aedes (Stegomyia) albopictus (Skuse) are the
most important vectors of the dengue and yellow-fever viruses. Both took
advantage of trade developments to spread throughout the tropics from their
native area: A. aegypti originated from Africa and A. albopictus from South-East
Asia. We investigated the relationships between A. aegypti and A. albopictus
mosquitoes ba...
The use ofp-fluorophenylalanine with ‘master strains’ ofAspergillus nidulansfor assigning genes to linkage groups
Tập 6 Số 3 - Trang 352-359 - 1965
Four ‘master’ strains ofAspergillus nidulans, three of which are marked on each
of the eight chromosomes, are used for assigning genes of unknown location to
linkage groups. In this technique a heterozygous diploid is synthesized between
one ‘master’ strain and a strain carrying an unlocated marker. This diploid is
haploidized by growth onp-fluorophenylalanine, and the haploids thus obtained
are c...
Polymorphism in a varied environment: how robust are the models?
Tập 35 Số 1 - Trang 45-57 - 1980
SUMMARYThis paper shows that a number of models of the maintenance of
polymorphism in a heterogeneous environment, including those of Levene and
Dempster, can be derived from a simple assumption about the way in which the
numbers and kinds of individuals emerging from a niche depend on the number of
eggs laid in it. It is shown that for such models, unless selective advantages
per locus are large,...
The distribution of the fraction of the genome identical by descent in finite random mating populations
Tập 35 Số 2 - Trang 131-155 - 1980
SUMMARYThe probability distribution of the heterogenic (non-identical by
descent) fraction of the genome in a finite monoecious random mating population
has been derived. It was assumed that in any generation the length of both
heterogenic and homogenic segments are exponentially distributed. An explicit
expression is given for the expected number of ‘external junctions’ (sites that
mark the end o...