Genesis
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Embryological development of Caiman latirostris (Crocodylia: Alligatoridae)Abstract A standard development embryological series is the primary basis to organize information of any embryological study and is also used to determine the age of eggs and embryos in field conditions. In this article, we calibrate developmental series of the broad‐snouted caiman, Caiman latirostris , against an established series for ... hiện toàn bộ
Genesis - Tập 46 Số 8 - Trang 401-417 - 2008
In vivo genetic ablation by Cre-mediated expression of diphtheria toxin fragment A
Genesis - Tập 43 Số 3 - Trang 129-135 - 2005
Dll1 is a downstream target of Tbx6 in the paraxial mesoderm
Genesis - Tập 42 Số 3 - Trang 193-202 - 2005
vavCre Transgenic mice: A tool for mutagenesis in hematopoietic and endothelial lineagesAbstract Summary: Cre transgenic mice can be used to delete gene sequences flanked by loxP sites in specific somatic tissues. We have generated vavCre transgenic mice, which can be used to inactivate genes specifically in adult hematopoietic and endothelial cells. In these animals, a ... hiện toàn bộ
Genesis - Tập 34 Số 4 - Trang 251-256 - 2002
Splice‐activated UAS hairpin vector gives complete RNAi knockout of single or double target transcripts in drosophila melanogaster
Genesis - Tập 34 Số 1-2 - Trang 160-164 - 2002
Generation of Pax2‐Cre mice by modification of a Pax2 bacterial artificial chromosomeAbstract Summary: The Pax2 gene is expressed in the developing otocyst, kidney, and midbrain–hindbrain boundary. We generated Pax2‐Cre transgenic lines by modification of a Pax2 bacterial artificial chromosome (BAC). In one Pax2‐Cre line, Cre mRNA starts to be expressed in the otic placode at the late presomite stage. R26R reporter mouse analysis revealed that the C... ... hiện toàn bộ
Genesis - Tập 38 Số 4 - Trang 195-199 - 2004
A fate map of Tbx1 expressing cells reveals heterogeneity in the second cardiac fieldAbstract Tbx1 is required for the expansion of second heart field (SHF) cardiac progenitors destined to the outflow tract of the heart. Loss of Tbx1 causes heart defects in humans and mice. We report a novel Tbx1Cre knock‐in allele that we use to fate map ... hiện toàn bộ
Genesis - Tập 45 Số 7 - Trang 470-475 - 2007
Gain of function of Tbx1 affects pharyngeal and heart development in the mouseAbstract Mammalian development is highly sensitive to Tbx1 gene dosage reduction. Gene function insights can also be learned from increased or ectopic expression. The authors generated a novel mouse transgenic line, named COET, which expresses Tbx1 upon Cre‐mediated recombination. The authors crossed this transge... ... hiện toàn bộ
Genesis - Tập 47 Số 3 - Trang 188-195 - 2009
GABAergic neurons regulate lateral ventricular development via transcription factor Pax5Summary Postmortem studies have revealed a downregulation of the transcription factor Pax5 in GABAergic neurons in bipolar disorder, a neurodevelopmental disorder, raising the question whether Pax5 in GABAergic neurons has a role in normal brain development. In a genetic approach to study functions of ... hiện toàn bộ
Genesis - Tập 51 Số 4 - Trang 234-245 - 2013
Long‐range effect of upd, a ligand for Jak/STAT pathway, on cell cycle in Drosophila eye developmentAbstract unpaired (upd ) encodes a ligand for the Jak/STAT signaling pathway in Drosophila . In the second instar and early third larval eye disc, upd is expressed in the center of the posterior margin. upd loss‐of‐function mutations c...
Genesis - Tập 39 Số 2 - Trang 141-153 - 2004
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