Gastroenterologia Japonica

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Ramucirumab as second-line treatment in patients with advanced hepatocellular carcinoma: Japanese subgroup analysis of the REACH trial
Gastroenterologia Japonica - Tập 52 - Trang 494-503 - 2016
Masatoshi Kudo, Etsuro Hatano, Shinichi Ohkawa, Hirofumi Fujii, Akihide Masumoto, Junji Furuse, Yoshiyuki Wada, Hiroshi Ishii, Shuntaro Obi, Shuichi Kaneko, Seiji Kawazoe, Osamu Yokosuka, Masafumi Ikeda, Katsuaki Ukai, Sojiro Morita, Akihito Tsuji, Toshihiro Kudo, Mitsuo Shimada, Yukio Osaki, Ryosuke Tateishi, Gen Sugiyama, Paolo Benjamin Abada, Ling Yang, Takuji Okusaka, Andrew Xiuxuan Zhu
REACH evaluated ramucirumab in the second-line treatment of patients with advanced hepatocellular carcinoma. In the intent-to-treat population (n = 565), a significant improvement in overall survival (OS) was not observed. In patients with an elevated baseline α-fetoprotein (AFP) level (400 ng/mL or greater), an improvement in OS was demonstrated. An analysis of the Japanese patients in REACH was ...... hiện toàn bộ
Experimental and bioinformatics comparison of gene expression between T cells from TIL of liver cancer and T cells from UniGene
Gastroenterologia Japonica - Tập 37 - Trang 275-282 - 2002
Biaoru Li, Supriya Perabekam, Ge Liu, Mei Yin, Shiwen Song, Alan Larson
The major difficulty of mapping parallel gene expression obtained from solid tumors is mainly due to contaminating cells. In this study, by applying a strategy of parallel gene expression at a cell-cluster or colony level, we have identified the gene expression pattern of T cells within tumor-infiltrating lymphocytes (TILs) obtained from two liver cancer patients. Methods. Here a new method was u...... hiện toàn bộ
Studies of experimental peptic ulcer In relation to arteriosclerosis
Gastroenterologia Japonica - Tập 3 - Trang 163-163 - 1968
K. Mori, T. Tamada, K. Inoue, H. Ebira
Detection of Ki-ras and p53 gene mutations in tissue and pancreatic juice from pancreatic adenocarcinomas
Gastroenterologia Japonica - Tập 33 - Trang 390-396 - 1998
Satoshi Kondoh, Miyuki Kaino, Satoshi Okita, Syomei Ryozawa, Tetsuji Akiyama, Kiwamu Okita
Pancreatic carcinomas have a high incidence of Ki-ras mutations, and the genetic change is thought to occur at an early stage in the carcinogenesis. The aim of this study was to evaluate the usefulness of detecting genetic mutations in pure pancreatic juice (PPJ). DNA was extracted from tissue specimens of pancreatic carcinomas and from cells in PPJ, and subjected to polymerase chain reaction-sin...... hiện toàn bộ
Clinical study of tolbutamaid test in liver disease
Gastroenterologia Japonica - Tập 2 - Trang 137-138 - 1967
K. Ariga, M. Hase, M. Okabe, H. Kurihara
Genetic changes in colorectal adenoma and cancer in relation to various morphologic aspects
Gastroenterologia Japonica - Tập 33 - Trang 804-810 - 1998
Takahiro Fujimori, Yuko Ono, Kazuhiro Sakuma, Yoshihiko Ueda, Akira Terano
Serum carboxypeptidase—b activity in various liver diseases
Gastroenterologia Japonica - Tập 2 - Trang 360-360 - 1967
M. Murakami, O. Ohara, Y. Yagi, I. Kawagishi, C. Kitashima, K. Hirasawa, K. Shinozaki
Leucocyte adherence inhibition assay for cell-mediated immunity and immunodiagnosis of pancreatic cancer
Gastroenterologia Japonica - Tập 19 - Trang 328-335 - 1984
Morikazu Onji
The present study was conducted to determine whether the leucocyte adherence inhibition (LAI) assay was dependent on cell-mediated immunity and whether it was of potential use in diagnosis of pancreatic cancer. The LAI response was significantly positive in 15 PPD skin-test positive individuals but it was abated by pretreatment of sensitized mononuclear cells with anti-T cell antibody (OKT3) or by...... hiện toàn bộ
Studies on the gastric ulcer in the aged
Gastroenterologia Japonica - Tập 7 - Trang 358-359 - 1972
Y. Nakata, J. Yamashita, M. Tsuda, M. Iwamoto, A. Sakai
Development of reflux esophagitis following Helicobacter pylori eradication
Gastroenterologia Japonica - Tập 40 - Trang 1024-1028 - 2005
Masahiro Kawanishi
We aimed to determine the incidence and causative factors of reflux esophagitis following Helicobacter pylori eradication in Japanese patients. In patients in whom reflux esophagitis could not be detected endoscopically, we conducted an annual follow-up observation in 326 H. pylori-cured patients, 199 H. pylori-positive patients, and 151 H. pylori-negative patients, to study the incidence and caus...... hiện toàn bộ
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