Long-Term Treatment With Letrozole in a Boy With Familial Male-Limited Precocious PubertyFrontiers in Endocrinology - Tập 13
Xin Yuan, Ruimin Chen, Ying Zhang, Xiaohong Yang, Xiaoqin Lin
BackgroundThe long-term follow-up in children with familial male-limited precocious puberty (FMPP) who were treated with letrozole, triptorelin, and spironolactone is limited, especially considering the efficiency and safety.ObjectiveWe describe the clinical characteristics and long-term treat...... hiện toàn bộ
Tmod3 Phosphorylation Mediates AMPK-Dependent GLUT4 Plasma Membrane Insertion in MyoblastsFrontiers in Endocrinology - Tập 12
Man Mohan Shrestha, Chun Yan Lim, Xuezhi Bi, Robert Robinson, Weiping Han
Insulin and muscle contractions mediate glucose transporter 4 (GLUT4) translocation and insertion into the plasma membrane (PM) for glucose uptake in skeletal muscles. Muscle contraction results in AMPK activation, which promotes GLUT4 translocation and PM insertion. However, little is known regarding AMPK effectors that directly regulate GLUT4 translocation. We aim to identify novel AMPK ...... hiện toàn bộ