AbstractFollowing improvement and integration of novel genome sequencing
techniques, a new stage light has been shone upon circular RNAs (circRNA) in
regard to their structure and functionality. In comparison to their linear
counterparts, circRNA possess a multitude of remarkable functions such as
microRNA (miRNA) sponging, RNA-binding protein (RBP) regulation and
translational capabilities whose ... hiện toàn bộ
Abstract MicroRNAs (miRNAs) are a number of small non-coding RNAs playing a
regulatory part in gene expression. Many virus-encoded miRNAs have been found,
which manifests that viruses as well apply the basic pattern of gene regulation,
however, mostly in viruses transcribed from double-stranded DNA genomes. It is
still in dispute if RNA viruses could encode miRNAs because the excision of
miRNA mig... hiện toàn bộ
Abstract Background Bovine milk exosomes are studied for their roles as
bioactive food compounds and as vehicles for drug delivery. Both lines of
investigation converge on immune function, e.g., immune regulation by absorption
of microRNAs encapsulated in milk exosomes across species boundaries, and the
possibility of exosomes and their cargos triggering an immune response if used
in drug delivery... hiện toàn bộ
M. Shoff, Timberly Booker, Blair R. Leavitt, David C. Harmon, Karl Kingsley, Katherine M. Howard
Abstract Background Oral squamous cell carcinomas (OSCC) secrete exosomes into
the surrounding extracellular environment to promote the horizontal transfer of
bioactive molecules including microRNA (miRNA). The primary objective of this
study was to explore potential differences in miRNA content between OSCC and
OSCC stem cells. Methods The OSCC cell lines SCC4, SCC15, SCC25 and CAL27 were
used in... hiện toàn bộ
Abstract Procambarus clarkii is one of the important economic species in China
and has been served as tasty food in recent years after being introduced to
Nanjing. Significant problems of environment factors, such as salinity, pH and
temperature, especially salinity, has the potential to result in significant
economic losses in many crayfish-producing farms in China. miRNAs are a kind of
~ 22 nucl... hiện toàn bộ
Liangsheng Lu, Yuan Liu, Yuyan Liu, Fan Zhang, Han Wang, Qipeng Zhang, Feng Pan
microRNAs are small, non-coding, single-stranded RNAs that can suppress mRNA
translation at the posttranscriptional level by binding to imperfect
complementary sequences on mRNA targets and then cause their degradation or
hinder protein translation. Recently, bunch of evidence showed that microRNAs
(miRNAs) existed in presynaptic and postsynaptic parts and implicated in the
synapses formation and ... hiện toàn bộ
Houttuynia cordata Thunb (Family: Saururaceae) is well known as a traditional
medicine plant and widely spread in China, Japan and India. It had been reported
to have potential functions such as anti-bacterial, anti-cancer, and
anti-inflammatory in human. Recently, it has been reported that the
plant-derived microRNA(miRNA) possibly transported from one species to another
and exerted a cross kingd... hiện toàn bộ