Management of adrenal incidentalomas: European Society of Endocrinology Clinical Practice Guideline in collaboration with the European Network for the Study of Adrenal Tumors Tập 175 Số 2 - Trang G1-G34 - 2016
Martin Faßnacht, Wiebke Arlt, Irina Bancos, Henning Dralle, John Newell‐Price, Anju Sahdev, Antoine Tabarin, Massimo Terzolo, Stylianos Tsagarakis, Olaf M. Dekkers
By definition, an adrenal incidentaloma is an asymptomatic adrenal mass detected
on imaging not performed for suspected adrenal disease. In most cases, adrenal
incidentalomas are nonfunctioning adrenocortical adenomas, but may also
represent conditions requiring therapeutic intervention (e.g. adrenocortical
carcinoma, pheochromocytoma, hormone-producing adenoma or metastasis). The
purpose of this ... hiện toàn bộ
Pathohistological classification of pituitary tumors: 10 years of experience with the German Pituitary Tumor Registry Tập 156 Số 2 - Trang 203-216 - 2007
Wolfgang Saeger, Dieter K. Lüdecke, Michael Buchfelder, Rudolf Fahlbusch, Hans-Jürgen Quabbe, Stephan Petersenn
In 1996, the German Registry of Pituitary Tumors was founded by the Pituitary
Section of the German Society of Endocrinology as a reference center for
collection and consultant pathohistological studies of pituitary tumors. The
experiences of the first 10 years of this registry based on 4122 cases will
herein be reported. The data supplement former collections of the years
1970–1995 with 3480 surg... hiện toàn bộ
Neurosteroid metabolism in the human brain - Trang 669-679 - 2001
Birgit Stoffel‐Wagner
This review summarizes the current knowledge of the biosynthesis of
neurosteroids in the human brain, the enzymes mediating these reactions, their
localization and the putative effects of neurosteroids. Molecular biological and
biochemical studies have now firmly established the presence of the
steroidogenic enzymes cytochrome P450 cholesterol side-chain cleavage (P450SCC),
aromatase, 5alpha-reduc... hiện toàn bộ
Insulin-like growth factors I and II in healthy man. Tập 121 Số 6 - Trang 753-758 - 1989
Hans‐Peter Guler, Jürgen Zapf, Christoph Schmid, E. R. Froesch
Abstract. IGF-I and -II share specific serum carrier proteins which elute on
neutral Sephadex G-200 gel permeation chromatography at apparent molecular
masses of 50 and 200 kD. The half-lives of free and carrier protein-bound
125I-IGF-I and -II were determined after bolus injections of the tracers into
two normal adults. Labelled IGF-I and -II migrated first with the 50-kD and
later with the 200-k... hiện toàn bộ
Glucocorticoids and Cardiovascular Disease Tập 157 Số 5 - Trang 545-559 - 2007
Brian R. Walker
AbstractChronic excessive activation of glucocorticoid receptors induces
obesity, insulin resistance, glucose intolerance, dyslipidaemia and
hypertension. Subtle abnormalities of the hypothalamic–pituitary–adrenal axis
and/or of tissue sensitivity to glucocorticoids are also associated with these
cardiovascular risk factors in patients with the metabolic syndrome.
Furthermore, glucocorticoids have... hiện toàn bộ
The outcome of surgery in 668 patients with acromegaly using current criteria of biochemical ‘cure’ Tập 152 Số 3 - Trang 379-387 - 2005
P. Nomikos, Michael Buchfelder, Rudolf Fahlbusch
Background and aim: The aim of this study was to illustrate the present role of
transsphenoidal surgery as primary therapy in GH-secreting adenomas, and to
compare the results concerning control of disease with previous series using
older criteria of cure. Method: We report on a consecutive series of 688
acromegalic patients treated over a time period of 19 years. Biochemical cure
was defined as n... hiện toàn bộ
The 2021 European Group on Graves’ orbitopathy (EUGOGO) clinical practice guidelines for the medical management of Graves’ orbitopathy Tập 185 Số 4 - Trang G43-G67 - 2021
Luigi Bartalena, George J. Kahaly, Kostas Boboridis, Colin Dayan, Anja Eckstein, C Marcocci, Michele Marinò, Bijay Vaidya, Wilmar M. Wiersinga, _ _, Göksün Ayvaz, Onur Konuk, Jasmina Ćirić, Biljana Beleslin, Antonella Boschi, Maria Cristina Burlacu, Diane H. Morris, Rosario Le Moli, Antonio Marino, Justin McKee, Nicole Zammit, Dagmar Führer, Ioana Pereni, Michael Schittkowski, Dirk Raddatz, Vickie Lee, Karim Meeran, Juliette Abeillon, Thia Soui Thcong, Katharina A. Ponto, Ilaria Muller, Nicola Currò, Christoph Hintschich, Roland Gärtner, Simon H. S. Pearce, Lucy Clarke, Thomas Heiberg Brix, Dorte Bechtold, Gottfried Rudovfsky, N. Fichter, L. Pasquier, J. Meney, Francesca Menconi, Giulia Lanzolla, Gangadhara Sundar, Susan Yung, Panagiotis Anagnostis, Ma Mercedes Cuevas López, Carlos Javier Frías Sánchez, Maria Laura Tanda, Simone Donati, Andrea Papp, Shuren Li, Anna Jabłońska, Piotr Miśkiewicz, Jelena Juri, Maja Baretić
Graves’ orbitopathy (GO) is the main extrathyroidal manifestation of Graves’
disease (GD). Choice of treatment should be based on the assessment of clinical
activity and severity of GO. Early referral to specialized centers is
fundamental for most patients with GO. Risk factors include smoking, thyroid
dysfunction, high serum level of thyrotropin receptor antibodies, radioactive
iodine (RAI) treat... hiện toàn bộ
AME Position Statement on adrenal incidentaloma Tập 164 Số 6 - Trang 851-870 - 2011
Massimo Terzolo, Antonio Stigliano, Iacopo Chiodini, Paola Loli, Lino Furlani, Giorgio Arnaldi, Giuseppe Reimondo, Anna Pia, Vincenzo Toscano, Michele Zini, Giorgio Borretta, Enrico Papini, Piernicola Garofalo, Bruno Allolio, B. Dupas, Franco Mantero, Antoine Tabarin
ObjectiveTo assess currently available evidence on adrenal incidentaloma and
provide recommendations for clinical practice.DesignA panel of experts
(appointed by the Italian Association of Clinical Endocrinologists (AME))
appraised the methodological quality of the relevant studies, summarized their
results, and discussed the evidence reports to find consensus.Radiological
assessmentUnenhanced com... hiện toàn bộ
Body mass index, circulating levels of sex-steroid hormones, IGF-I and IGF-binding protein-3: a cross-sectional study in healthy women - Trang 161-171 - 2004
Anne Zeleniuch‐Jacquotte, Eva Lundin, Paola Muti, Anthony J. Mure, Sabina Rinaldi, Laure Dossus, Andrea Micheli, Alan A. Arslan, Per Lenner, Roy E. Shore, Vittorio Krogh, KL Koenig, Elio Ríboli, Franco Berrino, G. Hallmans, Kim Overvad, Paolo Toniolo, Sabina Sieri
OBJECTIVE: Excess weight has been associated with increased risk of cancer at
several organ sites. In part, this effect may be modulated through alterations
in the metabolism of sex steroids and IGF-I related peptides. The objectives of
the study were to examine the association of body mass index (BMI) with
circulating androgens (testosterone, androstenedione and dehydroepiandrosterone
sulfate (DH... hiện toàn bộ