Glucagon‐like peptide‐1 cells in the gastrointestinal tract and pancreas of rat, pig and man Tập 22 Số 4 - Trang 283-291 - 1992
R Eissele, R Göke, S Willemer, H P Harthus, Hans J. Vermeer, Rudolf Arnold, Burkhard Göke
Abstract. A highly specific monoclonal antibody directed against the C‐terminal part of glucagon‐like peptide‐1 (GLP‐1) was raised to immunohistochemi‐cally evaluate the distribution of GLP‐1 containing cells in the entire gastrointestinal tract including pancreas of rat, pig and man. In the pancreas GLP‐1 ‐immunoreactive cells were found variously shaped and predom...... hiện toàn bộ Radioimmunoassay for type III procollagen peptide and its application to human liver disease Tập 9 Số 6 - Trang 451-459 - 1979
Heilwig Rohde, L. Vargas, ECKHARTHAHN, H Kalbfleisch, Miguel Bruguera, Rupert Timpl
Abstract. A sensitive and specific radioimmunoassay was developed for the precursor‐specific peptide segment located at the amino end of bovine type III procollagen. Human material showed high cross‐reactivity in this assay. Two forms of human procollagen peptides were detected in body fluids. The larger peptide (45K) was found in serum and ascites, and resembled th...... hiện toàn bộ STrengthening the REporting of Genetic Association studies (STREGA) – an extension of the STROBE statement Tập 39 Số 4 - Trang 247-266 - 2009
Julian Little, Julian P. T. Higgins, John P. A. Ioannidis, David Moher, France Gagnon, Erik von Elm, Muin J. Khoury, Barbara Cohen, George Davey Smith, Jeremy Grimshaw, Paul Scheet, Marta Gwinn, Robin E. Williamson, Guangyong Zou, Kim Hutchings, Candice Y. Johnson, Valerie Tait, Miriam Wiens, Jean Golding, Cornelia M. van Duijn, John McLaughlin, Andrew D. Paterson, George A. Wells, Isabel Fortier, Matthew L. Freedman, Maja Zečević, Richard King, Claire Infante‐Rivard, Alexandre F.R. Stewart, Nick Birkett
AbstractMaking sense of rapidly evolving evidence on genetic associations is crucial to making genuine advances in human genomics and the eventual integration of this information in the practice of medicine and public health. Assessment of the strengths and weaknesses of this evidence, and hence the ability to synthesize it, has been limited by inadequate reporting...... hiện toàn bộ Localization of collagen mRNA in normal and scleroderma skin by in‐situ hybridization Tập 18 Số 1 - Trang 9-17 - 1988
Karin Scharffetter, Brigitte Lankat‐Buttgereit, Thomas Krieg
Abstract. Scleroderma is a fibrotic disease occurring in a localized or systemic form. Disturbed regulation of connective tissue metabolism plays an important role in its pathogenesis. However, until now, most of the data available were obtained from studies of fibroblasts in culture and there is considerable doubt that fibroblasts in a monolayer reflect the ... hiện toàn bộ