Epileptic Disorders
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EEG features of nonconvulsive status epilepticus
Epileptic Disorders - Tập 14 - Trang 442-445 - 2013
Nonconvulsive status epilepticus (NCSE) is diagnosed in practice as an enduring epileptic condition with reduced or altered consciousness, but without major convulsive movements, and epileptiform discharges on EEG. In this article, an illustrative and paradigmatic case is presented with a focus on the main EEG features which should be considered when there is clinical suspicion of NCSE. Some clini......
Focal epileptic seizure induced by transient hypoglycaemia in insulin-treated diabetes
Epileptic Disorders - Tập 12 - Trang 84-87 - 2010
Hypoglycaemia, common in diabetic patients treated with insulin, can induce various neurological disturbances. Of these, seizures are the most common acute symptom, mainly of the generalised tonic-clonic type, with focal events only exceptionally being reported and documented. Hypoglycaemia can modify cortical excitability by determining an imbalance between excitation and inhibition; some brain s......
Late-onset Rasmussen’s encephalitis and long-term remission
Epileptic Disorders - Tập 13 - Trang 88-91 - 2011
We describe an adult man with biopsy-proven Rasmussen’s encephalitis and intractable epilepsy, who underwent excellent recovery. To our knowledge, this is the first report of a patient with Rasmussen’s encephalitis who has become completely symptomless, at least for three years, on enhanced antiepileptic and immunological medication.
Mirth and laughter elicited during brain stimulation
Epileptic Disorders - Tập 13 - Trang 435-440 - 2012
There are few reports of laughter and/or mirth evoked by electrical stimulation of the brain. In this study, we present a patient with intractable epilepsy in whom mirth and laughter was consistently produced during stimulation of the left inferior frontal gyrus (opercular part) using stereotactically placed depth electrodes. A review of the literature shows that cortical sites that produce mirth ......
A common reference-based indirect comparison meta-analysis of intravenous valproate versus intravenous phenobarbitone for convulsive status epilepticus
Epileptic Disorders - Tập 15 - Trang 314-323 - 2013
To compare intravenous valproate (IV-VPA) with intravenous phenobarbitone (IV-PB) in the treatment of established generalised convulsive status epilepticus (GCSE). Efficacy and safety were estimated using a common-reference based indirect comparison metaanalysis (CRBMA) methodology. Randomised controlled trials (RCTs) investigating the use of IV-VPA or IV-PB versus intravenous phenytoin (IV-PHT) f......
Novel familial cases of ICCA (infantile convulsions with paroxysmal choreoathetosis) syndrome
Epileptic Disorders - Tập 12 - Trang 199-204 - 2010
Epilepsy and paroxysmal dyskinesia are two episodic cerebral disorders that can share a common genetic basis. Rare families with infantile seizures and paroxysmal dyskinesia [predominantly paroxysmal kinesigenic dyskinesia (PKD)], co-inherited as a single autosomal dominant trait, have been described (infantile convulsions with paroxysmal choreoathetosis; ICCA syndrome) and a disease gene has been......
Video/EEG findings in a KCNQ2 epileptic encephalopathy: a case report and revision of literature data
Epileptic Disorders - Tập 15 - Trang 158-165 - 2013
We describe the EEG findings of an infant with early-onset epileptic encephalopathy with mutation of the KCNQ2 gene and a family history of neonatal seizures. The infant presented with multifocal drugresistant seizures with onset during the third day of life. Family history was positive for early-onset neonatal seizures. Metabolic screening and neuroimaging were negative. Direct sequencing of KCQN......
Type I focal cortical dysplasia: surgical outcome is related to histopathology
Epileptic Disorders - Tập 12 - Trang 181-191 - 2010
Pre-surgical and post-surgical data were examined and compared from 215 consecutive patients undergoing surgery for intractable epilepsy. Patients were selected on the basis of a proven histopathological diagnosis of type I focal cortical dysplasia (FCD I), alone or associated with other lesions. The patients were divided into five sub-groups: i) 66 with isolated FCD I, ii) 76 with FCD I and hippo......
Management and monitoring of patients treated with zonisamide: the OZONE studyABSTRACT Aim Tocharacterise patients treated with zonisamide in everyday practice and describe the effectiveness and tolerability of treatment. Methods This was an observational, longitudinal, naturalistic study, conducted by neurologists in France. Patients who had starte...
Epileptic Disorders - - 2013
Episodes of loss of consciousness in a patient with a background of cerebral venous thrombosis
Epileptic Disorders - Tập 15 - Trang 175-180 - 2013
Episodes of loss of consciousness are common, even in young, healthy people, and can sometimes represent a diagnostic challenge. The main diagnoses to consider are syncope and epileptic seizures, both of which may have similar symptomatology such as dizziness, loss of consciousness, falls, or “convulsive” phenomena. We present the case of a young male patient with a background of two venous thromb......
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