Epileptic Disorders
Công bố khoa học tiêu biểu
* Dữ liệu chỉ mang tính chất tham khảo
Sắp xếp:
Focal epileptic seizure induced by transient hypoglycaemia in insulin-treated diabetes
Epileptic Disorders - Tập 12 - Trang 84-87 - 2010
Hypoglycaemia, common in diabetic patients treated with insulin, can induce various neurological disturbances. Of these, seizures are the most common acute symptom, mainly of the generalised tonic-clonic type, with focal events only exceptionally being reported and documented. Hypoglycaemia can modify cortical excitability by determining an imbalance between excitation and inhibition; some brain s......
Late-onset Rasmussen’s encephalitis and long-term remission
Epileptic Disorders - Tập 13 - Trang 88-91 - 2011
We describe an adult man with biopsy-proven Rasmussen’s encephalitis and intractable epilepsy, who underwent excellent recovery. To our knowledge, this is the first report of a patient with Rasmussen’s encephalitis who has become completely symptomless, at least for three years, on enhanced antiepileptic and immunological medication.
A common reference-based indirect comparison meta-analysis of intravenous valproate versus intravenous phenobarbitone for convulsive status epilepticus
Epileptic Disorders - Tập 15 - Trang 314-323 - 2013
To compare intravenous valproate (IV-VPA) with intravenous phenobarbitone (IV-PB) in the treatment of established generalised convulsive status epilepticus (GCSE). Efficacy and safety were estimated using a common-reference based indirect comparison metaanalysis (CRBMA) methodology. Randomised controlled trials (RCTs) investigating the use of IV-VPA or IV-PB versus intravenous phenytoin (IV-PHT) f......
Novel familial cases of ICCA (infantile convulsions with paroxysmal choreoathetosis) syndrome
Epileptic Disorders - Tập 12 - Trang 199-204 - 2010
Epilepsy and paroxysmal dyskinesia are two episodic cerebral disorders that can share a common genetic basis. Rare families with infantile seizures and paroxysmal dyskinesia [predominantly paroxysmal kinesigenic dyskinesia (PKD)], co-inherited as a single autosomal dominant trait, have been described (infantile convulsions with paroxysmal choreoathetosis; ICCA syndrome) and a disease gene has been......
Video/EEG findings in a KCNQ2 epileptic encephalopathy: a case report and revision of literature data
Epileptic Disorders - Tập 15 - Trang 158-165 - 2013
We describe the EEG findings of an infant with early-onset epileptic encephalopathy with mutation of the KCNQ2 gene and a family history of neonatal seizures. The infant presented with multifocal drugresistant seizures with onset during the third day of life. Family history was positive for early-onset neonatal seizures. Metabolic screening and neuroimaging were negative. Direct sequencing of KCQN......
Management and monitoring of patients treated with zonisamide: the OZONE studyABSTRACT Aim Tocharacterise patients treated with zonisamide in everyday practice and describe the effectiveness and tolerability of treatment. Methods This was an observational, longitudinal, naturalistic study, conducted by neurologists in France. Patients who had starte...
Epileptic Disorders - - 2013
Episodes of loss of consciousness in a patient with a background of cerebral venous thrombosis
Epileptic Disorders - Tập 15 - Trang 175-180 - 2013
Episodes of loss of consciousness are common, even in young, healthy people, and can sometimes represent a diagnostic challenge. The main diagnoses to consider are syncope and epileptic seizures, both of which may have similar symptomatology such as dizziness, loss of consciousness, falls, or “convulsive” phenomena. We present the case of a young male patient with a background of two venous thromb......
Fronto-polar epilepsy masquerading as juvenile myoclonic epilepsy
Epileptic Disorders - Tập 13 - Trang 317-320 - 2012
A woman diagnosed with juvenile myoclonic epilepsy for over 30 years presented with stereotyped episodes of abnormal sensations in both arms. Continuous video-EEG monitoring for 14 days and MRI brain revealed that the patient’s somatosensory events with associated postictal aphasia, as well as her myoclonic and generalised tonic-clonic seizures, were likelydueto a symptomatic left fronto-polar epi......
Gastaut type idiopathic childhood occipital epilepsy
Epileptic Disorders - Tập 15 - Trang 80-83 - 2013
Gastaut type idiopathic childhood occipital epilepsy is an uncommon epileptic syndrome characterised by frequent seizures, most commonly presenting as elementary visual hallucinations or blindness. Other occipital (non-visual) symptoms may also occur. Interictal EEG typically shows occipital paroxysms, often with fixation-off sensitivity. Ictal EEG is usually characterised by interruption by parox......
The evolution of antiepileptic drug development and regulation
Epileptic Disorders - Tập 12 - Trang 3-15 - 2010
The early years of antiepileptic drug development were characterised by observation and serendipity, rather than a rational, targeted approach to drug development. Control of seizures was seen as the primary aim of therapy, with much less focus on safety and tolerability. However, experience with thalidomide in the 1960s brought safety to the fore, resulting in an era of much tighter regulatory co......
Tổng số: 187
- 1
- 2
- 3
- 4
- 5
- 6
- 10