Epilepsia Open

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Efficacy of long‐term adrenocorticotropic hormone therapy for West syndrome: A retrospective multicenter case series
Epilepsia Open - Tập 6 Số 2 - Trang 402-412 - 2021
Shimpei Baba, Tohru Okanishi, Yoichiro Homma, Takeshi Yoshida, Tomohide Goto, Toshio Fukasawa, Satoru Kobayashi, Atsushi Kamei, Yuji Fujii, Naomi Hino‐Fukuyo, Keitaro Yamada, Atsuro Daida, Hisashi Kawawaki, Hideki Hoshino, Hitoshi Sejima, Yusuke Ishida, Tetsuya Okazaki, Takehiko Inui, Sotaro Kanai, Hirotaka Motoi, Shinji Itamura, Mitsuyo Nishimura, Hideo Enoki, Ayataka Fujimoto
AbstractObjectivesLong‐term adrenocorticotropic therapy (LT‐ACTH), which consisted of 2‐4 weeks of daily injections of adrenocorticotropic hormone (ACTH) and subsequent months of weekly injections, was tried for relapsed West syndrome (WS) or other intractable epilepsies in small case reports. Our aim was to explore the efficacy o...... hiện toàn bộ
Glut1 Deficiency Syndrome (Glut1DS): State of the art in 2020 and recommendations of the international Glut1DS study group
Epilepsia Open - Tập 5 Số 3 - Trang 354-365 - 2020
Joerg Klepper, Cigdem I. Akman, Marisa Armeno, Stéphane Auvin, Mackenzie C. Cervenka, J. Helen Cross, Valentina De Giorgis, Adela Della Marina, Kristin Engelstad, Nicole Heußinger, Eric H. Kossoff, Wilhelmina G. Leen, B. Leiendecker, Umrao R. Monani, Hirokazu Oguni, Elizabeth Neal, Juan M. Pascual, Toni S. Pearson, Roser Pons, Ingrid E. Scheffer, Pierangelo Veggiotti, Michèl A.A.P. Willemsen, Sameer M. Zuberi, Darryl C. De Vivo
AbstractGlut1 deficiency syndrome (Glut1DS) is a brain energy failure syndrome caused by impaired glucose transport across brain tissue barriers. Glucose diffusion across tissue barriers is facilitated by a family of proteins including glucose transporter type 1 (Glut1). Patients are treated effectively with ketogenic diet therapies (KDT) that provide a supplementa...... hiện toàn bộ
Optimal clinical management of children receiving dietary therapies for epilepsy: Updated recommendations of the International Ketogenic Diet Study Group
Epilepsia Open - Tập 3 Số 2 - Trang 175-192 - 2018
Eric H. Kossoff, Beth Zupec‐Kania, Stéphane Auvin, Karen Ballaban‐Gil, Anna Bergqvist, Robyn Blackford, Jeffrey Buchhalter, Roberto Caraballo, J. Helen Cross, Maria Dahlin, Elizabeth Donner, Orkide Güzel, Rana Jehle, Joerg Klepper, Hoon‐Chul Kang, Danielle A.J.E. Lambrechts, Y.M. Christiana Liu, Janak Nathan, Douglas R. Nordli, Heidi H. Pfeifer, Jong M. Rho, Ingrid E. Scheffer, Suvasini Sharma, Carl E. Stafstrom, Elizabeth A. Thiele, Zahava Turner, María Magdalena Vaccarezza, Elles J.T.M. van der Louw, Pierangelo Veggiotti, James W. Wheless, Elaine Wirrell
SummaryKetogenic dietary therapies (KDTs) are established, effective nonpharmacologic treatments for intractable childhood epilepsy. For many yearsKDTswere implemented differently throughout the world due to lack of consistent protocols. In 20...... hiện toàn bộ
Incidence of potential adverse events during hospital‐based ketogenic diet initiation among children with drug‐resistant epilepsy
Epilepsia Open - Tập 5 Số 4 - Trang 596-604 - 2020
Ali Mir, MahmoodDhahir Al-Mendalawi, Abdullah Alamri, Mohammed Al-Qahtani, Entisar Hany, Aqeel Hussain, Michael Joseph, Shahid Bashir
AbstractObjectiveDue to the possibility of serious adverse events (AE), patients are commonly admitted to hospital for 3‐5 days for ketogenic diet (KD) initiation. This study examined the incidence of potential AE during admission for KD initiation to investigate the possibility of safely initiating a KD at home.... hiện toàn bộ
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