Endocrine Pathology

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Hypothalamic neurocytoma with vasopressin immunoreactivity: Immunohistochemical and ultrastructural observations
Endocrine Pathology - Tập 3 - Trang 99-104 - 1992
John A. Maguire, Juan M. Bilbao, Kaiman Kovacs, Lothar Resch
Hypothalamic tumors of neuronal derivation are rare. We describe the case of a 55-year-old woman with visual disturbances who was found by magnetic resonance imaging (MRI) to have a sellar and suprasellar tumor. She underwent subtotal surgical resection by a transsphe-noidal approach. By light microscopy the tumor displayed a uniform population of short spindle cells with round to oval nuclei, sep...... hiện toàn bộ
A Matched-Pair Analysis of Nuclear Morphologic Features Between Core Needle Biopsy and Surgical Specimen in Thyroid Tumors Using a Deep Learning Model
Endocrine Pathology - Tập 33 - Trang 472-483 - 2022
Faridul Haq, Andrey Bychkov, Chan Kwon Jung
Core needle biopsy (CNB) is a method that can be used as an alternative to fine-needle aspiration for the sampling of thyroid nodules to provide a preoperative diagnosis. Nuclear atypia is of paramount importance in diagnosing thyroid tumors. We aimed to identify the differences in nuclear morphologic features between CNB and surgical specimens. Quantitative image analysis was performed on whole s...... hiện toàn bộ
Biểu hiện mRNA insulin và glucagon cũng như phản ứng miễn dịch của prohormone convertase trong mô nội tiết tụy bình thường và u Dịch bởi AI
Endocrine Pathology - Tập 11 - Trang 179-183 - 2000
Mark Rodacker, Long Jin, Shuga Zhang, Ricardo V. Lloyd
Prohormone convertase (PC) 1/3 và PC2 là các enzym đặc hiệu cho hệ thần kinh nội tiết, chuyển đổi các prohormone thành hormone hoạt động. Để tìm hiểu thêm về vai trò của các PC này trong các tế bào tiểu đảo bình thường và u bướu, chúng tôi đã phân tích một loạt các khối u nội tiết tụy nhằm xác định vai trò của PC1/3 và PC2 trong quá trình xử lý hormone của tế bào tiểu đảo. Kỹ thuật lai tại chỗ với...... hiện toàn bộ
#prohormone convertase #PC1/3 #PC2 #insulin #glucagon #u nội tiết tụy #tiểu đảo tụy
Spindle epithelial tumor with thymus-like differentiation (SETTLE) of the thyroid with neck lymph node metastasis: A case report
Endocrine Pathology - Tập 16 - Trang 139-143 - 2005
Aleksandr Yu. Abrosimov, Virginia A. LiVolsi
Spindle epithelial tumor with thymus-like differentiation (SETTLE) is an extremely rare type of thyroid tumor. It has been reported only 20 times in the English literature. This tumor occurs predominantly in young patients and has a protracted clinical course despite the occurrence of metastases. In the recent literature SETTLE has been considered to be a tumor of low malignant potential with dist...... hiện toàn bộ
Histologic, immunohistochemical, and ultrastructural findings in a case of minocycline-associated “black thyroid”
Endocrine Pathology - Tập 12 - Trang 443-451 - 2001
C. David Bell, Kalman Kovacs, Eva Horvath, Fabio Rotondo
We report on a 37-yr-old woman with known antemortem ingestion of minocyclin who died suddenly from a ruptured cerebral aneurysm. At autopsy, her thyroid gland, although not enlarged, was diffusely black, caused by the deposition of a melanin-like pigment that stained positive with Schmorl’s reagent. The pigment could be bleached with permanganate, and on examination by electron microscopy, it app...... hiện toàn bộ
Complex Endocrinopathies in MEN-1: Diagnostic Dilemmas in Endocrine Oncology
Endocrine Pathology - Tập 18 - Trang 37-41 - 2007
Nabeel Y. Y. Al Brahim, Gloria Rambaldini, Shereen Ezzat, Sylvia L. Asa
Endocrine oncology is a complex area that must determine the site of a neoplastic process and the hormonal dysregulation that ensues. Patients with endocrine tumors often have delayed diagnosis because of the nonspecific and often subtle signs and symptoms. In patients with multiple endocrine neoplasia syndromes, diagnosis and clinicopathologic correlations can be even more challenging. We report ...... hiện toàn bộ
Recent advances in histopathology and immunohistochemistry of adrenocortical carcinoma
Endocrine Pathology - Tập 17 - Trang 345-354 - 2006
Hironobu Sasano, Takashi Suzuki, Takuya Moriya
Discerning malignancy in resected adrenocortical neoplasms can pose diagnostic difficulty. Macroscopic examination is the first important step toward diagnosis and should include accurate measurement of weight and dimension of the specimens and description of the cut surface of the tumors. It is also important to sample the specimens for histological diagnosis near foci of hemorrhage and/or necros...... hiện toàn bộ
Fat-cell metaplasia in the adrenal cortex: Incidence, structure, and correlation to basic diseases in a postmortem series
Endocrine Pathology - Tập 9 - Trang 241-247 - 1998
Wolfgang Saeger, Karin Reinhard
In a postmortem series of adrenals from 497 patients 25 cases (5%) showed foci of fat-cell metaplasia or bone-marrow metaplasia in the zona fasciculata or the zona reticularis. There was only one focus in 4.5% of adrenals with metaplasia, but in 36.4%, more than six foci were present. The sizes varied between 0.036 and 0.64 mm. The foci were composed of mature, mostly univacuolar, fat cells and va...... hiện toàn bộ
Definition of Poorly Differentiated Carcinoma of the Thyroid: The Japanese Experience
Endocrine Pathology - Tập 15 Số 4 - Trang 307-312
Atsuhiko Sakamoto
Follicular Thyroid Carcinoma Presenting as a Massive Chest Wall Tumor
Endocrine Pathology - Tập 24 - Trang 20-24 - 2012
Ryan Gertz, Rakesh Sarda, Ricardo Lloyd
The initial presentation of follicular thyroid carcinoma is rarely related to metastatic lesions. Presented here is the case of a 70-year-old woman with the initial presentation of a 13-cm chest wall mass identified as a metastatic follicular thyroid carcinoma. The chest wall lesion had features of a poorly differentiated carcinoma with areas of necrosis, an insular growth pattern focally and incr...... hiện toàn bộ
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