RIG‐I antiviral signaling drives interleukin‐23 production and psoriasis‐like skin diseaseEMBO Molecular Medicine - Tập 9 Số 5 - Trang 589-604 - 2017
Huanhuan Zhu, Fangzhou Lou, Qianqian Yin, Yuanyuan Gao, Yang Sun, Jing Bai, Zhenyao Xu, Zhaoyuan Liu, Wei Cai, Ke Fang, Yukui Zhang, Hong Zhou, Hong Wang, Gang Wang, Xiang Chen, Hongxin Zhang, Zhugang Wang, Florent Ginhoux, Chuanjian Lu, Bing Su, Honglin Wang
Activation of rapid oestrogen signalling in aggressive human breast cancersEMBO Molecular Medicine - Tập 4 Số 11 - Trang 1200-1213 - 2012
Coralie Poulard, Isabelle Treilleux, Emilie Lavergne, Katia Bouchekioua‐Bouzaghou, Sophie Goddard‐Léon, Sylvie Chabaud, Olivier Trédan, Laura Corbo, Muriel Le Romancer
AbstractOestrogen receptors can mediate rapid activation of cytoplasmic signalling cascades by recruiting Src and PI3K. However, the involvement of this pathway in breast cancer remains poorly defined. We have previously shown that methylation of ERα is required for the formation of the ERα/Src/PI3K complex and that ERα is hypermethylated in a subset of breast canc...... hiện toàn bộ
The 28‐amino acid form of an APLP1‐derived Aβ‐like peptide is a surrogate marker for Aβ42 production in the central nervous systemEMBO Molecular Medicine - Tập 1 Số 4 - Trang 223-235 - 2009
Kanta Yanagida, Masayasu Okochi, Shinji Tagami, Taisuke Nakayama, Takashi Kodama, Kouhei Nishitomi, Jingwei Jiang, Kohji Mori, Shinichi Tatsumi, Tetsuaki Arai, Takeshi Ikeuchi, Kensaku Kasuga, Takahiko Tokuda, Masaki Kondo, Masaki Ikeda, Kentaro Deguchi, Hiroaki Kazui, Toshihisa Tanaka, Takashi Morihara, Ryota Hashimoto, Takashi Kudo, Harald Steiner, Christian Haass, Kuniaki Tsuchiya, Haruhiko Akiyama, Ryozo Kuwano, Masatoshi Takeda
Low‐dose TNF augments fracture healing in normal and osteoporotic bone by up‐regulating the innate immune responseEMBO Molecular Medicine - Tập 7 Số 5 - Trang 547-561 - 2015
James Chan, Graeme E. Glass, Adel Ersek, Andrew Freidin, Graham V. Williams, Kate H.C. Gowers, Ana Isabel Espirito Santo, Rosemary Jeffery, W Otto, Richard Poulsom, Marc Feldmann, Sara M. Rankin, Nicole J. Horwood, Jagdeep Nanchahal
AbstractThe mechanism by which trauma initiates healing remains unclear. Precise understanding of these events may define interventions for accelerating healing that could be translated to the clinical arena. We previously reported that addition of low‐dose recombinant human TNF (rh... hiện toàn bộ
Functional systemic CD 4 immunity is required for clinical responses to PD ‐L1/ PD ‐1 blockade therapyEMBO Molecular Medicine - Tập 11 Số 7 - 2019
Miren Zuazo, Hugo Arasanz, G. Fernández-Hinojal, María Jesús García-Granda, María Gato, Ana Bocanegra, M. Rico, Berta Hernández, Lucía Teijeira, Idoia Morilla, María José Lecumberri, Ángela Fernández de Lascoiti, Ruth Vera, Grazyna Kochan, David Escors
Sequential treatment with 5‐aza‐2′‐deoxycytidine and deacetylase inhibitors reactivates HIV‐1EMBO Molecular Medicine - Tập 8 Số 2 - Trang 117-138 - 2016
Sophie Bouchat, Nadège Delacourt, Anna Kula, Gilles Darcis, Benoît Van Driessche, Francis Corazza, Jean‐Stéphane Gatot, Adeline Mélard, Caroline Vanhulle, Kabamba Kabeya, Marion Pardons, Véronique Avettand-Fènoël, Nathan Clumeck, Stéphane De Wit, Olivier Rohr, Christine Katlama, Carine Van Lint
AbstractReactivation of HIV gene expression in latently infected cells together with an efficient cART has been proposed as an adjuvant therapy aimed at eliminating/decreasing the reservoir size. Results from hiện toàn bộ