EJNMMI Physics

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Accelerated SPECT image reconstruction with FBP and an image enhancement convolutional neural network
EJNMMI Physics - Tập 6 Số 1 - Trang 1-12 - 2019
Dietze, Martijn M. A., Branderhorst, Woutjan, Kunnen, Britt, Viergever, Max A., de Jong, Hugo W. A. M.
Monte Carlo-based iterative reconstruction to correct for photon scatter and collimator effects has been proven to be superior over analytical correction schemes in single-photon emission computed tomography (SPECT/CT), but it is currently not commonly used in daily clinical practice due to the long associated reconstruction times. We propose to use a convolutional neural network (CNN) to upgrade ...... hiện toàn bộ
The dynamics of physics in PET
EJNMMI Physics - Tập 1 - Trang 1-4 - 2014
Charles C Watson
From a technical perspective, there are fundamentally two forces driving the evolution of instrumentation in positron emission tomography (PET) and nuclear medicine generally: clinical needs and technical innovation. This essay considers some of the dynamics of these forces as they act on physics-related developments in PET and suggests that progress will be greatest if these differing motivations...... hiện toàn bộ
Algorithms for joint activity–attenuation estimation from positron emission tomography scatter
EJNMMI Physics - Tập 6 - Trang 1-30 - 2019
Yannick Berker, Volkmar Schulz, Joel S. Karp
Attenuation correction in positron emission tomography remains challenging in the absence of measured transmission data. Scattered emission data may contribute missing information, but quantitative scatter-to-attenuation (S2A) reconstruction needs to input the reconstructed activity image. Here, we study S2A reconstruction as a building block for joint estimation of activity and attenuation. We st...... hiện toàn bộ
Accuracy of 177Lu activity quantification in SPECT imaging: a phantom study
EJNMMI Physics - Tập 4 - Trang 1-20 - 2017
Carlos F. Uribe, Pedro L. Esquinas, Jesse Tanguay, Marjorie Gonzalez, Emilie Gaudin, Jean-Mathieu Beauregard, Anna Celler
The aim of the study is to assess accuracy of activity quantification of 177Lu studies performed according to recommendations provided by the committee on Medical Internal Radiation Dose (MIRD) pamphlets 23 and 26. The performances of two scatter correction and three segmentation methods were compared. Additionally, the accuracy of tomographic and planar methods for determination of the camera nor...... hiện toàn bộ
Minimization of border effects in monolithic scintillators using neural networks, based on MR-compatible SiPM arrays
EJNMMI Physics - Tập 1 - Trang 1-2 - 2014
Pablo Conde, Amadeo Iborra, Antonio J González, Liczandro Hernández, Pablo Bellido, Efrén Crespo, Laura Moliner, Juan P Rigla, María J Rodríguez-Álvarez, Filomeno Sánchez, Michael Seimetz, Antonio Soriano, Luis Fernando Vidal, José M Benlloch
Understanding the importance of quality control and quality assurance in preclinical PET/CT imaging
EJNMMI Physics - Tập 9 Số 1
Wendy McDougald, Julia G. Mannheim
AbstractThe fundamental principle of experimental design is to ensure efficiency and efficacy of the performed experiments. Therefore, it behoves the researcher to gain knowledge of the technological equipment to be used. This should include an understanding of the instrument quality control and assurance requirements to avoid inadequate or spurious results due to ...... hiện toàn bộ
Method to determine the statistical technical variability of SUV metrics
EJNMMI Physics - Tập 9 - Trang 1-16 - 2022
Giulia M. R. De Luca, Jan B. A. Habraken
The Standardized Uptake Value (SUV) Max, SUVMean, and SUVPeak are metrics used to quantify positron emission tomography (PET) images. In order to assess the significance of a change in these metrics for diagnostic purposes, it is relevant to know their variation. The sources of variation can be biological or technical. In this study, we present a method to determine the statistical technical varia...... hiện toàn bộ
An automatic pipeline for PET/MRI attenuation correction validation in the brain
EJNMMI Physics - Tập 10 Số 1
Mahdjoub Hamdi, Chunwei Ying, Hongyu An, Richard Laforest
Abstract Purpose Challenges in PET/MRI quantitative accuracy for neurological uses arise from PET attenuation correction accuracy. We proposed and evaluated an automatic pipeline to assess the quantitative accuracy of four MRI-derived PET AC methods using analytically simulated PET brain lesions and...... hiện toàn bộ
Radiation doses from 161Tb and 177Lu in single tumour cells and micrometastases
EJNMMI Physics - Tập 7 - Trang 1-9 - 2020
Mario E. Alcocer-Ávila, Aymeric Ferreira, Michele A. Quinto, Clément Morgat, Elif Hindié, Christophe Champion
Targeted radionuclide therapy (TRT) is gaining importance. For TRT to be also used as adjuvant therapy or for treating minimal residual disease, there is a need to increase the radiation dose to small tumours. The aim of this in silico study was to compare the performances of 161Tb (a medium-energy β− emitter with additional Auger and conversion electron emissions) and 177Lu for irradiating single...... hiện toàn bộ
Development and evaluation of an automated quantification tool for amyloid PET images
EJNMMI Physics - Tập 7 Số 1 - 2020
Yuma Tsubaki, Go Akamatsu, Natsumi Shimokawa, Suguru Katsube, Aya Takashima, Masayuki Sasaki, Japanese Alzheimer’s Disease Neuroimaging Initiative
Abstract Background Quantitative evaluation of amyloid positron emission tomography (PET) with standardized uptake value ratio (SUVR) plays a key role in clinical studies of Alzheimer’s disease (AD). We have proposed a PET-only (MR-free) amyloid quantification method, although some commercial software packages are required. The ai...... hiện toàn bộ
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