EJNMMI Physics

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Image quality assessment along the one metre axial field-of-view of the total-body Biograph Vision Quadra PET/CT system for 18F-FDG
EJNMMI Physics - Tập 9 - Trang 1-17 - 2022
Ivo Rausch, Julia G. Mannheim, Jürgen Kupferschläger, Christian la Fougère, Fabian P. Schmidt
Recently, total-body PET/CT systems with an extended axial field-of-view (aFOV) became commercially available which allow acquiring physiologic information of multiple organs simultaneously. However, the nominal aFOV may clinically not be used effectively due to the inherently reduced sensitivity at the distal ends of the aFOV. The aim of this study was to assess the extent of the useful aFOV of t...... hiện toàn bộ
Distortion correction of MR data in whole-body small animal PET-MR using 3D thin-plate splines
EJNMMI Physics - Tập 1 - Trang 1-2 - 2014
Lynn Frohwein, Verena Hoerr, Cornelius Faber, Klaus Schäfers
Evaluation of the performance of a high-resolution time-of-flight PET system dedicated to the head and breast according to NEMA NU 2-2012 standard
EJNMMI Physics - Tập 9 Số 1
Daisuke Morimoto‐Ishikawa, Kohei Hanaoka, Shota Watanabe, Takahiro Yamada, Yoshiyuki Yamakawa, Suzuka Minagawa, Shiho Takenouchi, A. Ohtani, Tetsuro Mizuta, Hayato Kaida, Kazunari Ishii
Abstract Background This study evaluated the physical performance of a positron emission tomography (PET) system dedicated to the head and breast according to the National Electrical Manufacturers Association (NEMA) NU2-2012 standard. ... hiện toàn bộ
Feasibility of PET/CT system performance harmonisation for quantitative multicentre 89Zr studies
EJNMMI Physics - Tập 5 - Trang 1-8 - 2018
Andres Kaalep, Marc Huisman, Terez Sera, Danielle Vugts, Ronald Boellaard
The aim of this study was to investigate the variability in quantitative performance and feasibility of quantitative harmonisation in 89Zr PET/CT imaging. Eight EANM EARL-accredited (Kaalep A et al., Eur J Nucl Med Mol Imaging 45:412–22, 2018) PET/CT systems were investigated using phantom acquisitions of uniform and NEMA NU2-2007 body phantoms. The phantoms were filled according to EANM EARL guid...... hiện toàn bộ
Human biodistribution and dosimetry of [11C]-UCB-J, a PET radiotracer for imaging synaptic density
EJNMMI Physics - - 2021
Christopher Cawthorne, Paul Maguire, Joel Mercier, David Sciberras, Kim Serdons, Guy Bormans, Jan de Hoon, Koen Van Laere, Michel Koole
[11C]-UCB-J is an emerging tool for the noninvasive measurement of synaptic vesicle density in vivo. Here, we report human biodistribution and dosimetry estimates derived from sequential whole-body PET using two versions of the OLINDA dosimetry program. Sequential whole-body PET scans were performed in 3 healthy subjects for 2 h after injection of 254 ± 77 MBq [11C]-UCB-J. Volumes of interest were...... hiện toàn bộ
First results from a high-resolution small animal PET insert for PET/MRI imaging
EJNMMI Physics - Tập 2 - Trang 1-1 - 2015
Andrew Goertzen, Greg Stortz, Jonathan Thiessen, Daryl Bishop, Muhammad Salman Khan, Piotr Kozlowski, Fabrice Retiere, Graham Schellenberg, Vesna Sossi, Christopher Thompson
Initial evaluation of a practical PET respiratory motion correction method in clinical simultaneous PET/MRI
EJNMMI Physics - Tập 1 - Trang 1-2 - 2014
Richard Manber, Kris Thielemans, Brian Hutton, Anna Barnes, Sebastien Ourselin, Simon Arridge, Celia O'Meara, David Atkinson
Intra- and inter-operator variability in MRI-based manual segmentation of HCC lesions and its impact on dosimetry
EJNMMI Physics - Tập 9 - Trang 1-16 - 2022
Elise C. Covert, Kellen Fitzpatrick, Justin Mikell, Ravi K. Kaza, John D. Millet, Daniel Barkmeier, Joseph Gemmete, Jared Christensen, Matthew J. Schipper, Yuni K. Dewaraja
The aim was to quantify inter- and intra-observer variability in manually delineated hepatocellular carcinoma (HCC) lesion contours and the resulting impact on radioembolization (RE) dosimetry. Ten patients with HCC lesions treated with Y-90 RE and imaged with post-therapy Y-90 PET/CT were selected for retrospective analysis. Three radiologists contoured 20 lesions manually on baseline multiphase ...... hiện toàn bộ
Impact of injection dose, post-reconstruction filtering, and collimator choice on image quality of myocardial perfusion SPECT using cadmium-zinc telluride detectors in the rat
EJNMMI Physics - Tập 2 - Trang 1-17 - 2015
Asuka Mizutani, Ichiro Matsunari, Masato Kobayashi, Kodai Nishi, Wataru Fujita, Yoshiharu Miyazaki, Stephan G Nekolla, Keiichi Kawai
The aims of this study were (1) to evaluate the impact of injection dose, post-reconstruction filtering, and collimator choice on image quality of myocardial perfusion single-photon emission computed tomography (SPECT) using cadmium-zinc telluride (CZT) detectors and (2) to determine how these factors affect measured infarct size in the in vivo rat. Twenty-four healthy and eight myocardial infarct...... hiện toàn bộ
Evaluation of the PETsys TOFPET2 ASIC in multi-channel coincidence experiments
EJNMMI Physics - Tập 8 - Trang 1-21 - 2021
Vanessa Nadig, David Schug, Bjoern Weissler, Volkmar Schulz
Aiming to measure the difference in arrival times of two coincident γ-photons with an accuracy in the order of 200ps, time-of-flight positron emission tomography systems commonly employ silicon photomultipliers (SiPMs) and high-resolution digitization electronics, application specific integrated circuits (ASICs). This work evaluates the performance of the TOFPET2 ASIC, released by PETsys Electroni...... hiện toàn bộ
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