Drugs
Công bố khoa học tiêu biểu
* Dữ liệu chỉ mang tính chất tham khảo
Sắp xếp:
Encorafenib: A Review in Metastatic Colorectal Cancer with a BRAF V600E Mutation
Drugs - Tập 81 - Trang 849-856 - 2021
Encorafenib (Braftovi®) is an oral small molecule BRAF inhibitor used in combination with cetuximab for the treatment of adult patients with metastatic colorectal cancer (mCRC) with a BRAF V600E mutation, who have received prior systemic therapy. In a clinical trial in adults with BRAF V600E-mutated mCRC who had disease progression after one or two previous regimens (BEACON CRC), encorafenib plus ......
Guidelines for the Use of Propafenone in Treating Supraventricular Arrhythmias
Drugs - Tập 50 - Trang 250-262 - 2012
Propafenone is a sodium channel blocking agent with a mild β- and calcium channel-blocking activity. Several controlled and noncomparative studies have documented its efficacy in a variety of supraventricular arrhythmias in both adults and children. Propafenone is comparable with other Vaughan-William class I antiarrhythmic drugs for acute conversion of atrial fibrillation. It is also comparable w......
Recent Antiplatelet Drug Trials in the Acute Coronary Syndromes
Drugs - Tập 56 - Trang 965-976 - 2012
This paper reviews the results of 4 recent clinical trials, Platelet Receptor inhibition for Ischaemic Syndrome Management (PRISM), Platelet Receptor inhibition for Ischaemic Syndrome Management in Patients Limited to very Unstable Signs and symptoms (PRISM-PLUS), Platelet IIb/IIIa Antagonist for the Reduction of Acute coronary syndrome events in a Global Organisation Network (PARAGON A), and Plat......
Cefotaxime A review of its Antibacterial Activity, Pharmacological Properties and Therapeutic Use
Drugs - Tập 25 Số 3 - Trang 223-289 - 1983
Anisoylated Plasminogen Streptokinase Activator Complex versus Placebo
Drugs - Tập 33 - Trang 261-267 - 2012
90 patients were enrolled into this preliminary multicentre study of the efficacy and safety of 30 units intravenous anisoylated plasminogen streptokinase activator complex (APSAC) compared with placebo in patients with acute myocardial infarction. 45 patients received APSAC and 45 placebo; the groups were similar for age, weight and site of infarction. There were significantly more women treated ......
Remoxipride
Drugs - Tập 40 - Trang 863-879 - 2012
Remoxipride is a substituted benzamide of the same class as sulpiride, and has a pharmacodynamic profile consistent with central antidopaminergic activity. It is a weak, but relatively selective, central dopamine D2-receptor antagonist and appears to have preferential affinity for extrastriatal dopamine D2-receptors. It also has marked affibrillationnity for central sigma receptors. Clinical data ......
Corticosteroid Resistance and Novel Anti-Inflammatory Therapies in Chronic Obstructive Pulmonary Disease
Drugs - Tập 72 - Trang 1299-1312 - 2012
Corticosteroids are widely used in the treatment of chronic obstructive pulmonary disease (COPD). However, in contrast to their use in mild-to-moderate asthma, they are much less effective in enhancing lung function and have little or no effect on controlling the underlying chronic inflammation. In most clinical trials in COPD patients, corticosteroids have shown little benefit as monotherapy, but......
Tổng số: 6,255
- 1
- 2
- 3
- 4
- 5
- 6
- 10