The biological benefits of lipids as sources of energy and precursors of cell
components have led to the evolution of a complex plasma lipoprotein transport
system, through which gram quantities of cholesterol, triglyceride, and
phospholipid pass each day. A wide variety of tissues make demands on this pool.
The adrenal glands and gonads avidly assimilate lipoprotein cholesterol for the
production... hiện toàn bộ
C. Louwrens Braal, Elisabeth M. Jongbloed, Saskia M. Wilting, Ron H. J. Mathijssen, Stijn L. W. Koolen, Agnes Jager
The cyclin-dependent kinase (CDK) 4/6 inhibitors belong to a new class of drugs
that interrupt proliferation of malignant cells by inhibiting progression
through the cell cycle. Three such inhibitors, palbociclib, ribociclib, and
abemaciclib were recently approved for breast cancer treatment in various
settings and combination regimens. On the basis of their impressive efficacy,
all three CDK4/6 i... hiện toàn bộ