Vitiligo: A Review Tập 236 Số 6 - Trang 571-592 - 2020
Christina Bergqvist, Khaled Ezzedine
Vitiligo, a common depigmenting skin disorder, has an estimated prevalence of
0.5–2% of the population worldwide. The disease is characterized by the
selective loss of melanocytes which results in typical nonscaly, chalky-white
macules. In recent years, considerable progress has been made in our
understanding of the pathogenesis of vitiligo which is now clearly classified as
an autoimmune disease.... hiện toàn bộ
Cardiovascular Disease and Risk Factors among Psoriasis Patients in Two US Healthcare Databases, 2001–2002 Tập 217 Số 1 - Trang 27-37 - 2008
Alexa B. Kimball, Don Robinson, Ying Wu, Cynthia Guzzo, Newman Yeilding, Clark Paramore, Kathy Fraeman, M Bala
Background: Cardiovascular diseases or risk factors (CVDR) seem to be
more common in psoriasis patients than in the general population.
Objective: We assessed the relationship of psoriasis with CVDR by
analysis of healthcare claims data using a cross-sectional, prevalence-based
study design. Patients and Methods: The IMS Health and MarketScan® claims
databases were used to ide... hiện toàn bộ
Cornified Cell Envelope Tập 180 Số 4 - Trang 201-211 - 1990
Daniel Hohl
The cornified cell envelope (CE) is a highly insoluble structure on the inside
of the plasma membrane of terminally differentiated keratinocytes. The cellular
and molecular biology of the CE is outlined and new areas of research involving
the CE are reviewed focussing on morphological and biochemical connections, the
sequential gene expression during terminal differentiation, the interaction of
li... hiện toàn bộ
Randomized Double-Blind Multicenter Study Comparing Acitretin-PUVA, Etretinate-PUVA and Placebo-PUVA in the Treatment of Severe Psoriasis Tập 177 Số 4 - Trang 218-224 - 1988
J H Saurat, J.-M. Geiger, P Amblard, J.-C. Béani, A Boulanger, A Claudy, E. Frenk, J J Guilhou, E Grosshans, Y. Mérot
A randomized double-blind study was designed with 65 patients in order to
clarify two points: (1) does addition of a retinoid to psoralen-ultra violet A
photochemotherapy (PUVA) of severe psoriasis decrease the UVA energy required to
achieve remission, and (2) is there a difference between two retinoids, i.e.
etretinate and acitretin. Acitretin-PUVA treatment was significantly superior to
placebo-... hiện toàn bộ
Mu-Opiate Receptor and Beta-Endorphin Expression in Nerve Endings and Keratinocytes in Human Skin Tập 209 Số 3 - Trang 183-189 - 2004
Mei Bigliardi‐Qi, Lazar T. Sumanovski, S.A. Büchner, T Rufli, Paul L. Bigliardi
We have previously shown that human epidermal keratinocytes express a
functionally active µ-opiate receptor, which adds a new dimension to the
recently developed research in neuroimmunodermatology and neurogenic
inflammation in skin diseases. Human keratinocytes specifically bind and also
produce β-endorphin, the endogenous µ-opiate receptor ligand. Using confocal
imaging microscopy, we could now ... hiện toàn bộ
Acitretin (Ro 10-1670, Etretin): Overall Evaluation of Clinical Studies Tập 176 Số 4 - Trang 182-190 - 1988
J.-M. Geiger, B M Czarnetzki
Acitretin (Ro 10-1670, etretin) is the free acid derivative of etretinate. This
compound possesses a much shorter half-life of elimination than etretinate and
was therefore proposed for clinical development. A total of 635 patients with
various dermatoses were studied in 12 main clinical trials performed in Europe
and in the United States. It was shown that acitretin is effective in the
treatment ... hiện toàn bộ
Survey of 200 Cases of Sporotrichosis Tập 172 Số 4 - Trang 209-213 - 1986
M. Itoh, Shinichiro Okamoto, Hideo Kariya
A survey of 200 cases of sporotrichosis seen at the Dermatology Clinic of Chiba
University Hospital from May 1965 to August 1983 is reported. The proportion of
cases with sporotrichosis to the total number of outpatients was 0.15%. A higher
percentage of cases fell into the less than 12-year-old or more than 40-year-old
age groups. The male to female ratio was 1:2. Half of the cases occurred in
fa... hiện toàn bộ