Dementia and Geriatric Cognitive Disorders
SCIE-ISI SCOPUS (1990-1992,1994-2023)
1421-9824
1420-8008
Thụy Sĩ
Cơ quản chủ quản: S. Karger AG , KARGER
Lĩnh vực:
Psychiatry and Mental HealthCognitive NeuroscienceGeriatrics and Gerontology
Các bài báo tiêu biểu
Midlife Serum Cholesterol and Increased Risk of Alzheimer’s and Vascular Dementia Three Decades Later<i>Aims:</i> To investigate midlife cholesterol in relation to Alzheimer’s disease (AD) and vascular dementia (VaD) in a large multiethnic cohort of women and men. <i>Methods:</i> The Kaiser Permanente Northern California Medical Group (healthcare delivery organization) formed the database for this study. The 9,844 participants underwent detailed health evaluations ... ... hiện toàn bộ
Tập 28 Số 1 - Trang 75-80 - 2009
The Bayer Activities of Daily Living Scale (B-ADL)The Bayer Activities of Daily Living Scale (B-ADL) has been developed on an international basis to assess deficits in the performance of everyday activities. The scale’s main target group is community dwelling patients who suffer mild cognitive impairment or mild-to-moderate dementia. It comprises 25 items and takes the form of a questionnaire to be completed by a caregiver or other inform... ... hiện toàn bộ
Tập 9 Số Suppl. 2 - Trang 20-26 - 1998
Improvement of Episodic Memory in Persons with Mild Cognitive Impairment and Healthy Older Adults: Evidence from a Cognitive Intervention ProgramThe efficacy of cognitive training was assessed in persons with mild cognitive impairment (MCI) and persons with normal cognitive aging. Forty-seven participants were included in this study: 28 with MCI and 17 controls. Twenty-one participants received intervention (20 MCI and 9 controls) and 16 participants (8 MCI and 8 controls) received no intervention (waiting-list group). The interven... ... hiện toàn bộ
Tập 22 Số 5-6 - Trang 486-499 - 2006
Treatment of Alzheimer’s Disease with ClioquinolAs heavy metal ions may be implicated in the formation of senile plaques in Alzheimer-afflicted brains, treatment with clioquinol was tested in 20 patients with Alzheimer’s disease. Clioquinol is a chelator that crosses the blood-brain barrier and has greater affinity for zinc and copper ions than for calcium and magnesium ions. Treatment was given for 21 days at doses of 20 mg/day to 10 p... ... hiện toàn bộ
Tập 12 Số 6 - Trang 408-414 - 2001
Update on the Neuropathogenesis of DeliriumDelirium has been considered a syndrome of generalized dysfunction of higher cortical functions due to its breadth of symptoms and associated diffuse slowing on electroencephalogram. Advances in neuropsychiatry have revealed differences between brain regions, including the hemispheres, which may underlie the constellation of symptoms among different psychiatric disorders. For example, diff... ... hiện toàn bộ
Tập 10 Số 5 - Trang 330-334 - 1999
Early-Onset Dementia: Frequency and Causes Compared to Late-Onset Dementia<i>Background:</i> Research on the epidemiology of dementia has focused on the elderly. Few investigations have studied differences in etiologic frequencies between early-onset dementia (EOD), with onset at an age of less than 65 years old, and the more common late-onset disorder. <i>Objectives:</i> To determine relative frequencies and characteristics of EOD versus... ... hiện toàn bộ
Tập 21 Số 2 - Trang 59-64 - 2006
Patient and Caregiver Perspectives of Quality of Life in Dementia<i>Background/Aims:</i> Behavioural and psychological symptoms have a high prevalence amongst patients with dementia and can be a significant source of distress to both patients and carers. The present study explored the relationships between quality of life and behavioural and psychological symptoms in dementia (BPSD) from both patient and carer perspectives. Contextual factor... ... hiện toàn bộ
Tập 26 Số 2 - Trang 138-146 - 2008
Subjective Memory Complaints: Presence, Severity and Future Outcome in Normal Older Subjects<i>Background/Aims:</i> Subjective memory complaint (SMC) in normal individuals may predict future cognitive decline. The goal of this study was to examine whether the probability of decline increases with growing intensity of complaint. <i>Methods:</i> Normal subjects over the age of 50 years were included in a longitudinal retrospective study (mean follow-up time ... ... hiện toàn bộ
Tập 24 Số 3 - Trang 177-184 - 2007
Measurement of Thirteen Biological Markers in CSF of Patients with Alzheimer’s Disease and Other DementiasCerebrospinal fluid (CSF) biological markers may be of valuable help in the diagnosis of dementia. The aim of the present study was to evaluate CSF levels of 13 potential biomarkers in patients with Alzheimer’s disease (AD), frontotemporal lobe dementia, alcohol dementia, major depression and control patients without any neuropsychiatric disease. The study was performed using β-amyloid 1–4... ... hiện toàn bộ
Tập 21 Số 1 - Trang 9-15 - 2006
Rapid Progression from Mild Cognitive Impairment to Alzheimer’s Disease in Subjects with Elevated Levels of Tau in Cerebrospinal Fluid and the <i>APOE </i>ε<i>4</i>/ε<i>4</i> Genotype<i>Background/Aims:</i> Increased cerebrospinal fluid (CSF) tau, decreased CSF amyloid-β42 (Aβ42) and the apolipoprotein E gene <i>(APOE) </i>ε<i>4</i> allele predict progression from mild cognitive impairment (MCI) to Alzheimer’s disease (AD). Here, we investigated these markers to assess their predictive value and influence on the rate of disease progr... ... hiện toàn bộ
Tập 27 Số 5 - Trang 458-464 - 2009