Current Osteoporosis Reports

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Use of Strontium as a Treatment Method for Osteoporosis
Current Osteoporosis Reports - Tập 9 Số 1 - Trang 25-30 - 2011
Bernard Cortet
Type 2 Diabetes Mellitus and Vertebral Fracture Risk
Current Osteoporosis Reports - - 2021
Fjorda Koromani, Samuel Ghatan, Mandy van Hoek, M. Carola Zillikens, Edwin H.G. Oei, Fernando Rivadeneira, Ling Oei
Abstract Purpose of Review The purpose of this review is to summarize the recently published evidence concerning vertebral fracture risk in individuals with diabetes mellitus. Recent Findings ... hiện toàn bộ
Genetic Pleiotropy of Bone-Related Phenotypes: Insights from Osteoporosis
Current Osteoporosis Reports - Tập 18 - Trang 606-619 - 2020
M. A. Christou, E. E. Ntzani, D. Karasik
We summarize recent evidence on the shared genetics within and outside the musculoskeletal system (mostly related to bone density and osteoporosis). Osteoporosis is determined by an interplay between multiple genetic and environmental factors. Significant progress has been made regarding its genetic background revealing a number of robustly validated loci and respective pathways. However, pleiotro...... hiện toàn bộ
Monitoring osteoporosis therapies
Current Osteoporosis Reports - Tập 5 Số 1 - Trang 38-43 - 2007
Paul D. Miller
Clinical relevance of diagnosing vertebral fractures by vertebral fracture assessment
Current Osteoporosis Reports - Tập 7 - Trang 103-106 - 2009
Marleen S. van Brussel, Willem F. Lems
Low bone mineral density and the presence of vertebral fractures are independent predictors for future vertebral and non-vertebral fractures. Combining the conventional measurement of bone mineral density of spine and hips with the morphometry of the thoracal and lumbar vertebrae on lateral images using dual energy x-ray absorptiometry scanners, a technique called vertebral fracture assessment, fa...... hiện toàn bộ
The relationship between bone mineral density and fracture risk
Current Osteoporosis Reports - Tập 3 - Trang 57-63 - 2005
Michael R. McClung
Osteoporosis is a disorder characterized by low bone density and impaired bone strength which is an important risk factor for fracture in older adults. The diagnosis of osteoporosis in postmenopausal women is now based on bone density testing by dual energy x-ray absorptiometry but not other methodologies. However, a specific but arbitrary diagnostic threshold must be distinguished from a strategy...... hiện toàn bộ
The Interrelationship Between Diabetes, IL-17 and Bone Loss
Current Osteoporosis Reports - Tập 18 - Trang 23-31 - 2020
Zhen Huang, Xiyan Pei, Dana T. Graves
Diabetes has a detrimental effect on bone, increasing the risk of fracture and formation of osteolytic lesions such as those seen in periodontitis. Several diabetic complications are caused by diabetes-enhanced inflammation. This review examines mechanisms by which IL-17 contributes to diabetes-enhanced periodontitis and other effects of IL-17 on bone. IL-17 upregulates anti-bacterial defenses, ye...... hiện toàn bộ
Fracture Risk Assessment: State of the Art, Methodologically Unsound, or Poorly Reported?
Current Osteoporosis Reports - Tập 10 - Trang 199-207 - 2012
Gary S. Collins, Karl Michaëlsson
Osteoporotic fractures, including hip fractures, are a global health concern associated with significant morbidity and mortality as well as a major economic burden. Identifying individuals who are at an increased risk of osteoporotic fracture is an important challenge to be resolved. Recently, multivariable prediction tools have been developed to assist clinicians in the management of their patien...... hiện toàn bộ
Periosteal Skeletal Stem and Progenitor Cells in Bone Regeneration
Current Osteoporosis Reports - Tập 20 - Trang 334-343 - 2022
Simon Perrin, Céline Colnot
The periosteum, the outer layer of bone, is a major source of skeletal stem/progenitor cells (SSPCs) for bone repair. Here, we discuss recent findings on the characterization, role, and regulation of periosteal SSPCs (pSSPCs) during bone regeneration. Several markers have been described for pSSPCs but lack tissue specificity. In vivo lineage tracing and transcriptomic analyses have improved our un...... hiện toàn bộ
Peripheral Neuropathy as a Component of Skeletal Disease in Diabetes
Current Osteoporosis Reports - Tập 17 - Trang 256-269 - 2019
Alec T. Beeve, Jennifer M. Brazill, Erica L. Scheller
The goal of this review is to explore clinical associations between peripheral neuropathy and diabetic bone disease and to discuss how nerve dysfunction may contribute to dysregulation of bone metabolism, reduced bone quality, and fracture risk. Diabetic neuropathy can decrease peripheral sensation (sensory neuropathy), impair motor coordination (motor neuropathy), and increase postural hypotensio...... hiện toàn bộ
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