New insights into angiopoietin-like proteins in lipid metabolism and cardiovascular disease riskCurrent Opinion in Lipidology - Tập 30 Số 3 - Trang 205-211 - 2019
Sander Kersten
Purpose of review
The angiopoietin-like proteins (ANGPTLs), consisting of ANGPTL3, ANGPTL4, and ANGPTL8, have gained significant interest for their role as inhibitors of lipoprotein lipase (LPL) and for their potential as therapeutic targets for correcting dyslipidemia. This review provides an overview of the most relevant new ins...... hiện toàn bộ
Hypobetalipoproteinemia and abetalipoproteinemia: liver disease and cardiovascular diseaseCurrent Opinion in Lipidology - Tập 31 Số 2 - Trang 49-55 - 2020
Francine K. Welty
Purpose of review
Several mutations in the apolipoprotein (apo) B, proprotein convertase subtilisin kexin 9 (PCSK9) and microsomal triglyceride transfer protein genes result in low or absent levels of apoB and LDL cholesterol (LDL-C) in plasma which cause familial hypobetalipoproteinemia (FHBL) and abetalipoproteinemia (ABL). Muta...... hiện toàn bộ
Lipoprotein receptorsCurrent Opinion in Lipidology - Tập 4 Số 3 - Trang 205-209 - 1993
Wolfgang J. Schneider, Johannes Nimpf