New insights into angiopoietin-like proteins in lipid metabolism and cardiovascular disease riskCurrent Opinion in Lipidology - Tập 30 Số 3 - Trang 205-211 - 2019
Sander Kersten
Purpose of review The angiopoietin-like proteins (ANGPTLs), consisting of
ANGPTL3, ANGPTL4, and ANGPTL8, have gained significant interest for their role
as inhibitors of lipoprotein lipase (LPL) and for their potential as therapeutic
targets for correcting dyslipidemia. This review provides an overview of the
most relevant new insights on the connection between ANGPTLs, plasma lipids, and
coronary... hiện toàn bộ
Hypobetalipoproteinemia and abetalipoproteinemia: liver disease and cardiovascular diseaseCurrent Opinion in Lipidology - Tập 31 Số 2 - Trang 49-55 - 2020
Francine K. Welty
Purpose of review Several mutations in the apolipoprotein (apo) B, proprotein
convertase subtilisin kexin 9 (PCSK9) and microsomal triglyceride transfer
protein genes result in low or absent levels of apoB and LDL cholesterol (LDL-C)
in plasma which cause familial hypobetalipoproteinemia (FHBL) and
abetalipoproteinemia (ABL). Mutations in the angiopoietin-like protein 3 ANGPTL3
gene cause familial... hiện toàn bộ
Lipoprotein receptorsCurrent Opinion in Lipidology - Tập 4 Số 3 - Trang 205-209 - 1993
Wolfgang J. Schneider, Johannes Nimpf