Hypobetalipoproteinemia and abetalipoproteinemia: liver disease and cardiovascular diseaseCurrent Opinion in Lipidology - Tập 31 Số 2 - Trang 49-55 - 2020
Francine K. Welty
Purpose of review
Several mutations in the apolipoprotein (apo) B, proprotein convertase subtilisin kexin 9 (PCSK9) and microsomal triglyceride transfer protein genes result in low or absent levels of apoB and LDL cholesterol (LDL-C) in plasma which cause familial hypobetalipoproteinemia (FHBL) and abetalipoproteinemia (ABL). Muta...... hiện toàn bộ