Regulation of lipid metabolism by angiopoietin-like proteins
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Mattijssen, 2012, Regulation of triglyceride metabolism by Angiopoietin-like proteins, Biochim Biophys Acta, 1821, 782, 10.1016/j.bbalip.2011.10.010
Santulli, 2014, Angiopoietin-like proteins: a comprehensive look, Front Endocrinol (Lausanne, 5, 5, 10.3389/fendo.2014.00004
Peloso, 2014, Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 Whites and Blacks, Am J Hum Genet, 94, 223, 10.1016/j.ajhg.2014.01.009
Quagliarini, 2012, Atypical angiopoietin-like protein that regulates ANGPTL3, Proc Natl Acad Sci USA, 109, 19751, 10.1073/pnas.1217552109
Yoshida, 2002, Angiopoietin-like protein 4 is a potent hyperlipidemia-inducing factor in mice and inhibitor of lipoprotein lipase, J Lipid Res, 43, 1770, 10.1194/jlr.C200010-JLR200
Shimizugawa, 2002, ANGPTL3 decreases very low density lipoprotein triglyceride clearance by inhibition of lipoprotein lipase, J Biol Chem, 277, 33742, 10.1074/jbc.M203215200
Mattijssen, 2013, Angptl4 serves as an endogenous inhibitor of intestinal lipid digestion, Mol Metab, 3, 135, 10.1016/j.molmet.2013.11.004
Lichtenstein, 2007, Angptl4 upregulates cholesterol synthesis in liver via inhibition of LPL- and HL-dependent hepatic cholesterol uptake, Arterioscler Thromb Vasc Biol, 27, 2420, 10.1161/ATVBAHA.107.151894
Shimamura, 2007, Angiopoietin-like protein3 regulates plasma HDL cholesterol through suppression of endothelial lipase, Arterioscler Thromb Vasc Biol, 27, 366, 10.1161/01.ATV.0000252827.51626.89
Fujimoto, 2006, Angptl3-null mice show low plasma lipid concentrations by enhanced lipoprotein lipase activity, Exp Anim, 55, 27, 10.1538/expanim.55.27
Köster, 2005, Transgenic angiopoietin-like (angptl)4 overexpression and targeted disruption of angptl4 and angptl3: regulation of triglyceride metabolism, Endocrinology, 146, 4943, 10.1210/en.2005-0476
Romeo, 2009, Rare loss-of-function mutations in ANGPTL family members contribute to plasma triglyceride levels in humans, J Clin Nutr, 119, 70
Teslovich, 2010, Biological, clinical and population relevance of 95 loci for blood lipids, Nature, 466, 707, 10.1038/nature09270
Hegele, 2009, A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia, Hum Mol Genet, 18, 4189, 10.1093/hmg/ddp361
Kathiresan, 2009, Common variants at 30 loci contribute to polygenic dyslipidemia, Nat Gen, 41, 56, 10.1038/ng.291
Kathiresan, 2008, Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans, Nat Genet, 40, 189, 10.1038/ng.75
Willer, 2008, Newly identified loci that influence lipid concentrations and risk of coronary artery disease, Nat Genet, 40, 161, 10.1038/ng.76
De Castro-Orós, 2014, Common genetic variants contribute to primary hypertriglyceridemia without differences between familial combined hyperlipidemia and isolated hypertriglyceridemia, Circ Cardiovasc Genet, 7, 814, 10.1161/CIRCGENETICS.114.000522
Robciuc, 2013, Angptl3 deficiency is associated with increased insulin sensitivity, lipoprotein lipase activity, and decreased serum free fatty acids, Arterioscler Thromb Vasc Biol, 33, 1706, 10.1161/ATVBAHA.113.301397
Musunuru, 2010, Exome sequencing, ANGPTL3 mutations, and familial combined hypolipidemia, N Engl J Med, 363, 2220, 10.1056/NEJMoa1002926
Gusarova, 2015, ANGPTL3 blockade with a human monoclonal antibody reduces plasma lipids in dyslipidemic mice and monkeys, J Lipid Res, 56, 1308, 10.1194/jlr.M054890
Ishida, 2003, Endothelial lipase is a major determinant of HDL level, J Clin Invest, 111, 347, 10.1172/JCI16306
McCoy, 2002, Characterization of the lipolytic activity of endothelial lipase, J Lipid Res, 43, 921, 10.1016/S0022-2275(20)30466-1
Yasuda, 2010, Update on the role of endothelial lipase in high-density lipoprotein metabolism, reverse cholesterol transport, and atherosclerosis, Circ J, 74, 2263, 10.1253/circj.CJ-10-0934
Mehta, 2014, Differential association of plasma angiopoietin-like proteins 3 and 4 with lipid and metabolic traits, Arterioscler Thromb Vasc Biol, 34, 1057, 10.1161/ATVBAHA.113.302802
Robciuc, 2010, Quantitation of serum angiopoietin-like proteins 3 and 4 in a Finnish population sample, J Lipid Res, 51, 824, 10.1194/jlr.M002618
Hatsuda, 2007, Association between plasma angiopoietin-like protein 3 and arterial wall thickness in healthy subjects, J Vasc Res, 44, 61, 10.1159/000098153
Wang, 2015, Hepatic ANGPTL3 regulates adipose tissue energy homeostasis, Proc Natl Acad Sci, 112, 11630, 10.1073/pnas.1515374112
Olivecrona, 2010, Triglyceride lipases and atherosclerosis, Curr Opin Lipidol, 6, 291, 10.1097/00041433-199510000-00009
Wang, 2015, Inactivation of ANGPTL3 reduces hepatic VLDL-triglyceride secretion, J Lipid Res, 56, 1296, 10.1194/jlr.M054882
Shimamura, 2003, Angiopoietin-like protein 3, a hepatic secretory factor, activates lipolysis in adipocytes, Biochem Biophys Res Commun, 301, 604, 10.1016/S0006-291X(02)03058-9
Merkel, 1998, Catalytically inactive lipoprotein lipase expression in muscle of transgenic mice increases very low density lipoprotein uptake: direct evidence that lipoprotein lipase bridging occurs in vivo, Proc Natl Acad Sci U S A, 95, 13841, 10.1073/pnas.95.23.13841
Heeren, 2002, Endothelial-derived lipoprotein lipase is bound to postprandial triglyceride-rich lipoproteins and mediates their hepatic clearance in vivo, J Mol Med, 80, 576, 10.1007/s00109-002-0351-5
Kroupa, 2012, Linking nutritional regulation of Angptl4, Gpihbp1, and Lmf1 to lipoprotein lipase activity in rodent adipose tissue, BMC Physiol, 12, 13, 10.1186/1472-6793-12-13
Kersten, 2000, Characterization of the fasting-induced adipose factor FIAF, a novel peroxisome proliferator-activated receptor target gene, J Biol Chem, 275, 28488, 10.1074/jbc.M004029200
Dijk, 2015, ANGPTL4 mediates shuttling of lipid fuel to brown adipose tissue during sustained cold exposure, Elife, 4, ii, 10.7554/eLife.08428
Mandard, 2004, The direct peroxisome proliferator-activated receptor target fasting-induced adipose factor (FIAF/PGAR/ANGPTL4) is present in blood plasma as a truncated protein that is increased by fenofibrate treatment, J Biol Chem, 279, 34411, 10.1074/jbc.M403058200
Yoon, 2000, Peroxisome proliferator-activated receptor gamma target gene encoding a novel angiopoietin-related protein associated with adipose differentiation, Mol Cell Biol, 20, 5343, 10.1128/MCB.20.14.5343-5349.2000
Georgiadi, 2010, Induction of cardiac Angptl4 by dietary fatty acids is mediated by peroxisome proliferator-activated receptor beta/delta and protects against fatty acid-induced oxidative stress, Circ Res, 106, 1712, 10.1161/CIRCRESAHA.110.217380
Romeo, 2007, Population-based resequencing of ANGPTL4 uncovers variations that reduce triglycerides and increase HDL, Nat Genet, 39, 513, 10.1038/ng1984
Talmud, 2008, ANGPTL4 E40K and T266 M: effects on plasma triglyceride and HDL levels, postprandial responses, and CHD risk, Arter Thromb Vasc Biol, 28, 2319, 10.1161/ATVBAHA.108.176917
Nettleton, 2008, Longitudinal changes in triglycerides according to ANGPTL4[E40K] genotype and longitudinal body weight change in the atherosclerosis risk in communities study, Ann Epidemiol, 18, 842, 10.1016/j.annepidem.2008.07.004
Mandard, 2006, The fasting-induced adipose factor/angiopoietin-like protein 4 is physically associated with lipoproteins and governs plasma lipid levels and adiposity, J Biol Chem, 281, 934, 10.1074/jbc.M506519200
Lichtenstein, 2010, Angptl4 protects against severe proinflammatory effects of saturated fat by inhibiting fatty acid uptake into mesenteric lymph node macrophages, Cell Metab, 12, 580, 10.1016/j.cmet.2010.11.002
Musunuru, 2016, Surprises from genetic analyses of lipid risk factors for atherosclerosis, Circ Res, 118, 579, 10.1161/CIRCRESAHA.115.306398
Catoire, 2014, Fatty acid-inducible ANGPTL4 governs lipid metabolic response to exercise, Proc Natl Acad Sci U S A, 111, E1043, 10.1073/pnas.1400889111
Dijk, 2014, Regulation of lipoprotein lipase by Angptl4, Trends Endocrinol Metab, 25, 146, 10.1016/j.tem.2013.12.005
Clement, 2014, Circulating angiopoietin-like 4 links proteinuria with hypertriglyceridemia in nephrotic syndrome, Nat Med, 20, 37, 10.1038/nm.3396
Smart-Halajko, 2010, The relationship between plasma angiopoietin-like protein 4 levels, angiopoietin-like protein 4 genotype, and coronary heart disease risk, Arterioscler Thromb Vasc Biol, 30, 2277, 10.1161/ATVBAHA.110.212209
Robciuc, 2011, Serum angiopoietin-like 4 protein levels and expression in adipose tissue are inversely correlated with obesity in monozygotic twins, J Lipid Res, 52, 1575, 10.1194/jlr.P015867
Brands, 2013, Omega-3 long-chain fatty acids strongly induce angiopoietin-like 4 in humans, J Lipid Res, 54, 615, 10.1194/jlr.M030049
van Raalte, 2012, Angiopoietin-like protein 4 is differentially regulated by glucocorticoids and insulin in vitro and in vivo in healthy humans, Exp Clin Endocrinol, 120, 598, 10.1055/s-0032-1321864
Jonker, 2013, Dietary modulation of plasma angiopoietin-like protein 4 concentrations in healthy volunteers and in patients with type 2 diabetes, J Clin Nutr, 97, 255, 10.3945/ajcn.112.043687
Adhikary, 2013, Inverse PPARβ/δ agonists suppress oncogenic signaling to the ANGPTL4 gene and inhibit cancer cell invasion, Oncogene, 32, 5241, 10.1038/onc.2012.549
Robciuc, 2012, Angiopoietin-like 4 mediates PPAR delta effect on lipoprotein lipase-dependent fatty acid uptake but not on beta-oxidation in myotubes, PLoS One, 7, e46212, 10.1371/journal.pone.0046212
Nilsson, 2012, Triacylglycerol-rich lipoproteins protect lipoprotein lipase from inactivation by ANGPTL3 and ANGPTL4, Biochim Biophys Acta, 1821, 1370, 10.1016/j.bbalip.2012.06.003
Makoveichuk, 2013, Inactivation of lipoprotein lipase in 3T3-L1 adipocytes by angiopoietin-like protein 4 requires that both proteins have reached the cell surface, Biochem Biophys Res Commun, 441, 941, 10.1016/j.bbrc.2013.11.013
Makoveichuk, 2012, Inactivation of lipoprotein lipase occurs on the surface of THP-1 macrophages where oligomers of angiopoietin-like protein 4 are formed, Biochem Biophys Res Commun, 425, 138, 10.1016/j.bbrc.2012.07.048
Chi, 2015, Angiopoietin-like 4 modifies the interactions between lipoprotein lipase and its endothelial cell transporter GPIHBP1, J Biol Chem, 290, 11865, 10.1074/jbc.M114.623769
Davies, 2012, Assessing mechanisms of GPIHBP1 and lipoprotein lipase movement across endothelial cells, J Lipid Res, 53, 2690, 10.1194/jlr.M031559
Korecka, 2013, ANGPTL4 expression induced by butyrate and rosiglitazone in human intestinal epithelial cells utilize independent pathways, Am J Physiol Gastrointest Liver Physiol, 304, G1025, 10.1152/ajpgi.00293.2012
Alex, 2013, Short-chain fatty acids stimulate angiopoietin-like 4 synthesis in human colon adenocarcinoma cells by activating peroxisome proliferator-activated receptor γ, Mol Cell Biol, 33, 1303, 10.1128/MCB.00858-12
Alex, 2013, ANGPTL4 is produced by entero-endocrine cells in the human intestinal tract, Histochem Cell Biol, 141, 383, 10.1007/s00418-013-1157-y
Aronsson, 2010, Decreased fat storage by Lactobacillus paracasei is associated with increased levels of angiopoietin-like 4 protein (ANGPTL4), PLoS One, 5, e13087, 10.1371/journal.pone.0013087
Bäckhed, 2007, The gut microbiota as an environmental factor that regulates fat storage, Proc Natl Acad Sci USA, 101, 15718, 10.1073/pnas.0407076101
El Aidy, 2013, The gut microbiota elicits a profound metabolic reorientation in the mouse jejunal mucosa during conventionalisation, Gut, 62, 1306, 10.1136/gutjnl-2011-301955
Bäckhed, 2007, Mechanisms underlying the resistance to diet-induced obesity in germ-free mice, Proc Natl Acad Sci U S A, 104, 979, 10.1073/pnas.0605374104
Zhang, 2012, Lipasin, a novel nutritionally-regulated liver-enriched factor that regulates serum triglyceride levels, Biochem Biophys Res Commun, 424, 786, 10.1016/j.bbrc.2012.07.038
Ren, 2012, Identification of RIFL, a novel adipocyte-enriched insulin target gene with a role in lipid metabolism, Am J Physiol Endocrinol Metab, 303, E334, 10.1152/ajpendo.00084.2012
Fenzl, 2014, Circulating betatrophin correlates with atherogenic lipid profiles but not with glucose and insulin levels in insulin-resistant individuals, Diabetologia, 57, 1204, 10.1007/s00125-014-3208-x
Fu, 2014, Elevated circulating lipasin/betatrophin in human type 2 diabetes and obesity, Sci Rep, 4, 5013, 10.1038/srep05013
Ebert, 2014, Circulating angiopoietin-like protein 8 is independently associated with fasting plasma glucose and type 2 diabetes mellitus, J Clin Endocrinol Metab, 99, E2510, 10.1210/jc.2013-4349
Fu, 2014, An explanation for recent discrepancies in levels of human circulating betatrophin, Diabetologia, 57, 2232, 10.1007/s00125-014-3346-1
Gómez-Ambrosi, 2014, Circulating betatrophin concentrations are decreased in human obesity and type 2 diabetes, J Clin Endocrinol Metab, 99, E2004, 10.1210/jc.2014-1568
Fu, 2015, A lipasin/Angptl8 monoclonal antibody lowers mouse serum triglycerides involving increased postprandial activity of the cardiac lipoprotein lipase, Sci Rep, 5, 18502, 10.1038/srep18502
Wang, 2013, Mice lacking ANGPTL8 (Betatrophin) manifest disrupted triglyceride metabolism without impaired glucose homeostasis, Proc Natl Acad Sci U S A, 110, 16109, 10.1073/pnas.1315292110
Fu, 2013, Lipasin, thermoregulated in brown fat, is a novel but atypical member of the angiopoietin-like protein family, Biochem Biophys Res Commun, 430, 1126, 10.1016/j.bbrc.2012.12.025
Yi, 2013, Betatrophin: a hormone that controls pancreatic β cell proliferation, Cell, 153, 747, 10.1016/j.cell.2013.04.008
Jiao, 2014, Elevated mouse hepatic betatrophin expression does not increase human -cell replication in the transplant setting, Diabetes, 63, 1283, 10.2337/db13-1435
Cox, 2015, Angiopoietin-like protein 8 (ANGPTL8)/betatrophin overexpression does not increase beta cell proliferation in mice, Diabetologia, 8, 1523, 10.1007/s00125-015-3590-z
Gusarova, 2014, ANGPTL8/betatrophin does not control pancreatic beta cell expansion, Cell, 159, 691, 10.1016/j.cell.2014.09.027
Clapham, 2016, A null mutation in ANGPTL8 does not associate with either plasma glucose or type 2 diabetes in humans, BMC Endocr Disord, 16, 7, 10.1186/s12902-016-0088-8
Yi, 2014, Perspectives on the activities of ANGPTL8/betatrophin, Cell, 159, 467, 10.1016/j.cell.2014.09.028
Gray, 2012, Angiopoietin-like 4 (Angptl4) protein is a physiological mediator of intracellular lipolysis in murine adipocytes, J Biol Chem, 287, 8444, 10.1074/jbc.M111.294124
Kersten, 2014, Physiological regulation of lipoprotein lipase, Biochim Biophys Acta, 1841, 919, 10.1016/j.bbalip.2014.03.013