Control of the oocyte-to-embryo transition by the ubiquitin–proteolytic system in mouse and C. elegansCurrent Opinion in Cell Biology - Tập 22 - Trang 758 - 2010
Terret Marie-Emilie, Verlhac Marie-Hélène, Pintard Lionel
In metazoans the oocyte-to-embryo transition occurs in the absence of mRNA transcription and relies entirely on maternally provided mRNA and proteins. We review here recent findings illustrating the importance of degradation of key proteins allowing essential cell cycle transitions as well as important remodelling of the oocyte to produce a totipotent zygote. By following the chronological order o...... hiện toàn bộ