Human Pluripotent Stem Cell-Derived Retinal Ganglion Cells: Applications for the Study and Treatment of Optic NeuropathiesCurrent Ophthalmology Reports - Tập 3 - Trang 200-206 - 2015
Jessica A. Cooke, Jason S. Meyer
Retinal ganglion cells (RGCs) are highly specialized neuronal cells located in the innermost layer of the retina and serve to relay visual information to the brain, with their axons collectively forming the optic nerve. Loss or damage to the RGCs results in visual impairment and ultimately blindness. Several diseases affect the RGCs exclusively, the most common being glaucoma. Even though the mech...... hiện toàn bộ
Extraocular Muscle Repair and RegenerationCurrent Ophthalmology Reports - Tập 5 - Trang 207-215 - 2017
Mayank Verma, Krysta R. Fitzpatrick, Linda K. McLoon
The goal of this review is to summarize the unique regenerative milieu within mature mammalian extraocular muscles (EOMs). This will aid in understanding disease propensity for and sparing of EOMs in skeletal muscle diseases as well as the recalcitrance of the EOM to injury. The EOMs continually remodel throughout life and contain an extremely enriched number of myogenic precursor cells that diffe...... hiện toàn bộ
Y học tái sinh trong giác mạc Dịch bởi AI Current Ophthalmology Reports - Tập 5 - Trang 187-192 - 2017
Fiona C. Simpson, May Griffith
Bệnh giác mạc ảnh hưởng đến 12,7 triệu người trên toàn cầu, và liệu pháp tiêu chuẩn hiện tại sử dụng giác mạc từ người hiến tặng (HDC) ở những bệnh nhân có nguy cơ thấp hoặc keratoprosthesis ở những bệnh nhân có nguy cơ cao dễ bị từ chối ghép. Các kỹ thuật mới hiện đang được nghiên cứu nhằm tái tạo mô giác mạc để cung cấp một phương pháp điều trị hiệu quả hơn cho tình trạng mù giác mạc. Nghiên cứu...... hiện toàn bộ
#giác mạc #y học tái sinh #liệu pháp tế bào #ghép đồng loại #khung nhân tạo #khung đa lớp
The Immune System and AMDCurrent Ophthalmology Reports - Tập 2 - Trang 14-19 - 2014
Paul A. Frederick, Mark E. Kleinman
Age-related macular degeneration is a complex, multifactorial disease that has yet to be completely understood. Significant efforts in the basic and clinical sciences have unveiled numerous areas that appear to be critical in the pathogenesis of this disease. The alternative complement pathway, immune cell activation, and autoimmunity are all emerging as important themes in the suspected immunolog...... hiện toàn bộ
Management Strategies to Reduce Risk of Postoperative InfectionsCurrent Ophthalmology Reports - Tập 1 - Trang 161-168 - 2013
Anat Galor, Raquel Goldhardt, Sarah R. Wellik, Ninel Z. Gregori, Harry W. Flynn
Postoperative infections, although rare, are still of great concern to the ophthalmologist. The incidence of post-cataract endophthalmitis is low, with a range of 0.28 per 1,000 to 2.99 per 1,000. In addition to intraoperative considerations such as poor wound construction, vitreous loss, topical anesthesia, and prolonged surgical time, other risk factors include preoperative factors such as a dis...... hiện toàn bộ
Development of Retinal Amacrine Cells and Their Dendritic StratificationCurrent Ophthalmology Reports - Tập 2 - Trang 100-106 - 2014
Revathi Balasubramanian, Lin Gan
The mammalian retina contains multiple neurons, each of which contributes differentially to visual processing. Of these retinal neurons, amacrine cells have recently come to prime light since they facilitate majority of visual processing that takes place in the retina. Amacrine cells are also the most diverse group of neurons in the retina, classified majorly based on the neurotransmitter type the...... hiện toàn bộ
Refractive IOL Pipeline: Innovations, Predictions, and NeedsCurrent Ophthalmology Reports - Tập 5 - Trang 255-263 - 2017
Gary N. Wörtz, Peyton R. Wörtz
The aim of this paper is to provide an overview of published literature evaluating new refractive intraocular lenses (IOLs). Six categories of refractive IOLs are either currently commercialized in various regions (notably Europe) or under investigation for the treatment of presbyopia. No single category has emerged as a clear market leader, re-emphasizing the need for surgeons to individualize th...... hiện toàn bộ
OCT in the Management of Diabetic Macular EdemaCurrent Ophthalmology Reports - Tập 1 - Trang 128-133 - 2013
Nadia K. Waheed, Jay S. Duker
Diabetic macular edema (DME) is the most common cause of mild-to-moderate visual loss in diabetes. With the introduction of anti-vascular endothelial growth factor therapies in addition to the previously available medical and laser therapies, OCT has become the cornerstone in the diagnosis, monitoring, therapeutic selection, and gauging response to therapy in eyes with DME. A review of the recent ...... hiện toàn bộ