Current Ophthalmology Reports

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Development of Retinal Amacrine Cells and Their Dendritic Stratification
Current Ophthalmology Reports - Tập 2 - Trang 100-106 - 2014
Revathi Balasubramanian, Lin Gan
The mammalian retina contains multiple neurons, each of which contributes differentially to visual processing. Of these retinal neurons, amacrine cells have recently come to prime light since they facilitate majority of visual processing that takes place in the retina. Amacrine cells are also the most diverse group of neurons in the retina, classified majorly based on the neurotransmitter type the...... hiện toàn bộ
Refractive IOL Pipeline: Innovations, Predictions, and Needs
Current Ophthalmology Reports - Tập 5 - Trang 255-263 - 2017
Gary N. Wörtz, Peyton R. Wörtz
The aim of this paper is to provide an overview of published literature evaluating new refractive intraocular lenses (IOLs). Six categories of refractive IOLs are either currently commercialized in various regions (notably Europe) or under investigation for the treatment of presbyopia. No single category has emerged as a clear market leader, re-emphasizing the need for surgeons to individualize th...... hiện toàn bộ
Zika Virus and the Eye: Where Are We Now and Where Are We Heading?
Current Ophthalmology Reports - Tập 5 - Trang 264-269 - 2017
Camila V. Ventura, Raquel Goldhardt, Audina M. Berrocal
New Pharmacological Treatments for Dry Eye Disease
Current Ophthalmology Reports - Tập 1 - Trang 75-79 - 2013
Gary D. Novack
The impact of dry eye disease on patient’s health, visual function and quality of life may be substantial. At present, the only approved pharmacological treatment in the U.S. or Canada is Restasis® (cyclosporine ophthalmic emulsion). In Japan, three products are approved: Hyalein® (hyaluronic acid), Diquas® (diquafasol), and Mucosta® (rebamapide). No pharmacological treatment is currently approved...... hiện toàn bộ
Immunosuppressive Therapy for High-Risk Corneal Transplant
Current Ophthalmology Reports - Tập 10 - Trang 114-129 - 2022
Asma M. Azam, Cameron B. Reinisch, Edward J. Holland, Albert Y. Cheung
This review summarizes the efficacy, clinical utility, and adverse event profile of available immunosuppression agents used for high-risk keratoplasties. New studies are emphasized. Recent studies have highlighted the use of different immunosuppressive agents in the setting of high-risk keratoplasty as well as supporting studies (e.g., immune privilege, panel reactive antibody, HLA matching, graft...... hiện toàn bộ
Extracellular Vesicles: Biomarkers, Therapeutics, and Vehicles in the Visual System
Current Ophthalmology Reports - Tập 5 - Trang 276-282 - 2017
Yolandi van der Merwe, Michael B. Steketee
We discuss recent advances in extracellular vesicle (EV) technology as biomarkers, therapeutics, and drug delivery vehicles in the visual system with an emphasis on the retina. Retinal cell-type specific EVs can be detected in the blood and in the aqueous humor and EV miRNA cargoes can be used diagnostically to predict retinal disease progression. Studies have now shown EVs can deliver bioactive m...... hiện toàn bộ
Swept Source Optical Coherence Tomography: a Review
Current Ophthalmology Reports - Tập 6 - Trang 7-16 - 2018
A. Yasin Alibhai, Chris Or, Andre J. Witkin
In this review, we shall attempt to explain the physics behind swept source-optical coherence tomography (SS-OCT), the advantages and disadvantages of SS-OCT when compared with spectral domain-optical coherence tomography (SD-OCT), and the current clinical applications of SS-OCT. SS-OCT offers improvements in visualizing the vitreous, retina, choroid, and sclera. The increased scan speeds, decreas...... hiện toàn bộ
Cytomegalovirus Keratouveitis: Charted and Uncharted Territory
Current Ophthalmology Reports - Tập 6 - Trang 98-104 - 2018
Ashlin Joye, John Gonzales
This report provides an overview of the current understanding of cytomegalovirus (CMV) keratouveitis: pathophysiology, clinical features, management, and gaps in knowledge. The wide availability of polymerase chain reaction (PCR) testing of ocular fluid has demonstrated that CMV is an important cause of keratouveitis. PCR has more recently been used to offer a microbiologic indicator (viral load),...... hiện toàn bộ
Intense Pulse Light Therapy for Meibomian Gland Dysfunction
Current Ophthalmology Reports - Tập 10 - Trang 138-152 - 2022
Jeremy J. Kudrna, Clever Nguyen, Gargi K. Vora
This article reviews the history, indications, therapeutic safety/efficacy, and suspected mechanisms of action of intense pulse light therapy (IPL) in treating meibomian gland dysfunction (MGD) and related conditions. IPL has been used by dermatologists since the 1980s. Today, through reduction of meibum viscosity, photocoagulation, photobiomodulation, photorejuvenation, and antimicrobial effects,...... hiện toàn bộ
Pediatric Ocular Trauma: an Update
Current Ophthalmology Reports - Tập 5 - Trang 107-113 - 2017
Kyle E. Miller
This article will review the recent literature and discuss the unique aspects to the presentation, evaluation, and treatment of pediatric ocular trauma. Ocular trauma occurs disproportionately in the pediatric population with injury rates and mechanisms similar throughout the world with only minor variation. Trauma in the pediatric population has the potential to cause devastating vision loss. Mos...... hiện toàn bộ
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