Current Oncology Reports

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Risk assessment models to estimate cancer probabilities
Current Oncology Reports - Tập 9 - Trang 503-508 - 2008
Constance M. Johnson, Derek Smolenski
Cancer risk has become a significant research topic due to an increase in statistical risk models built to predict cancer incidence or mortality. Over the past 3 years, 15 models on the development of different types of cancer, including breast, colorectal, prostate, gastric, lung, ovarian, pancreatic, testicular, and skin, have been published. Risk assessment models are dynamic; they need to be u...... hiện toàn bộ
Antagonists of the Mu-Opioid Receptor in the Cancer Patient: Fact or Fiction?
Current Oncology Reports - Tập 24 - Trang 1337-1349 - 2022
Amparo Belltall, Guido Mazzinari, Oscar Diaz-Cambronero, Pilar Eroles, María Pilar Argente Navarro
Antagonists of mu-opioid receptor role in cancer progression remains to be elucidated. The objective of this review was to summarize the available evidence on antagonists of mu-opioid receptor effect on tumor progression and prognosis in different types of cancers and an evaluation of the available findings on their mechanism of action. We have found studies related to methylnaltrexone (MNTX) and ...... hiện toàn bộ
Chimeric Antigen Receptor–Engineered T Cell Therapy in Lymphoma
Current Oncology Reports - Tập 21 - Trang 1-7 - 2019
Paolo Strati, Sattva S. Neelapu
Chimeric antigen receptor (CAR) T cells are a form of adoptive therapy employing autologous T cells engineered with an artificial receptor, able to recognize tumor antigens through an HLA-independent mechanism. We will review data on safety and efficacy outcomes with CAR T cell therapy in lymphomas. Multicenter trials evaluating three CAR T cell products targeting CD19 have shown that they are hig...... hiện toàn bộ
Androgen Deprivation Therapy and Cognitive Function in Prostate Cancer
Current Oncology Reports - Tập 22 - Trang 1-10 - 2020
Jonathan Kluger, Alicia Roy, Herta H. Chao
Androgen deprivation therapy (ADT) is widely used in prostate cancer. Interest in assessing how ADT impacts cognition is growing. Studies in animals and humans suggest that androgens may affect cognitive function. However, extant studies utilizing common neurocognitive tests have not consistently demonstrated ADT-induced cognitive impairment. Retrospective analyses investigating the association be...... hiện toàn bộ
Hodgkin’s disease: Prognostic factors and short-course regimens
Current Oncology Reports - Tập 2 Số 2 - Trang 163-171 - 2000
Nancy L. Bartlett, Sophia M. Arackal
Gene expression profiling of primary breast cancer
Current Oncology Reports - Tập 7 - Trang 38-44 - 2005
Roman Rouzier, Peter Wagner, Paolo Morandi, Lajos Pusztai
Gene expression profiling is a method to measure the expression of a large number of genes in tissue specimens simultaneously. This analytical technique is actively explored as an emerging diagnostic tool for breast cancer. An important assumption behind this research is that the constellation of multiple genes will be more predictive of clinical outcome than any single gene alone. Gene expression...... hiện toàn bộ
Systemic Treatment for Brain Metastasis and Leptomeningeal Disease in Breast Cancer Patients
Current Oncology Reports - - 2023
Sushant Puri, Amina Chaudhry, Asnakech Bayable, Ashwin Ganesh, Ahmad Daher, Vijayakrishna K. Gadi, Stefania Maraka
The evolving management of small renal masses
Current Oncology Reports - Tập 11 - Trang 211-217 - 2009
Stephen A. Boorjian, Robert G. Uzzo
The incidence of small renal masses (SRMs) continues to rise, largely because of the widespread use of cross-sectional imaging for abdominal symptomatology. Clinical management must balance the risk of disease progression from renal cell carcinoma in these tumors against the potential morbidity of treatment, particularly in elderly patients or those with multiple comorbidities. Moreover, a signifi...... hiện toàn bộ
First-Line Therapy for Nodal T-cell Non-Hodgkin Lymphomas: an Unmet Need in Hematology
Current Oncology Reports - - 2023
Vibor Milunović, Inga Mandac Smoljanović, Martina Bogeljić Patekar, Viktor Zatezalo, Marin Kursar, Delfa Radić-Krišto, Slobodanka Ostojić Kolonić, Slavko Gašparov
Monitoring of acute myeloid leukemia by flow cytometry
Current Oncology Reports - Tập 5 - Trang 405-412 - 2003
Wolfgang Kern, Susanne Schnittger
Monitoring of minimal residual disease (MRD) becomes increasingly important in the risk-adapted management of patients with acute myeloid leukemia (AML). In selected patients with AML, multiparameter flow cytometry has shown accuracy and sensitivity in the quantification of MRD levels with independent prognostic impact. The applicability of this approach is superior to that of other methods such a...... hiện toàn bộ
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