Current Oncology Reports
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BCR/ABL-Positive Chronic Myeloid Leukemia in Children: Current Treatment Approach
Current Oncology Reports - - 2024
Cardiovascular Toxicity of Novel HER2-Targeted Therapies in the Treatment of Breast Cancer
Current Oncology Reports - - 2021
Determining Adequate Margins in Head and Neck Cancers: Practice and Continued Challenges
Current Oncology Reports - Tập 18 - Trang 1-7 - 2016
Margin assessment remains a critical component of oncologic care for head and neck cancer patients. As an integrated team, both surgeons and pathologists work together to assess margins in these complex patients. Differences in method of margin sampling can impact obtainable information and effect outcomes. Additionally, what distance is an “adequate or clear” margin for patient care continues to ...... hiện toàn bộ
Progress in Gynecologic Cancers with Antibody Drug Conjugates
Current Oncology Reports - Tập 23 - Trang 1-11 - 2021
This article provides a comprehensive review of antibody-drug conjugates (ADCs) under investigation in gynecologic cancers. The structure and function of ADCs are reviewed with a focus on clinical benefit as well as toxicity profiles. Several ADCs with various target antigens have been investigated in ovarian, cervical, and endometrial cancer. ADCs have consistently demonstrated favorable safety/t...... hiện toàn bộ
Opportunities and Challenges for a Histology-Agnostic Utilization of Trastuzumab Deruxtecan
Current Oncology Reports - - 2023
This review delves into the prospects and challenges offered by a potential pan-histological utilization of trastuzumab deruxtecan (T-DXd) in patients with advanced solid tumors. The HER2-targeted antibody-drug conjugate (ADC) T-DXd has shown broad activity across cancer types, with current indications for patients with biomarker-selected breast, gastric, and non-small-cell lung cancer and relevan...... hiện toàn bộ
Rethinking Clinical Response and Outcome Assessment in a Biologic Age
Current Oncology Reports - Tập 17 - Trang 1-8 - 2015
Standardized response criteria for lymphoma are critical for the evaluation of new therapies. Widely adopted recommendations, most recently the Lugano classification, have been developed primarily for assessment of conventional chemotherapeutic regimens. More recently, several classes of drugs, including immunomodulatory agents, B cell receptor pathway targeting kinases, and checkpoint (PD-1, PDL-...... hiện toàn bộ
Adjuvant chemotherapy for primary breast cancer
Current Oncology Reports - Tập 7 Số 1 - Trang 18-22 - 2005
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