Current Neurology and Neuroscience Reports
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Novel Therapies for Glioblastoma
Current Neurology and Neuroscience Reports - Tập 20 - Trang 1-12 - 2020
Glioblastoma (GBM) is the most common malignant primary brain tumor, and the available treatment options are limited. This article reviews the recent preclinical and clinical investigations that seek to expand the repertoire of effective medical and radiotherapy options for GBM. Recent phase III trials evaluating checkpoint inhibition did not result in significant survival benefit. Select vaccine ...... hiện toàn bộ
Current concepts and controversy in chronic inflammatory demyelinating polyneuropathy
Current Neurology and Neuroscience Reports - Tập 3 Số 1 - Trang 57-63 - 2003
Chronic inflammatory demyelinating polyneuropathy (CIDP) is an acquired, immune-mediated demyelinating neuropathy. It is the most common treatable acquired polyneuropathy and represents a significant number of initially undiagnosed neuropathy patients. This article reviews the common clinical, laboratory, and electrodiagnostic features of CIDP. In addition, current areas of uncertainty are discuss...... hiện toàn bộ
An Update on the Neurologic Applications of Botulinum Toxins
Current Neurology and Neuroscience Reports - Tập 10 - Trang 338-344 - 2010
Initially used to treat strabismus in the 1970s, botulinum toxin now has more than a hundred possible medical applications. Its utility in neurologic conditions has largely involved treating movement disorders (particularly dystonia and conditions with muscle hyperactivity), although practically any hyperkinetic movement disorder may be relieved by botulinum toxin, including hemifacial spasm, trem...... hiện toàn bộ
Computed Tomography Imaging Predictors of Intracerebral Hemorrhage Expansion
Current Neurology and Neuroscience Reports - Tập 21 - Trang 1-8 - 2021
Hematoma expansion (HE) is strongly associated with poor clinical outcome and is a compelling target for improving outcome after intracerebral hemorrhage (ICH). Non-contrast computed tomography (NCCT) is widely used in clinical practice due to its faster acquisition at the presence of acute stroke. Recently, imaging markers on NCCT are increasingly used for predicting HE. We comprehensively review...... hiện toàn bộ
Advances in meningioma therapy
Current Neurology and Neuroscience Reports - Tập 9 - Trang 231-240 - 2009
Meningiomas are the most common primary brain tumors in adults. Most of them are benign (World Health Organization [WHO] grade I), slow-growing lesions, but some are classified as atypical (WHO grade II) or malignant (WHO grade III). Surgical resection is curative when complete removal of a benign meningioma is possible. Incompletely resected tumors and high-grade lesions are frequently treated wi...... hiện toàn bộ
Understanding and Promoting Resiliency in Patients with Chronic Headache
Current Neurology and Neuroscience Reports - Tập 16 - Trang 1-7 - 2015
Even among patients with the same type and severity of headache, there is considerable variability in functional outcomes. Some individuals are resilient, able to thrive despite pain, whereas others find that pain is an overwhelming burden that comes to define their lives. A substantial body of evidence suggests that patients’ cognitive, emotional, and behavioral coping responses to their pain pla...... hiện toàn bộ
The use of monotherapy in patients with epilepsy: An appraisal of the new antiepileptic drugs
Current Neurology and Neuroscience Reports - Tập 5 - Trang 322-328 - 2005
The use of antiepileptic drugs (AEDs) in monotherapy is always preferred to a polytherapy regimen because monotherapy facilitates drug compliance, is associated with a lower risk of toxicity, and is less costly. In addition, the yield of polytherapy to render a patient seizure-free when monotherapy regimens did not is relatively low. The available data derived from randomized controlled trials sug...... hiện toàn bộ
Antiplatelet aggregating versus anticoagulant agents in preventing early recurrent stroke among patients with atrial fibrillation
Current Neurology and Neuroscience Reports - Tập 1 - Trang 11-12 - 2001
Thrombolysis beyond 4.5 h in Acute Ischemic Stroke
Current Neurology and Neuroscience Reports - Tập 20 Số 8 - 2020
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