Kleine-Levin Syndrome

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Kleine-Levin syndrome: functional imaging correlates of hypersomnia and behavioral symptoms. Neurology. 2012;79:1927–9. Hong SB, Joo EY, Tae WS, Lee J, Han SJ, Lee HW. Episodic diencephalic hypoperfusion in Kleine-Levin syndrome. Sleep. 2006;29:1091–3. Kas A, Lavault S, Habert MO, Arnulf I. Feeling unreal: a functional imaging study in patients with Kleine-Levin syndrome. Brain. 2014;137:2077–87. Functional imaging analysis of a large group of patients both during episodes and between episodes. Provides neuroanatomical correlates for common symptoms. Landtblom AM, Dige N, Schwerdt K, Säfström P, Granérus G. A case of Kleine-Levin syndrome examined with SPECT and neuropsychological testing. Acta Neurol Scand. 2002;105:318–21. Landtblom AM, Dige N, Schwerdt K, Säfström P, Granérus G. Short-term memory dysfunction in Kleine-Levin syndrome. Acta Neurol Scand. 2003;108:363–7. Engström M, Vigren P, Karlsson T, Landtblom A-M. Working memory in 8 Kleine-Levin syndrome patients: an fMRI study. 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A case of late-onset Kleine-Levin syndrome responding to lamotrigine. Sleep Med. 2009;10:394. Ortega-Albás JJ, Díaz JR, López-Bernabé R, Vera JF, Alós M, Serrano AL. Treatment of Kleine-Levin syndrome with sodium oxybate. Sleep Med. 2011;12:730. Kapson B, Nayar S, Spiegel R. Treatment of Kleine-Levin syndrome with acetazolamide. J Clin Sleep Med. 2014;10:1153–4. Oliveira MM, Conti C, Saconato H, Fernandes do Prado G. Pharmacological treatment for Kleine-Levin syndrome. Cochrane Database Syst Rev. 2009. doi:10.1002/14651858.CD006685.pub2.