Current Hypertension Reports
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Kích hoạt kéo dài phản xạ áp suất: Một phương pháp khả thi cho việc điều trị tăng huyết áp? Dịch bởi AI
Current Hypertension Reports - Tập 7 - Trang 193-198 - 2005
Ở hầu hết bệnh nhân bị tăng huyết áp, áp lực động mạch vẫn ở mức cao hơn mục tiêu kiểm soát, ngay cả đối với những người đang sử dụng nhiều loại thuốc hạ huyết áp. Trong bài báo này, chúng tôi xem xét lịch sử và tình trạng hiện tại của một phương pháp không dùng thuốc để điều trị tăng huyết áp - kích hoạt điện kéo dài nhánh tiếp nhận của phản xạ áp suất cảnh. Các nghiên cứu gần đây trên chó bình á......
#tăng huyết áp #phương pháp không dùng thuốc #phản xạ áp suất #kích hoạt điện #nghiên cứu lâm sàng
Dual Endothelin Antagonism with Aprocitentan as a Novel Therapeutic Approach for Resistant Hypertension
Current Hypertension Reports - Tập 25 - Trang 343-352 - 2023
Resistant hypertension (RH) defined as uncontrolled blood pressure despite the use of a combination of a renin-angiotensin system blocker, a calcium channel blocker, and a diuretic at maximally tolerated doses is associated with a substantially increased risk of cardiovascular and renal events. Despite targeting relevant pathophysiological pathways contributing to elevated blood pressure, approxim......
Antihypertensive drugs and cognitive function
Current Hypertension Reports - Tập 4 - Trang 211-215 - 2002
The increase in life expectancy is associated with a sharp rise in cognitive disorders, particularly after the age of 80 years. The identification and management of risk factors for these invalidating and distressing conditions must be considered a priority. Hypertension has been shown to carry an increased risk not only for cerebrovascular morbidity and mortality, but also for cognitive impairmen......
Evolution of diagnostic criteria for primary aldosteronism: Why is it more common in "drug-resistant" hypertension today?
Current Hypertension Reports - Tập 6 - Trang 485-492 - 2004
The recent "epidemic" of primary aldosteronism reported in the literature is most likely related to the widespread acceptance that with easy access to accurate measurements of renin and aldosterone, it is no longer necessary to wait until hypokalemia has become profound before embarking on diagnostic testing to attempt to ferret out this most common cause of "essential" hypertension. This is espec......
Cardiovascular Hypertensive Emergencies
Current Hypertension Reports - Tập 17 - Trang 1-6 - 2015
Inevitably, a small proportion of patients with systematic hypertension will develop hypertensive crisis at some point. Hypertensive crises can be divided into hypertensive emergency or hypertensive urgency according to the presence or lack of acute target organ damage. In this review, we discuss cardiovascular hypertensive emergencies, including acute coronary syndrome, aortic dissection, congest......
Ambulatory blood pressure and cardiovascular risk in chronic kidney disease
Current Hypertension Reports - Tập 10 Số 2 - Trang 119-126 - 2008
Diagnosis of hypertension is critically dependent on accurate blood pressure (BP) measurement, especially in patients with chronic kidney disease (CKD), in whom early antihypertensive treatment is imperative to prevent cardiovascular events. Ambulatory BP monitoring (ABPM) has successfully identified hypertensive patients at increased risk, but its role in management of CKD patients is not well de......
Angiotensin-converting enzyme 2: Possible role in hypertension and kidney disease
Current Hypertension Reports - Tập 10 - Trang 70-77 - 2008
The discovery of angiotensin-converting enzyme (ACE) 2 adds a new level of complexity to the understanding of the renin-angiotensin system. The high catalytic efficiency of ACE2 for the generation of angiotensin (ANG)-1-7 from ANG II suggests an important role of ACE2 in preventing ANG II accumulation, while at the same time enhancing ANG-1-7 formation. ACE and ACE2 may have counterbalancing funct......
Genetic Testing for Pheochromocytoma
Current Hypertension Reports - Tập 12 - Trang 456-464 - 2010
Pheochromocytomas (PHEOs) and paragangliomas (PGLs) are rare, catecholamine-producing tumors that are usually sporadic. However, about 30% of these tumors have been identified as being of inherited origin. To date, nine genes have been confirmed as participating in PHEO or PGL tumorigenesis. Germline mutations were found in 100% of syndromic cases and in about 90% of patients with positive familia......
Arterial stiffness and wave reflection in hypertension: Pathophysiologic and therapeutic implications
Current Hypertension Reports - Tập 6 - Trang 436-441 - 2004
Numerous studies performed in the past decade have shown that increased pulse pressure, an indicator of arterial stiffening, is associated with adverse clinical outcomes. Research is now focused on better defining the anatomic and physiologic determinants of increased pulse pressure. Early work considered aortic stiffening to be a passive, irreversible consequence of aging that was accelerated by ......
Role of angiotensin III in hypertension
Current Hypertension Reports - Tập 7 Số 2 - Trang 128-134 - 2005
The hyperactivity of the brain renin-angiotensin system (RAS) has been implicated in the development and maintenance of hypertension in several types of experimental and genetic hypertension animal models. Among the main bioactive peptides of the brain RAS, angiotensin (Ang) II and Ang III display the same affinity for type 1 and type 2 Ang II receptors. Both peptides, injected intracerebroventric......
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