Current Controlled Trials in Cardiovascular Medicine

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Tamoxifen is not associated with increased CV event rate
Current Controlled Trials in Cardiovascular Medicine - Tập 2 - Trang 1-3 - 2001
Joanna Lyford
Long-term vitamin E supplementation fails to reduce lipid peroxidation in people at cardiovascular risk: analysis of underlying factors
Current Controlled Trials in Cardiovascular Medicine - Tập 3 Số 1 - 2002
Chiara Chiabrando, Fausto Avanzini, Claudia Rivalta, F. Colombo, Roberto Fanelli, Gaetana Palumbo, Maria Carla Roncaglioni
Combining short stent implantation and drug-eluting stenting for routine use yields a low restenosis rate
Current Controlled Trials in Cardiovascular Medicine - Tập 6 - Trang 1-6 - 2005
Ulrich Dietz, Cheryl Dauer, Heinz Lambertz
Stent length serves as a predictor of restenosis in use of bare metal stents (BMS). This has been demonstrated in a feasibility study that used a single short BMS implant (<9 mm) in a high proportion of lesions; the study observed a low rate of restenosis. We performed a pilot prospective study to investigate in a series of consecutive patients the immediate and long-term effects of implantation o...... hiện toàn bộ
The current status of primary prevention in coronary heart disease
Current Controlled Trials in Cardiovascular Medicine - Tập 2 - Trang 1-14 - 2001
Cornel Pater
During the second part of the twentieth century, research advances caused a substantial decline in the rate of coronary heart disease. The decline lasted from the mid-1960s until the early 1990s and occurred primarily in Western countries. However, an unfavourable trend in coronary heart disease related mortality has gradually developed during the 1990s, with cardiovascular diseases anticipated to...... hiện toàn bộ
A Review of the Adverse Effects of Peripheral Alpha-1 Antagonists in Hypertension Therapy
Current Controlled Trials in Cardiovascular Medicine - Tập 3 - Trang 1-7 - 2002
Chris L Bryson, Bruce M Psaty
Doxazosin and its role as an antihypertensive agent have come under recent scrutiny as a result of the early termination of that treatment arm in ALLHAT. It is unclear why the cardiovascular (CV) event rate in this randomized, controlled trial (RCT), especially heart failure, is higher in those treated with a doxazosin-based regimen than with a chlorthalidone based-regimen. There has been little w...... hiện toàn bộ
Diabetes and insulin use on AMI survival - is enough being done?
Current Controlled Trials in Cardiovascular Medicine - Tập 2 - Trang 1-3 - 2001
Joanna Lyford
Debate: "How low should LDL cholesterol be lowered for optimum prevention of vascular disease?" Viewpoint: "Below 100 mg/dl"
Current Controlled Trials in Cardiovascular Medicine - Tập 2 - Trang 1-4 - 2001
W Virgil Brown
Arteriosclerotic vascular disease manifests as heart disease, stroke, aortic aneurysms, and peripheral vascular disease, and is a growing problem world-wide. The preventive efforts made so far have demonstrated that lowering LDL-C is one action that individuals and populations can do with significant success in delaying the onset of clinical events. Epidemiological studies and small clinical trial...... hiện toàn bộ
Risk of intraparenchymal stroke increased by low saturated fat intake in women
Current Controlled Trials in Cardiovascular Medicine - Tập 2 - Trang 1-3 - 2001
Joanna Lyford
Compliance of a cobalt chromium coronary stent alloy – the COVIS trial
Current Controlled Trials in Cardiovascular Medicine - Tập 6 - Trang 1-4 - 2005
Jens Hagemeister, Frank M Baer, Robert HG Schwinger, Hans W Höpp
Cobalt chromium coronary stents are increasingly being used in percutaneous coronary interventions. There are, however, no reliable data about the characteristics of unfolding and visibility of this stent alloy in vivo. The aim of this study is to compare cobalt chromium coronary stents with conventional stainless steel stents using intracoronary ultrasound. Twenty de novo native coronary stenoses...... hiện toàn bộ
Fundamental deficiencies in the megatrial methodology
Current Controlled Trials in Cardiovascular Medicine - Tập 2 - Trang 1-6 - 2001
Bruce G Charlton
The fundamental methodological deficiency of megatrials is deliberate reduction of experimental control in order to maximize recruitment and compliance of subjects. Hence, typical megatrials recruit pathologically and prognostically heterogeneous subjects, and protocols typically fail to exclude significant confounders. Therefore, most megatrials do not test a scientific hypothesis, nor are they i...... hiện toàn bộ
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