Combining short stent implantation and drug-eluting stenting for routine use yields a low restenosis rateCurrent Controlled Trials in Cardiovascular Medicine - Tập 6 - Trang 1-6 - 2005
Ulrich Dietz, Cheryl Dauer, Heinz Lambertz
Stent length serves as a predictor of restenosis in use of bare metal stents (BMS). This has been demonstrated in a feasibility study that used a single short BMS implant (<9 mm) in a high proportion of lesions; the study observed a low rate of restenosis. We performed a pilot prospective study to investigate in a series of consecutive patients the immediate and long-term effects of implantation o...... hiện toàn bộ
A Review of the Adverse Effects of Peripheral Alpha-1 Antagonists in Hypertension TherapyCurrent Controlled Trials in Cardiovascular Medicine - Tập 3 - Trang 1-7 - 2002
Chris L Bryson, Bruce M Psaty
Doxazosin and its role as an antihypertensive agent have come under recent scrutiny as a result of the early termination of that treatment arm in ALLHAT. It is unclear why the cardiovascular (CV) event rate in this randomized, controlled trial (RCT), especially heart failure, is higher in those treated with a doxazosin-based regimen than with a chlorthalidone based-regimen. There has been little w...... hiện toàn bộ
Compliance of a cobalt chromium coronary stent alloy – the COVIS trialCurrent Controlled Trials in Cardiovascular Medicine - Tập 6 - Trang 1-4 - 2005
Jens Hagemeister, Frank M Baer, Robert HG Schwinger, Hans W Höpp
Cobalt chromium coronary stents are increasingly being used in percutaneous coronary interventions. There are, however, no reliable data about the characteristics of unfolding and visibility of this stent alloy in vivo. The aim of this study is to compare cobalt chromium coronary stents with conventional stainless steel stents using intracoronary ultrasound. Twenty de novo native coronary stenoses...... hiện toàn bộ
The Blood Pressure "Uncertainty Range" – a pragmatic approach to overcome current diagnostic uncertainties (II)Current Controlled Trials in Cardiovascular Medicine - - 2005
Cornel Pater
Abstract
A tremendous amount of scientific evidence regarding the physiology and physiopathology of high blood pressure combined with a sophisticated therapeutic arsenal is at the disposal of the medical community to counteract the overall public health burden of hypertension. Ample evidence has also been gathered from a multitude of large-scale randomize...... hiện toàn bộ
Carotid intimal-media thickness as a surrogate for cardiovascular disease events in trials of HMG-CoA reductase inhibitorsCurrent Controlled Trials in Cardiovascular Medicine - Tập 6 - Trang 1-6 - 2005
Mark A Espeland, Daniel H O'Leary, James G Terry, Timothy Morgan, Greg Evans, Harald Mudra
Surrogate measures for cardiovascular disease events have the potential to increase greatly the efficiency of clinical trials. A leading candidate for such a surrogate is the progression of intima-media thickness (IMT) of the carotid artery; much experience has been gained with this endpoint in trials of HMG-CoA reductase inhibitors (statins). We examine two separate systems of criteria that have ...... hiện toàn bộ