Computational Intelligence and Neuroscience

This paper describes FieldTrip, an open source software package that we developed for the analysis of MEG, EEG, and other electrophysiological data. The software is implemented as a MATLAB toolbox and includes a complete set of consistent and user-friendly high-level functions that allow experimental neuroscientists to analyze experimental data. It includes algorithms for simple and advanced analysis, such as time-frequency analysis using multitapers, source reconstruction using dipoles, distributed sources and beamformers, connectivity analysis, and nonparametric statistical permutation tests at the channel and source level. The implementation as toolbox allows the user to perform elaborate and structured analyses of large data sets using the MATLAB command line and batch scripting. Furthermore, users and developers can easily extend the functionality and implement new algorithms. The modular design facilitates the reuse in other software packages.

Over the last years deep learning methods have been shown to outperform previous state-of-the-art machine learning techniques in several fields, with computer vision being one of the most prominent cases. This review paper provides a brief overview of some of the most significant deep learning schemes used in computer vision problems, that is, Convolutional Neural Networks, Deep Boltzmann Machines and Deep Belief Networks, and Stacked Denoising Autoencoders. A brief account of their history, structure, advantages, and limitations is given, followed by a description of their applications in various computer vision tasks, such as object detection, face recognition, action and activity recognition, and human pose estimation. Finally, a brief overview is given of future directions in designing deep learning schemes for computer vision problems and the challenges involved therein.

This paper describes methods to analyze the brain's electric fields recorded with multichannel Electroencephalogram (EEG) and demonstrates their implementation in the software CARTOOL. It focuses on the analysis of the spatial properties of these fields and on quantitative assessment of changes of field topographies across time, experimental conditions, or populations. Topographic analyses are advantageous because they are reference independents and thus render statistically unambiguous results. Neurophysiologically, differences in topography directly indicate changes in the configuration of the active neuronal sources in the brain. We describe global measures of field strength and field similarities, temporal segmentation based on topographic variations, topographic analysis in the frequency domain, topographic statistical analysis, and source imaging based on distributed inverse solutions. All analysis methods are implemented in a freely available academic software package called CARTOOL. Besides providing these analysis tools, CARTOOL is particularly designed to visualize the data and the analysis results using 3-dimensional display routines that allow rapid manipulation and animation of 3D images. CARTOOL therefore is a helpful tool for researchers as well as for clinicians to interpret multichannel EEG and evoked potentials in a global, comprehensive, and unambiguous way.

Brain-computer interface (BCI) systems based on the steady-state visual evoked potential (SSVEP) provide higher information throughput and require shorter training than BCI systems using other brain signals. To elicit an SSVEP, a repetitive visual stimulus (RVS) has to be presented to the user. The RVS can be rendered on a computer screen by alternating graphical patterns, or with external light sources able to emit modulated light. The properties of an RVS (e.g., frequency, color) depend on the rendering device and influence the SSVEP characteristics. This affects the BCI information throughput and the levels of user safety and comfort. Literature on SSVEP-based BCIs does not generally provide reasons for the selection of the used rendering devices or RVS properties. In this paper, we review the literature on SSVEP-based BCIs and comprehensively report on the different RVS choices in terms of rendering devices, properties, and their potential influence on BCI performance, user safety and comfort.

We present a program (Ragu; Randomization Graphical User interface) for statistical analyses of multichannel event-related EEG and MEG experiments. Based on measures of scalp field differences including all sensors, and using powerful, assumption-free randomization statistics, the program yields robust, physiologically meaningful conclusions based on the entire, untransformed, and unbiased set of measurements. Ragu accommodates up to two within-subject factors and one between-subject factor with multiple levels each. Significance is computed as function of time and can be controlled for type II errors with overall analyses. Results are displayed in an intuitive visual interface that allows further exploration of the findings. A sample analysis of an ERP experiment illustrates the different possibilities offered by Ragu. The aim of Ragu is to maximize statistical power while minimizing the need for a-priori choices of models and parameters (like inverse models or sensors of interest) that interact with and bias statistics.

This short survey the reviews recent literature on brain connectivity studies. It encompasses all forms of static and dynamic connectivity whether anatomical, functional, or effective. The last decade has seen an ever increasing number of studies devoted to deduce functional or effective connectivity, mostly from functional neuroimaging experiments. Resting state conditions have become a dominant experimental paradigm, and a number of resting state networks, among them the prominent default mode network, have been identified. Graphical models represent a convenient vehicle to formalize experimental findings and to closely and quantitatively characterize the various networks identified. Underlying these abstract concepts are anatomical networks, the so-called connectome, which can be investigated by functional imaging techniques as well. Future studies have to bridge the gap between anatomical neuronal connections and related functional or effective connectivities.

This paper presents a patient-specific epileptic seizure predication method relying on the common spatial pattern- (CSP-) based feature extraction of scalp electroencephalogram (sEEG) signals. Multichannel EEG signals are traced and segmented into overlapping segments for both preictal and interictal intervals. The features extracted using CSP are used for training a linear discriminant analysis classifier, which is then employed in the testing phase. A leave-one-out cross-validation strategy is adopted in the experiments. The experimental results for seizure prediction obtained from the records of 24 patients from the CHB-MIT database reveal that the proposed predictor can achieve an average sensitivity of 0.89, an average false prediction rate of 0.39, and an average prediction time of 68.71 minutes using a 120-minute prediction horizon.

The Harmony Search (HS) method is an emerging metaheuristic optimization algorithm, which has been employed to cope with numerous challenging tasks during the past decade. In this paper, the essential theory and applications of the HS algorithm are first described and reviewed. Several typical variants of the original HS are next briefly explained. As an example of case study, a modified HS method inspired by the idea of Pareto-dominance-based ranking is also presented. It is further applied to handle a practical wind generator optimal design problem.

In recent years, financial market dynamics forecasting has been a focus of economic research. To predict the price indices of stock markets, we developed an architecture which combined Elman recurrent neural networks with stochastic time effective function. By analyzing the proposed model with the linear regression, complexity invariant distance (CID), and multiscale CID (MCID) analysis methods and taking the model compared with different models such as the backpropagation neural network (BPNN), the stochastic time effective neural network (STNN), and the Elman recurrent neural network (ERNN), the empirical results show that the proposed neural network displays the best performance among these neural networks in financial time series forecasting. Further, the empirical research is performed in testing the predictive effects of SSE, TWSE, KOSPI, and Nikkei225 with the established model, and the corresponding statistical comparisons of the above market indices are also exhibited. The experimental results show that this approach gives good performance in predicting the values from the stock market indices.

Emerging technologies such as digital twins, blockchain, Internet of Things (IoT), and Artificial Intelligence (AI) play a vital role in driving the industrial revolution in all domains, including the healthcare sector. As a result of COVID-19 pandemic outbreak, there is a significant need for medical cyber-physical systems to adopt these emerging technologies to combat COVID-19 paramedic crisis. Also, acquiring secure real-time data exchange and analysis across multiple participants is essential to support the efforts against COVID-19. Therefore, we have introduced a blockchain-based collaborative digital twins framework for decentralized epidemic alerting to combat COVID-19 and any future pandemics. The framework has been proposed to bring together the existing advanced technologies (i.e., blockchain, digital twins, and AI) and then provide a solution to decentralize epidemic alerting to combat COVID-19 outbreaks. Also, we have described how the conceptual framework can be applied in the decentralized COVID-19 pandemic alerting use case.