Clinical and Molecular Allergy

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Management of the patient with allergic and immunological disorders in the pandemic COVID-19 era
Clinical and Molecular Allergy - Tập 18 - Trang 1-7 - 2020
Vincenzo Patella, Gabriele Delfino, Giovanni Florio, Giuseppe Spadaro, Fulvia Chieco Bianchi, Gianerico Senna, Mario Di Gioacchino
The pandemic COVID-19 abruptly exploded, taking most health professionals around the world unprepared. Italy, the first European country to be hit violently, was forced to activate the lockdown in mid-February 2020. At the time of the spread, a high number of victims were quickly registered, especially in the regions of Northern Italy which have a high rate of highly-polluting production activitie... hiện toàn bộ
Chitinase 3-like-1 is produced by human Th17 cells and correlates with the level of inflammation in juvenile idiopathic arthritis patients
Clinical and Molecular Allergy - Tập 14 - Trang 1-9 - 2016
Manuela Capone, Laura Maggi, Veronica Santarlasci, Maria Caterina Rossi, Alessio Mazzoni, Gianni Montaini, Rolando Cimaz, Matteo Ramazzotti, Marie Pierre Piccinni, Giusi Barra, Raffaele De Palma, Francesco Liotta, Enrico Maggi, Sergio Romagnani, Francesco Annunziato, Lorenzo Cosmi
CHI3L1 is a chitinase-like protein without enzymatic activity, produced by activated macrophages, chondrocytes, neutrophils. Recent studies on arthritis, asthma, and inflammatory bowel diseases suggest that chitinases are important in inflammatory processes and tissue remodeling, but their production by human T cells, has never been reported. A microarray analysis of gene expression profile was pe... hiện toàn bộ
Rituximab in refractory sarcoidosis: a single centre experience
Clinical and Molecular Allergy - Tập 13 - Trang 1-5 - 2015
Francesco Cinetto, Nicolò Compagno, Riccardo Scarpa, Giacomo Malipiero, Carlo Agostini
Sarcoidosis is a granulomatous disease whose outcome varies from spontaneous remission to chronic refractory disease. Provided that steroids represent the gold standard as a first line treatment, many immune suppressants drugs are currently used in the disease management. However, refractory disease is still a great challenge. Rituximab is an anti-CD20 chimeric monoclonal antibody, currently used ... hiện toàn bộ
The silent sinus syndrome: protean manifestations of a rare upper respiratory disorder revisited
Clinical and Molecular Allergy - - 2013
Denisse E Guillen, Paulette Pinargote, Juan Guarderas
Abstract Silent Sinus Syndrome (SSS) is known to be a rare clinical condition, characterized by spontaneous and progressive enophthalmos and hypoglobus associated with atelectasis of the maxillary sinus and alteration of the orbital floor. Most of the patients with this syndrome present with ophthalmological complaints without any nasal sinus symptoms, and it typically has a painless course and sl... hiện toàn bộ
Sensitization profile in patients with respiratory allergic diseases: differences between conventional and molecular diagnosis (a cross-sectional study)
Clinical and Molecular Allergy - Tập 17 - Trang 1-9 - 2019
Guillermo Til-Pérez, Claudio Carnevale, Pedro Luis Sarría-Echegaray, Diego Arancibia-Tagle, Sendy Chugo-Gordillo, Manuel David Tomás-Barberán
Component-resolved diagnosis (CRD) allows to identify single molecular allergen components, and constitutes a routine practice in many allergy units. However, skin prick test (SPT) remains the technique of choice in many otorhinolaryngology departments, thus increasing the risk of using inadequate immunotherapies in patients with respiratory allergies. This study aimed to compare sensitization pro... hiện toàn bộ
Skin microbiota of first cousins affected by psoriasis and atopic dermatitis
Clinical and Molecular Allergy - Tập 14 - Trang 1-11 - 2016
Lorenzo Drago, Roberta De Grandi, Gianfranco Altomare, Paolo Pigatto, Oliviero Rossi, Marco Toscano
Psoriasis and atopic dermatitis (AD) are chronic inflammatory skin diseases, which negatively influence the quality of life. In the last years, several evidences highlighted the pivotal role of skin bacteria in worsening the symptomatology of AD and psoriasis. In the present study we evaluated the skin microbiota composition in accurately selected subjects affected by (AD) and psoriasis. Three fir... hiện toàn bộ
PPI adverse drugs reactions: a retrospective study
Clinical and Molecular Allergy - Tập 17 Số 1 - 2019
Marco Casciaro, Michele Navarra, Giuseppina Inferrera, Marta Liotta, Sebastiano Gangemi, Paola Lucia Minciullo
Association between HMGB1 and asthma: a literature review
Clinical and Molecular Allergy - Tập 15 - Trang 1-9 - 2017
Egidio Imbalzano, Sebastiano Quartuccio, Eleonora Di Salvo, Teresa Crea, Marco Casciaro, Sebastiano Gangemi
Recently, some studies demonstrated that HMGB1, as proinflammatory mediator belonging to the alarmin family, has a key role in different acute and chronic immune disorders. Asthma is a complex disease characterised by recurrent and reversible airflow obstruction associated to airway hyper-responsiveness and airway inflammation. This literature review aims to analyse advances on HMGB1 role, employm... hiện toàn bộ
Rapid clinical improvement of atopic dermatitis in an Omalizumab treated patient
Clinical and Molecular Allergy - Tập 17 - Trang 1-3 - 2019
Susanna Bormioli, Andrea Matucci, Laura Dies, Francesca Nencini, Francesca Grosso, Enrico Maggi, Alessandra Vultaggio
Atopic dermatitis is a chronic inflammatory skin disorder, whose symptoms and severity grossly depend on individual trigger factors. The majority of patients are satisfactorily treated with emollients together with topical and systemic therapies. However, treatment failure or long-term side effects with conventional treatment options can be a significant clinical problem. Recently, novel therapeut... hiện toàn bộ
The effect of vitamin D, magnesium and zinc supplements on interferon signaling pathways and their relationship to control SARS-CoV-2 infection
Clinical and Molecular Allergy - Tập 19 - Trang 1-10 - 2021
Mohsen Nabi-Afjadi, Hadis Karami, Kaveh Goudarzi, Iraj Alipourfard, Elham Bahreini
The concern of today's communities is to find a way to prevent or treat COVID-19 and reduce its symptoms in the patients. However, the genetic mutations and more resistant strains of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerge; the designed vaccines and adjuvant therapies would potentially control the symptoms and severity of COVID-19. The most important complication of thi... hiện toàn bộ
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