Clinical and Molecular Allergy
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Chitinase 3-like-1 is produced by human Th17 cells and correlates with the level of inflammation in juvenile idiopathic arthritis patients
Clinical and Molecular Allergy - Tập 14 - Trang 1-9 - 2016
CHI3L1 is a chitinase-like protein without enzymatic activity, produced by activated macrophages, chondrocytes, neutrophils. Recent studies on arthritis, asthma, and inflammatory bowel diseases suggest that chitinases are important in inflammatory processes and tissue remodeling, but their production by human T cells, has never been reported. A microarray analysis of gene expression profile was pe......
Skin microbiota of first cousins affected by psoriasis and atopic dermatitis
Clinical and Molecular Allergy - Tập 14 - Trang 1-11 - 2016
Psoriasis and atopic dermatitis (AD) are chronic inflammatory skin diseases, which negatively influence the quality of life. In the last years, several evidences highlighted the pivotal role of skin bacteria in worsening the symptomatology of AD and psoriasis. In the present study we evaluated the skin microbiota composition in accurately selected subjects affected by (AD) and psoriasis.
Three f......
PPI adverse drugs reactions: a retrospective study
Clinical and Molecular Allergy - Tập 17 Số 1 - 2019
Rapid clinical improvement of atopic dermatitis in an Omalizumab treated patient
Clinical and Molecular Allergy - Tập 17 - Trang 1-3 - 2019
Atopic dermatitis is a chronic inflammatory skin disorder, whose symptoms and severity grossly depend on individual trigger factors. The majority of patients are satisfactorily treated with emollients together with topical and systemic therapies. However, treatment failure or long-term side effects with conventional treatment options can be a significant clinical problem. Recently, novel therapeut......
The effect of vitamin D, magnesium and zinc supplements on interferon signaling pathways and their relationship to control SARS-CoV-2 infection
Clinical and Molecular Allergy - Tập 19 - Trang 1-10 - 2021
The concern of today's communities is to find a way to prevent or treat COVID-19 and reduce its symptoms in the patients. However, the genetic mutations and more resistant strains of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerge; the designed vaccines and adjuvant therapies would potentially control the symptoms and severity of COVID-19. The most important complication of thi......
Cutaneous reaction to ifosfamide plus mesna treated with desensitization challenge: a case report
Clinical and Molecular Allergy - Tập 20 - Trang 1-4 - 2022
Ifosfamide is an alkylating agent used in the treatment of a wide range of tumours. Because of known side effects it is usually administered in combination with mesna, a thiol agent with uroprotective activity, to reduce them and increase the therapeutic dose. The most frequently administered regimens for ifosfamide are fractionated doses for 3 to 5 days, high-dose intravenous bolus, and continuou......
Early gene expression changes with rush immunotherapy
Clinical and Molecular Allergy - Tập 9 - Trang 1-10 - 2011
To examine whether whole genome expression profiling could reveal changes in mRNA expression of peripheral blood mononuclear cells (PBMC) from allergic patients undergoing rush immunotherapy (RIT) that might be manifest within the first few months of treatment. For this study, PBMC from three allergic patients undergoing RIT were assessed at four timepoints: prior to RIT, at 1 week and 7 week post......
Tropomyosin in mugwort cross-reacts to house dust mite, eliciting non-Th2 response in allergic rhinitis patients sensitized to house dust mite
Clinical and Molecular Allergy - Tập 19 - Trang 1-9 - 2021
Mugwort and house dust mite (HDM) are two of the most common inhalant allergens in Asia, however, whether mugwort affects polysensitized HDM+ allergic rhinitis (AR) patients has not been elucidated. Overall, 15,884 AR outpatients were assessed for clinical status. Amino acid sequences of mugwort were determined by mass spectrometry. Afterward, cross-reactivity between mugwort tropomyosin and Derma......
Exhaled nitric oxide and urinary EPX levels in infants: a pilot study
Clinical and Molecular Allergy - Tập 9 - Trang 1-8 - 2011
Objective markers of early airway inflammation in infants are not established but are of great interest in a scientific setting. Exhaled nitric oxide (FeNO) and urinary eosinophilic protein X (uEPX) are a two such interesting markers. To investigate the feasibility of measuring FeNO and uEPX in infants and their mothers and to determine if any relations between these two variables and environmenta......
Allergy to lingonberry: A case report
Clinical and Molecular Allergy - Tập 2 - Trang 1-3 - 2004
Past few years cranberry/lingonberry products have been incorporated as healthy products to the US and European market as prophylaxis of recurrent urinary tract infections in young women as well as in chronic infections in elderly which because of there are many biological activities attributed to the that fruit is a very popular additive to the new diets. To the best of our knowledge, this is the......
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