Clinical and Molecular Allergy
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Severe asthma and the omalizumab option
Clinical and Molecular Allergy - Tập 6 - Trang 1-13 - 2008
Atopic diseases and asthma are increasing at a remarkable rate on a global scale. It is now well recognized that asthma is a chronic inflammatory disease of the airways. The inflammatory process in many patients is driven by an immunoglobulin E (IgE)-dependent process. Mast cell activation and release of mediators, in response to allergen and IgE, results in a cascade response, culminating in B ly...... hiện toàn bộ
Prevalence of positive atopy patch test in an unselected pediatric population
Clinical and Molecular Allergy - - 2015
In the latest decades, epidemiological studies on allergic disorders in children, including atopic dermatitis, rhinitis and asthma, demonstrated a continuous increase in prevalence. However, such studies are usually performed by questionnaires and, sometimes, by skin prick test or in vitro IgE tests, while the portion of allergy sustained by the cell-mediated mechanism is neglected, because the es...... hiện toàn bộ
The risk of anaphylaxis behind authorized COVID-19 vaccines: a meta-analysis
Clinical and Molecular Allergy - Tập 20 - Trang 1-9 - 2022
A serious allergic reaction that may occur in response to medical products is anaphylaxis, which potentially can lead to anaphylactic shock. In the light of recent COVID-19 pandemic, much public attention had been paid to the severe allergic reactions occurring after COVID-19 vaccination. Therefore, in our study we would like to investigate the risk of authorized COVID-19 vaccines to induce anaphy...... hiện toàn bộ
T helper cell mediated-tolerance towards fetal allograft in successful pregnancy
Clinical and Molecular Allergy - Tập 13 - Trang 1-5 - 2015
Trophoblast HLA-C antigens from paternal origins, which liken the trophoblast to a semiallograft, could be presented by the maternal APCs to the specific maternal CD4+ T helper cells, which could release various cytokines in response to these alloantigens. On the basis of the cytokines produced, these cells can be classified in Th1, Th2 and Th17 cells. Th1 and Th17 cells, known to be responsible f...... hiện toàn bộ
The effect of vitamin D, magnesium and zinc supplements on interferon signaling pathways and their relationship to control SARS-CoV-2 infection
Clinical and Molecular Allergy - Tập 19 - Trang 1-10 - 2021
The concern of today's communities is to find a way to prevent or treat COVID-19 and reduce its symptoms in the patients. However, the genetic mutations and more resistant strains of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerge; the designed vaccines and adjuvant therapies would potentially control the symptoms and severity of COVID-19. The most important complication of thi...... hiện toàn bộ
Association between a low IgE response to Phl p 5 and absence of asthma in patients with grass pollen allergy
Clinical and Molecular Allergy - Tập 11 - Trang 1-4 - 2013
The introduction of component-resolved diagnosis was a great advance in diagnosis of allergy. In particular, molecular allergy techniques allowed investigation of the association between given molecular profiles and clinical expression of allergy. We evaluated the possible correlation between the level of specific IgE (sIgE) to single components of Phleum pratense and clinical issues such as the s...... hiện toàn bộ
Does improvement management of atopic dermatitis influence the appearance of respiratory allergic diseases? A follow-up study
Clinical and Molecular Allergy - Tập 8 - Trang 1-12 - 2010
Atopic dermatitis (AD) is often the prelude to allergic diseases. The aim of this study was 1) to evaluate if an integrated management regime could bring about a change in the evolution of the disease in comparison to the results of a previous study; 2) to determine whether the refinement of allergic investigations allowed to identify more promptly the risk factors of evolution into respiratory al...... hiện toàn bộ
Molecular and immunological characterization of allergens from the entomopathogenic fungus Beauveria bassianaAbstract Background Entomopathogenic fungi such asBeauveria bassiana are considered promising biological control agents for a variety of arthropod pests.Beauveria species, however, have the potential to elicit allergenic reactions in humans, although no specific allergens have been...
Clinical and Molecular Allergy - - 2006
The clinical implications of adult-onset henoch-schonelin purpura
Clinical and Molecular Allergy - Tập 9 - Trang 1-7 - 2011
Henoch-Schonlein Purpura (HSP) is a small vessel vasculitis mediated by IgA-immune complex deposition. It is characterized by the clinical tetrad of non-thrombocytopenic palpable purpura, abdominal pain, arthritis and renal involvement. Pathologically, it can be considered a form of immune complex-mediated leukocytoclastic vasculitis (LCV) involving the skin and other organs. Though it primarily a...... hiện toàn bộ
Eosinophilia in a patient with cyclical vomiting: a case report
Clinical and Molecular Allergy - Tập 2 - Trang 1-11 - 2004
Eosinophilic gastritis is related to eosinophilic gastroenteritis, varying only in regards to the extent of disease and small bowel involvement. Common symptoms reported are similar to our patient's including: abdominal pain, epigastric pain, anorexia, bloating, weight loss, diarrhea, ankle edema, dysphagia, melaena and postprandial nausea and vomiting. Microscopic features of eosinophilic infiltr...... hiện toàn bộ
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