Clinical and Experimental Allergy

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Effects of celecoxib on major prostaglandins in asthma
Clinical and Experimental Allergy - Tập 41 Số 1 - Trang 36-45 - 2011
Kameran Daham, Wen‐Liang Song, John Lawson, Maciej Kupczyk, A Gülich, Sven‐Erik Dahlén, Garret A. FitzGerald, Barbro Dahlén
Cyclooxygenase 2: its regulation, role and impact in airway inflammation
Clinical and Experimental Allergy - Tập 46 Số 3 - Trang 397-410 - 2016
Nowshin N. Rumzhum, Alaina J. Ammit
SummaryCyclooxygenase 2 (COX‐2: official gene symbol – PTGS2) has long been regarded as playing a pivotal role in the pathogenesis of airway inflammation in respiratory diseases including asthma. COX‐2 can be rapidly and robustly expressed in response to a diverse range of pro‐inflammatory cytokines and mediators. Thus, increased levels of COX‐2 protein and prostan...... hiện toàn bộ
Relevance of Ara h1, Ara h2 and Ara h3 in peanut‐allergic patients, as determined by immunoglobulin E Western blotting, basophil–histamine release and intracutaneous testing: Ara h2 is the most important peanut allergen
Clinical and Experimental Allergy - Tập 34 Số 4 - Trang 583-590 - 2004
Stef J. Koppelman, Michel Wensing, M. Ertmann, André C. Knulst, Edward F. Knol
SummaryBackground A number of allergenic proteins in peanut has been described and the relative importance of these allergens is yet to be determined.Objectives We have investigated the relevance of previously identified peanut allergens in well‐characterized peanut‐allergic patients by ... hiện toàn bộ
Immunoglobulin G4: an odd antibody
Clinical and Experimental Allergy - Tập 39 Số 4 - Trang 469-477 - 2009
Rob C. Aalberse, Steven O. Stapel, Janine Schuurman, Theo Rispens
SummaryDespite its well‐known association with IgE‐mediated allergy, IgG4 antibodies still have several poorly understood characteristics. IgG4 is a very dynamic antibody: the antibody is involved in a continuous process of half‐molecules (i.e. a heavy and attached light‐chain) exchange. This process, also referred to as ‘Fab‐arm exchange’, results usually in asymm...... hiện toàn bộ
Comparison of four allergen‐sampling methods in conventional and allergy prevention classrooms
Clinical and Experimental Allergy - Tập 32 Số 12 - Trang 1776-1781 - 2002
Anne-Sophie Karlsson, Anne Renström, Marie Hedrén, Kristin Larsson
SummaryBackground Several allergen‐sampling methods are used to assess level of personal or indirect exposure to cat in homes, schools and other public buildings and working environments.Objective To compare four different allergen‐sampling methods (dust collectors, Petri dishes, person‐carried pumps an...... hiện toàn bộ
Personal exposure to allergenic pollen and mould spores in inland New South Wales, Australia
Clinical and Experimental Allergy - Tập 30 Số 12 - Trang 1733-1739 - 2000
T. Z. Mitakakis, Euan R. Tovey, Wei Xuan, Guy B. Marks
BackgroundIn inland NSW, Australia, allergic sensitization to the fungi Alternaria and Cladosporium and to pollen is common and an important risk factor for asthma.ObjectiveWe report the results of a series of experiments designed to assess...... hiện toàn bộ
Increased chitinase expression and fungal‐specific antibodies in the bronchoalveolar lavage fluid of asthmatic children
Clinical and Experimental Allergy - Tập 42 Số 4 - Trang 523-530 - 2012
David L. Goldman, X. Li, Kalliope Tsirilakis, Cristiane Conte Paim de Andrade, Arturo Casadevall, Alfin G. Vicencio
SummaryBackgroundIncreasing evidence highlights the contribution of chitinases and fungal infection to the development of asthma.ObjectiveThe purpose of this study was to characterize chitinase expression and serological markers of fungal infection in children with sev...... hiện toàn bộ
A standardized densitometric immunoblotting analysis of Candida albicans protein allergens
Clinical and Experimental Allergy - Tập 25 Số 4 - Trang 357-363 - 1995
Johannes Savolainen
SummarySera from 196 patients with a strong skin reactivity to Candida albicans and a history of atopic disease were used for C. albicans IgE‐immunoblotting. The IgE‐immunoblots were analysed by densitometry and integration of the densitogram peaks. A standardized reference disc system allowed parallel analysis ...... hiện toàn bộ
Predominance of the major allergen (Alt a I) in Alternaria sensitized patients
Clinical and Experimental Allergy - Tập 23 Số 3 - Trang 211-218 - 1993
Jörg Kleine‐Tebbe, Margitta Worm, S. Jeep, Finn Matthiesen, Henning Løwenstein, G. KUNKEL
SummaryThirty‐nine patients sensitized to Alternaria were evaluated using titrated skin‐prick test (SPT), histamine release studies (HR), inhibition of RAST and immunoblotting studies. To determine the relevance of the major allergen, Alt a I, specific rabbit antibodies against Alt a I...... hiện toàn bộ
Influence of viral infection on the development of nasal hypersensitivity
Clinical and Experimental Allergy - Tập 35 Số 5 - Trang 679-684 - 2005
Yoshitaka Okamoto, Zensei Matsuzaki, T Matsuoka, S. Endo, Hideki Yamamoto, Hideaki Chazono, S. Horiguchi, Toyoyuki Hanazawa
SummaryBackground The underlying relationship between viral infections and allergic diseases of the upper respiratory tract has not been well clarified.Methods In order to clarify the relationship between viral infection and nasal hypersensitivity, mice were sensitized with ovalbumin (OVA) a...... hiện toàn bộ
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