Cyclooxygenase 2: its regulation, role and impact in airway inflammationClinical and Experimental Allergy - Tập 46 Số 3 - Trang 397-410 - 2016
Nowshin N. Rumzhum, Alaina J. Ammit
SummaryCyclooxygenase 2 (COX‐2: official gene symbol – PTGS2) has long been regarded as playing a pivotal role in the pathogenesis of airway inflammation in respiratory diseases including asthma. COX‐2 can be rapidly and robustly expressed in response to a diverse range of pro‐inflammatory cytokines and mediators. Thus, increased levels of COX‐2 protein and prostan...... hiện toàn bộ
Immunoglobulin G4: an odd antibodyClinical and Experimental Allergy - Tập 39 Số 4 - Trang 469-477 - 2009
Rob C. Aalberse, Steven O. Stapel, Janine Schuurman, Theo Rispens
SummaryDespite its well‐known association with IgE‐mediated allergy, IgG4 antibodies still have several poorly understood characteristics. IgG4 is a very dynamic antibody: the antibody is involved in a continuous process of half‐molecules (i.e. a heavy and attached light‐chain) exchange. This process, also referred to as ‘Fab‐arm exchange’, results usually in asymm...... hiện toàn bộ
Comparison of four allergen‐sampling methods in conventional and allergy prevention classroomsClinical and Experimental Allergy - Tập 32 Số 12 - Trang 1776-1781 - 2002
Anne-Sophie Karlsson, Anne Renström, Marie Hedrén, Kristin Larsson
SummaryBackground Several allergen‐sampling methods are used to assess level of personal or indirect exposure to cat in homes, schools and other public buildings and working environments.Objective To compare four different allergen‐sampling methods (dust collectors, Petri dishes, person‐carried pumps an...... hiện toàn bộ
Personal exposure to allergenic pollen and mould spores in inland New South Wales, AustraliaClinical and Experimental Allergy - Tập 30 Số 12 - Trang 1733-1739 - 2000
T. Z. Mitakakis, Euan R. Tovey, Wei Xuan, Guy B. Marks
BackgroundIn inland NSW, Australia, allergic sensitization to the fungi Alternaria and Cladosporium and to pollen is common and an important risk factor for asthma.ObjectiveWe report the results of a series of experiments designed to assess...... hiện toàn bộ
A standardized densitometric immunoblotting analysis of Candida albicans protein allergensClinical and Experimental Allergy - Tập 25 Số 4 - Trang 357-363 - 1995
Johannes Savolainen
SummarySera from 196 patients with a strong skin reactivity to Candida albicans and a history of atopic disease were used for C. albicans IgE‐immunoblotting. The IgE‐immunoblots were analysed by densitometry and integration of the densitogram peaks. A standardized reference disc system allowed parallel analysis ...... hiện toàn bộ
Predominance of the major allergen (Alt a I) in Alternaria sensitized patientsClinical and Experimental Allergy - Tập 23 Số 3 - Trang 211-218 - 1993
Jörg Kleine‐Tebbe, Margitta Worm, S. Jeep, Finn Matthiesen, Henning Løwenstein, G. KUNKEL
SummaryThirty‐nine patients sensitized to Alternaria were evaluated using titrated skin‐prick test (SPT), histamine release studies (HR), inhibition of RAST and immunoblotting studies. To determine the relevance of the major allergen, Alt a I, specific rabbit antibodies against Alt a I...... hiện toàn bộ
Influence of viral infection on the development of nasal hypersensitivityClinical and Experimental Allergy - Tập 35 Số 5 - Trang 679-684 - 2005
Yoshitaka Okamoto, Zensei Matsuzaki, T Matsuoka, S. Endo, Hideki Yamamoto, Hideaki Chazono, S. Horiguchi, Toyoyuki Hanazawa
SummaryBackground
The underlying relationship between viral infections and allergic diseases of the upper respiratory tract has not been well clarified.Methods
In order to clarify the relationship between viral infection and nasal hypersensitivity, mice were sensitized with ovalbumin (OVA) a...... hiện toàn bộ