Exercise Hemodynamics Enhance Diagnosis of Early Heart Failure With Preserved Ejection Fraction Tập 3 Số 5 - Trang 588-595 - 2010
Barry A. Borlaug, Rick A. Nishimura, Paul Sorajja, Carolyn S.P. Lam, Margaret M. Redfield
Background— When advanced, heart failure with preserved ejection fraction
(HFpEF) is readily apparent. However, diagnosis of earlier disease may be
challenging because exertional dyspnea is not specific for heart failure, and
biomarkers and hemodynamic indicators of volume overload may be absent at rest.
Methods and Results— Patients with exertional dyspnea and ejection fraction >50%
were referred... hiện toàn bộ
Exercise Training in Patients With Heart Failure and Preserved Ejection Fraction Tập 8 Số 1 - Trang 33-40 - 2015
Ambarish Pandey, Akhil Parashar, Dharam J. Kumbhani, Sunil Agarwal, Jalaj Garg, Dalane W. Kitzman, Benjamin D. Levine, Mark H. Drazner, Jarett D. Berry
Background— Heart failure with preserved ejection fraction (HFPEF) is common and
characterized by exercise intolerance and lack of proven effective therapies.
Exercise training has been shown to be effective in improving cardiorespiratory
fitness (CRF) in patients with systolic heart failure. In this meta-analysis, we
aim to evaluate the effects of exercise training on CRF, quality of life, and
di... hiện toàn bộ
Cardiac Structure and Function in Heart Failure With Preserved Ejection Fraction Tập 7 Số 1 - Trang 104-115 - 2014
Amil M. Shah, Sanjiv J. Shah, Inder S. Anand, Nancy K. Sweitzer, Eileen O’Meara, John F. Heitner, George Sopko, Guichu Li, Susan F. Assmann, Sonja M. McKinlay, Bertram Pitt, Marc A. Pfeffer, Scott D. Solomon
Background— Heart failure with preserved ejection fraction (HFpEF) is associated
with substantial morbidity and mortality. Existing data on cardiac structure and
function in HFpEF suggest significant heterogeneity in this population. Methods
and Results— Echocardiograms were obtained from 935 patients with HFpEF (left
ventricular ejection fraction ≥45%) enrolled in the Treatment of Preserved
Cardi... hiện toàn bộ
Percutaneous Left-Ventricular Support With the Impella-2.5–Assist Device in Acute Cardiogenic Shock Tập 6 Số 1 - Trang 23-30 - 2013
Alexander Lauten, Annemarie E. Engström, Christian Jung, Klaus Empen, Paul Erné, Stéphane Cook, Stephan Windecker, Martin Bergmann, Roland Klingenberg, Thomas F. Lüscher, Michael Haude, Dierk Rulands, Christian Butter, Bengt Ullman, Laila Hellgren, Maria Grazia Modena, Giovanni Pedrazzini, José P.S. Henriques, Hans R. Figulla, Markus Ferrari
Background— Acute cardiogenic shock after myocardial infarction is associated
with high in-hospital mortality attributable to persisting low-cardiac output.
The Impella–EUROSHOCK-registry evaluates the safety and efficacy of the
Impella-2.5–percutaneous left-ventricular assist device in patients with
cardiogenic shock after acute myocardial infarction. Methods and Results— This
multicenter registr... hiện toàn bộ
Predictors of New-Onset Heart Failure Tập 6 Số 2 - Trang 279-286 - 2013
Jennifer E. Ho, Asya Lyass, Douglas S. Lee, Ramachandran S. Vasan, William B. Kannel, Martin G. Larson, Daniel Levy
Background— About one half of patients with heart failure (HF) have preserved
ejection fraction (HFPEF) rather than reduced ejection fraction (HFREF). The
differences in risk factors predisposing to the 2 subtypes of HF are poorly
understood. We sought to identify clinical predictors of new-onset HF and to
explore differences in HFPEF versus HFREF. Methods and Results— We studied
new-onset HF case... hiện toàn bộ
Analysis of Metabolic Remodeling in Compensated Left Ventricular Hypertrophy and Heart Failure Tập 3 Số 3 - Trang 420-430 - 2010
Takao Kato, Shinichiro Niizuma, Yasutaka Inuzuka, Tsuneaki Kawashima, Jun Okuda, Yodo Tamaki, Yoshitaka Iwanaga, Michiko Narazaki, Tetsuya Matsuda, Tomoyoshi Soga, Toru Kita, Takeshi Kimura
Background— Congestive heart failure (CHF) is associated with a change in
cardiac energy metabolism. However, the mechanism by which this change is
induced and causes the progression of CHF is unclear. Methods and Results— We
analyzed the cardiac energy metabolism of Dahl salt-sensitive rats fed a
high-salt diet, which showed a distinct transition from compensated left
ventricular hypertrophy to C... hiện toàn bộ
Diagnosis, Treatment, and Outcome of Giant-Cell Myocarditis in the Era of Combined Immunosuppression Tập 6 Số 1 - Trang 15-22 - 2013
Riina Kandolin, Jukka Lehtonen, Kaisa Salmenkivi, Anne Räisänen‐Sokolowski, Jyri Lommi, Markku Kupari
Background— Giant-cell myocarditis often escapes diagnosis until autopsy or
transplantation and has defied proper treatment trials for its rarity and deadly
behavior. Current therapy rests on multiple-drug immunosuppression but its
prognostic influence remains poorly known. We set out to analyze (1) our
experience in diagnosing giant-cell myocarditis and (2) the outcome of patients
on combined imm... hiện toàn bộ
Cardiac Structure and Function and Prognosis in Heart Failure With Preserved Ejection Fraction Tập 7 Số 5 - Trang 740-751 - 2014
Amil M. Shah, Brian Claggett, Nancy K. Sweitzer, Sanjiv J. Shah, Inder S. Anand, Eileen O’Meara, Akshay S. Desai, John F. Heitner, Guichu Li, James C. Fang, Jean L. Rouleau, Michael R. Zile, В. А. Марков, V. V. Ryabov, Gilmar Reis, Susan F. Assmann, Sonja M. McKinlay, Bertram Pitt, Marc A. Pfeffer, Scott D. Solomon
Background— Abnormalities in cardiac structure and function in heart failure
with preserved ejection fraction may help identify patients at particularly high
risk for cardiovascular morbidity and mortality. Methods and Results— Cardiac
structure and function were assessed by echocardiography in a blinded core
laboratory at baseline in 935 patients with heart failure with preserved
ejection fractio... hiện toàn bộ
Physical Function, Frailty, Cognition, Depression, and Quality of Life in Hospitalized Adults ≥60 Years With Acute Decompensated Heart Failure With Preserved Versus Reduced Ejection Fraction Tập 11 Số 11 - 2018
Haider J. Warraich, Dalane W. Kitzman, David J. Whellan, Pamela W. Duncan, Robert J. Mentz, Amy M. Pastva, M. Benjamin Nelson, Bharathi Upadhya, Gordon R. Reeves
Background: Older hospitalized acute decompensated heart failure (HF) patients
have persistently poor outcomes and delayed recovery regardless of ejection
fraction (EF). We hypothesized that impairments in physical function, frailty,
cognition, mood, and quality of life (QoL) potentially contributing to poor
clinical outcomes would be similarly severe in acute decompensated HF patients
≥60 years o... hiện toàn bộ