Circulation: Heart Failure

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Cardiac Structure and Function and Prognosis in Heart Failure With Preserved Ejection Fraction
Circulation: Heart Failure - Tập 7 Số 5 - Trang 740-751 - 2014
Amil M. Shah, Brian Claggett, Nancy K. Sweitzer, Sanjiv J. Shah, Inder S. Anand, Eileen O’Meara, Akshay S. Desai, John F. Heitner, Guichu Li, James C. Fang, Jean L. Rouleau, Michael R. Zile, В. А. Марков, V. V. Ryabov, Gilmar Reis, Susan F. Assmann, Sonja M. McKinlay, Bertram Pitt, Marc A. Pfeffer, Scott D. Solomon
Background— Abnormalities in cardiac structure and function in heart failure with preserved ejection fraction may help identify patients at particularly high risk for cardiovascular morbidity and mortality. Methods and Results— ... hiện toàn bộ
Outcomes of Patients With Peripartum Cardiomyopathy Who Received Mechanical Circulatory Support
Circulation: Heart Failure - Tập 7 Số 2 - Trang 300-309 - 2014
Renzo Y. Loyaga‐Rendon, Salpy V. Pamboukian, José Tallaj, Deepak Acharya, Ryan S. Cantor, Randall C. Starling, David C. Naftel, James K. Kirklin
Background— We describe the characteristics and outcomes of peripartum cardiomyopathy (PPCMP) patients who received durable mechanical circulatory support and compared it with other etiologies of advanced heart failure. Methods and Results— ...... hiện toàn bộ
Exercise Training in Patients With Heart Failure and Preserved Ejection Fraction
Circulation: Heart Failure - Tập 8 Số 1 - Trang 33-40 - 2015
Ambarish Pandey, Akhil Parashar, Dharam J. Kumbhani, Sunil Agarwal, Jalaj Garg, Dalane W. Kitzman, Benjamin D. Levine, Mark H. Drazner, Jarett D. Berry
Background— Heart failure with preserved ejection fraction (HFPEF) is common and characterized by exercise intolerance and lack of proven effective therapies. Exercise training has been shown to be effective in improving cardiorespiratory fitness (CRF) in patients with systolic heart failure. In this meta-analysis, we aim to evalu...... hiện toàn bộ
Dose-Dependent Effects of the Myosin Activator Omecamtiv Mecarbil on Cross-Bridge Behavior and Force Generation in Failing Human Myocardium
Circulation: Heart Failure - Tập 10 Số 10 - 2017
Ranganath Mamidi, Jiayang Li, Kenneth S. Gresham, Sujeet Verma, Chang Yoon Doh, Amy Li, Sean Lal, Cristobal G. dos Remedios, Julian E. Stelzer
Background: Omecamtiv mecarbil (OM) enhances systolic function in vivo by directly binding the myosin cross-bridges (XBs) in the sarcomere. However, the mechanistic details governing OM-induced modulation of XB behavior in failing human myocardium are unclear. ... hiện toàn bộ
Cardiac Structure and Function in Heart Failure With Preserved Ejection Fraction
Circulation: Heart Failure - Tập 7 Số 1 - Trang 104-115 - 2014
Amil M. Shah, Sanjiv J. Shah, Inder S. Anand, Nancy K. Sweitzer, Eileen O’Meara, John F. Heitner, George Sopko, Guichu Li, Susan F. Assmann, Sonja M. McKinlay, Bertram Pitt, Marc A. Pfeffer, Scott D. Solomon
Background— Heart failure with preserved ejection fraction (HFpEF) is associated with substantial morbidity and mortality. Existing data on cardiac structure and function in HFpEF suggest significant heterogeneity in this population. Methods and Results—... hiện toàn bộ
Hypochloremia, Diuretic Resistance, and Outcome in Patients With Acute Heart Failure
Circulation: Heart Failure - Tập 9 Số 8 - 2016
Jozine M. ter Maaten, Kevin Damman, Jennifer S. Hanberg, Michael R. Zile, Marco Metra, Christopher M. O’Connor, John R. Teerlink, Piotr Ponikowski, Gad Cotter, Beth A. Davison, John G.F. Cleland, Daniel M. Bloomfield, Hans L. Hillege, Dirk J. van Veldhuisen, Adriaan A. Voors, Jef Van den Eynde
Background— Chloride plays a role in renal salt sensing, neurohormonal activation, and regulation of diuretic targets, and hypochloremia predicts mortality in acute heart failure (AHF). AHF therapies, such as diuretics, alter chloride homeostasis. We studied the association between (changes in) chloride levels and diuretic respons...... hiện toàn bộ
Serum Chloride and Sodium Interplay in Patients With Acute Myocardial Infarction and Heart Failure With Reduced Ejection Fraction
Circulation: Heart Failure - Tập 10 Số 2 - 2017
João Pedro Ferreira, Nicolas Girerd, Kévin Duarte, Stefano Coiro, John J.V. McMurray, Henry J. Dargie, Bertram Pitt, Kenneth McDonald, Jeffrey M. Testani, Faı̈ez Zannad, Patrick Rossignol
Background— Serum chloride levels were recently found to be independently associated with mortality in heart failure (HF). Methods and Results— We investigated the relationship between serum chloride and clin...... hiện toàn bộ
Importance of Abnormal Chloride Homeostasis in Stable Chronic Heart Failure
Circulation: Heart Failure - Tập 9 Số 1 - 2016
Justin L. Grodin, Frederik H. Verbrugge, Stephen G. Ellis, Wilfried Mullens, Jeffrey M. Testani, W.H. Wilson Tang
Background— The aim of this analysis was to determine the long-term prognostic value of lower serum chloride in patients with stable chronic heart failure. Electrolyte abnormalities are prevalent in patients with chronic heart failure. Little is known regarding the prognostic implications of lower serum chloride. ...... hiện toàn bộ
Determining the Preferred Percent-Predicted Equation for Peak Oxygen Consumption in Patients With Heart Failure
Circulation: Heart Failure - Tập 2 Số 2 - Trang 113-120 - 2009
Ross Arena, Jonathan Myers, Joshua Abella, Sherry Pinkstaff, Peter H. Brubaker, Brian Moore, Dalane W. Kitzman, Mary Ann Peberdy, Daniel Bensimhon, Paul Chase, Daniel E. Forman, Erin West, Marco Guazzi
Background— Peak oxygen consumption (V o 2 ) is routinely assessed in patients with heart failure undergoing cardiopulmonary exercise testing. The purpose of the present investigation was to determine the prognost...... hiện toàn bộ
The Natural History of Preclinical Diastolic Dysfunction
Circulation: Heart Failure - Tập 5 Số 2 - Trang 144-151 - 2012
Mark W. Vogel, Joshua P. Slusser, David O. Hodge, Horng H. Chen
Background— Preclinical diastolic dysfunction (PDD) has been broadly defined as subjects with left ventricular diastolic dysfunction, without the diagnosis of congestive heart failure (HF) and with normal systolic function. Our objective was to determine the risk factors associated with the progression from PDD (stage B) HF to sym...... hiện toàn bộ
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